Memantine transport by a proton-coupled organic cation antiporter in hCMEC/D3 cells, an in vitro human blood-brain barrier model

2015 ◽  
Vol 30 (2) ◽  
pp. 182-187 ◽  
Author(s):  
Kei Higuchi ◽  
Atsushi Kitamura ◽  
Takashi Okura ◽  
Yoshiharu Deguchi
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Organic Cation ◽  
Brain Barrier ◽  
Blood Brain ◽  
Blood Brain Barrier Model ◽  
Barrier Model

scholarly journals Zika virus crosses an in vitro human blood brain barrier model

2018 ◽  
Vol 15 (1) ◽  
Author(s):  
Judie B. Alimonti ◽  
Maria Ribecco-Lutkiewicz ◽  
Caroline Sodja ◽  
Anna Jezierski ◽  
Danica B. Stanimirovic ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Zika Virus ◽  
Brain Barrier ◽  
Blood Brain ◽  
Blood Brain Barrier Model ◽  
Barrier Model

scholarly journals Silver nanoparticle-induced expression of proteins related to oxidative stress and neurodegeneration in an in vitro human blood-brain barrier model

2019 ◽  
Vol 13 (2) ◽  
pp. 221-239 ◽  
Author(s):  
Asif Manzoor Khan ◽  
Barbara Korzeniowska ◽  
Vladimir Gorshkov ◽  
Muhammad Tahir ◽  
Henrik Schrøder ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Brain Barrier ◽  
Silver Nanoparticle ◽  
Human Blood ◽  
Brain Barrier ◽  
Induced Expression ◽  
Blood Brain ◽  
Blood Brain Barrier Model ◽  
Barrier Model

scholarly journals Saccharomyces cerevisiae show low levels of traversal across the human blood brain barrier in vitro

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 944 ◽  
Author(s):  
Roberto Pérez-Torrado ◽  
Amparo Querol
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Blood Brain Barrier ◽  
Human Blood ◽  
Brain Barrier ◽  
Blood Brain ◽  
Blood Brain Barrier Model ◽  
Low Levels ◽  
Systemic Infections ◽  
Barrier Model

Background: Saccharomyces cerevisiaeis generally considered safe, and is involved in the production of many types of foods and dietary supplements. However, some isolates, which are genetically related to strains used in brewing and baking, have shown virulent traits, being able to produce infections in humans, mainly in immunodeficient patients. This can lead to systemic infections in humans.Methods: In this work, we studiedS. cerevisiaeisolates in anin vitrohuman blood brain barrier model, comparing their behaviour with that of several strains of the related pathogensCandida glabrataandCandida albicans.Results: The results showed that this food related yeast is able to cross the blood brain barrierin vitro.However, in contrast toC. glabrataandC. albicans,S. cerevisiaeshowed very low levels of traversal.Conclusions: We conclude that using anin vitrohuman blood brain barrier model withS. cerevisiaecan be useful to evaluate the safety ofS. cerevisiaestrains isolated from foods.

scholarly journals Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model

2015 ◽  
Vol 6 (11) ◽  
pp. 1849-1859 ◽  
Author(s):  
Hisham Qosa ◽  
Yazan S. Batarseh ◽  
Mohamed M. Mohyeldin ◽  
Khalid A. El Sayed ◽  
Jeffrey N. Keller ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Amyloid Β ◽  
Brain Barrier ◽  
Blood Brain ◽  
Blood Brain Barrier Model ◽  
Barrier Model
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