Ulcero-osteolytic lesions in a woman with type 2 diabetes and carpal tunnel syndrome: A case report and literature review

2016 ◽  
Vol 113 ◽  
pp. 204-207 ◽  
Author(s):  
Elisabetta L. Romeo ◽  
Marcello Previti ◽  
Annalisa Giandalia ◽  
Giuseppina T. Russo ◽  
Domenico Cucinotta
Keyword(s):  
Type 2 Diabetes ◽  
Case Report ◽  
Carpal Tunnel Syndrome ◽  
Literature Review ◽  
Carpal Tunnel ◽  
Osteolytic Lesions ◽  
Tunnel Syndrome

Ultrasound-guided insulin injection for carpal tunnel syndrome in type 2 diabetes mellitus patients

2019 ◽  
Vol 38 (10) ◽  
pp. 2933-2940
Author(s):  
Shereen Refaat Kamel ◽  
Hanaa A. Sadek ◽  
Ahmed Hamed ◽  
Omima A. Sayed ◽  
Mona H. Mahmud ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Insulin Injection ◽  
Ultrasound Guided ◽  
Tunnel Syndrome

scholarly journals Case Report: Presentation of an unusual cause of carpal tunnel syndrome with accompanying literature review

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 319
Author(s):  
Paul Patiniott ◽  
Matheesha Herath ◽  
Peter Riddell
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Carpal Tunnel Syndrome ◽  
Literature Review ◽  
Carpal Tunnel ◽  
Arteriovenous Malformations ◽  
High Flow ◽  
Complex Issue ◽  
Tunnel Syndrome ◽  
Report Presentation

Background: Carpal tunnel syndrome (CTS) is a condition seen commonly in clinical practice; high-flow arteriovenous malformations (AVM) can be a rare but important cause. Case Report: We discuss a case of a patient who had developed left CTS in the fifth decade of life as the result of a progressively enlarging congenital peripheral AVM affecting his left upper limb. This case illustrates the clinical challenges encountered in the surgical and interventional management of this complex issue. Discussion:High-flow AVMs affecting the extremities may be comprised of a convoluted network of vessels in high-flow, low-resistance systems that often recur despite intervention. Conclusion: Peripheral AVM affecting the hand can be a rare and therapeutically challenging cause of carpal tunnel syndrome that warrants multidisciplinary team discussion.

scholarly journals Atypical Carpal Tunnel Syndrome in a Holt Oram Patient: A Case Report and Literature Review

2014 ◽  
Vol 8 (1) ◽  
pp. 462-465
Author(s):  
James Mace ◽  
Srikanth Reddy ◽  
Randeep Mohil
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Magnetic Resonance ◽  
Carpal Tunnel Syndrome ◽  
Literature Review ◽  
Median Nerve ◽  
Carpal Tunnel ◽  
Clinical Effect ◽  
Resonance Imaging ◽  
Tunnel Syndrome

We present a case report of a patient diagnosed with Holt-Oram syndrome (HOS) presenting with clinical and electrophysiologically confirmed carpal tunnel syndrome. Pre-operative Magnetic resonance imaging revealed an abnormal course of the median nerve; as such an atypical incision and approach were carried out to decompress the nerve to excellent post operative clinical effect. To our knowledge this is the first description of abnormal nervous course in a patient with HOS leading to peripheral entrapment. A literature surrounding the important aspects of HOS to the orthopaedic surgeon is presented concomitantly.

scholarly journals Estimating the causal effect of adiposity on carpal tunnel syndrome: a Mendelian randomization study

2019 ◽  
Author(s):  
Iyas Daghlas ◽  
Nathan Varady
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Mendelian Randomization ◽  
Causal Effect ◽  
Sensitivity Analyses ◽  
Abdominal Adiposity ◽  
Tunnel Syndrome

AbstractBackgroundWe aimed to examine evidence for a causal effect of overall and abdominal adiposity on carpal tunnel syndrome (CTS) using two-sample Mendelian randomization (MR).MethodsThe exposure included genetic instruments comprising independent variants associated with body mass index (BMI) (n=322,154), a proxy for overall adiposity, and waist-hip ratio adjusted for BMI (WHRadjBMI) (n=210,082), a proxy for abdominal adiposity. Associations of these variants with CTS were obtained from a genome-wide association study (GWAS) conducted in UK Biobank (12,312 CTS cases / 389,344 controls). Causal effects were estimated using inverse-variance weighted regression and conventional MR sensitivity analyses were conducted to assess for horizontal pleiotropy. In follow-up analyses we determined whether type 2 diabetes (T2D) or hyperlipidemia mediated the observed effects.ResultsA 1-standard deviation (SD, ∼4.7kg/m2) increase in genetically instrumented BMI increased the risk of CTS (OR 1.73, 95% CI 1.48-2.02, p=2.68e-12), with consistent effects across sensitivity analyses. This effect translates to an absolute increase of 17 CTS cases per 1000 person years amongst US working populations [95% CI 11.0-23.5]. Univariable MR was consistent with a causal effect of T2D (OR 1.08, 95% CI 1.03-1.11, p=5.20e-05), and the effect of BMI was partially attenuated (OR 1.53, 95% CI 1.38-1.68, p=2.85e-08) when controlling for T2D liability in multivariable MR. In contrast, no effect was observed of WHRadjBMI on CTS (OR 1.03, 95% CI 0.74-1.33, p=0.83).ConclusionThese data support a causal effect of overall adiposity on susceptibility to CTS that is only partially mediated through T2D, suggesting that efforts to reduce obesity may mitigate the population burden of CTS.Key messages- A one-standard deviation increase in body mass index, a proxy for overall adiposity, increased risk of carpal tunnel by 73%. In contrast, no effect of waist-to-hip ratio adjusted for BMI, a proxy for abdominal adiposity, was observed on risk of carpal tunnel syndrome.- The effects of BMI on carpal tunnel syndrome risk were partially attenuated when accounting for mediation through type 2 diabetes, suggesting that the majority of the causal effect operates independently of diabetes risk.- These data suggest that efforts to reduce rates of obesity could reduce the incidence of carpal tunnel syndrome.

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