scholarly journals Association between fluoride exposure and kidney function in adults: A cross-sectional study based on endemic fluorosis area in China

2021 ◽  
Vol 225 ◽  
pp. 112735
Author(s):  
Liaowei Wu ◽  
Chenlu Fan ◽  
Zaihong Zhang ◽  
Xin Zhang ◽  
Qun Lou ◽  
...  
Keyword(s):  
Kidney Function ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Endemic Fluorosis ◽  
Cross Sectional ◽  
Fluoride Exposure

scholarly journals Haematological profile of chronic kidney disease in a mixed-ancestry South African population: a cross-sectional study

BMJ Open ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. e025694 ◽  
Author(s):  
Cindy George ◽  
Tandi E Matsha ◽  
Rajiv T Erasmus ◽  
Andre P Kengne
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Blood Cell ◽  
Kidney Function ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mixed Ancestry ◽  
Cross Sectional ◽  
Haematological Profile ◽  
Rbc Indices

ObjectivesThe objectives were to characterise the haematological profile of screen-detected chronic kidney disease (CKD) participants and to correlate the complete blood count measures with the commonly advocated kidney function estimators.MethodsThe current cross-sectional study used data, collected between February 2015 and November 2016, of 1564 adults of mixed-ancestry, who participated in the Cape Town Vascular and Metabolic Health study. Kidney function was estimated using the Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations. CKD was defined as estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2, and anaemia as haemoglobin level <13.5 g/dL (men) and <12 g/dL (women).ResultsBased on the MDRD and CKD-EPI equations, the crude prevalence of CKD was 6% and 3%. Irrespective of the equation used, median red blood cell (RBC) indices were consistently lower in those with CKD compared with those without CKD (all p<0.0001). Despite not showing any significant difference in total white blood cell (WBC) count between the two groups, the number of lymphocytes were lower (p=0.0001 and p<0.0001 for MDRD and CKD-EPI, respectively) and neutrophil count (both p<0.0297) and the ratio of lymphocytes to neutrophil (both p<0.0001) higher in the CKD group compared with those without CKD; with the remaining WBC indices similar in the two groups. The platelet count was similar in both groups. Of the screen-detected CKD participants, 45.5% (MDRD) and 57.8% (CKD-EPI) were anaemic, with the prevalence increasing with increasing severity of CKD, from 37.2% (stage 3) to 82.4% (stages 4–5). Furthermore, CKD-EPI-estimated kidney function, but not MDRD, was positively associated with RBC indices.ConclusionThough it remains unclear whether common kidney function estimators provide accurate estimates of CKD in Africans, the correlation of their estimates with deteriorating RBC profile, suggests that advocated estimators, to some extent approximate kidney function in African populations.

scholarly journals Prevalence of Dental Caries among 13 and 15-Year-Old School Children in an Endemic Fluorosis Area: A Cross-sectional Study

2011 ◽  
Vol 12 (6) ◽  
pp. 447-450 ◽  
Author(s):  
P Sudhakar ◽  
K Amarendher Reddy ◽  
BR Anuradha ◽  
G Sri Laxmi ◽  
VN Malik ◽  
...  
Keyword(s):  
Dental Caries ◽  
School Children ◽  
Andhra Pradesh ◽  
Dental Fluorosis ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Male Students ◽  
Sectional Study ◽  
Endemic Fluorosis ◽  
Cross Sectional

ABSTRACT Aim To assess the prevalence of dental caries and dental fluorosis among 13- to 15-year-old school children in Panyam, Andhra Pradesh, India. Materials and methods The cross-sectional study was conducted among 202 school children and were examined for dental fluorosis and dental caries. Results This study shows that male students have a decrease in DMFT (Decayed, missing, filled, teeth) index and increase in Dean's index when compared with females. Among students with 13 to 15 years of age, 13-year-old student has increase in DMFT score when compared with other age groups and 14-year-old students has increase in Dean's score when compared with other age group students. Conclusion The prevalence of dental caries decreased with the increase of fluorosis among the students examined. Clinical significance Patients with dental fluorosis show a decreased prevalence of dental caries. How to cite this article Anuradha BR, Sri Laxmi G, Sudhakar P, Malik VN, Reddy KA, Reddy SN, Prasanna AL. Prevalence of Dental Caries among 13 and 15-Year-Old School Children in an Endemic Fluorosis Area: A Cross-sectional Study. J Contemp Dent Pract 2011;12(6):447-450.

scholarly journals Evaluating Kidney Function in Elderly Population: A Cross-Sectional Study in Primary Health Care

2017 ◽  
Vol 06 (01) ◽  
Author(s):  
Zoi Tsimtsiou ◽  
Konstantina Karakoula ◽  
Elpida Efthymiadou ◽  
Antonios Asimakopoulos ◽  
Basiliki Fardi ◽  
...  
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Kidney Function ◽  
Elderly Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Primary Health

scholarly journals Fluoride exposure and sleep patterns among older adolescents in the United States: a cross-sectional study of NHANES 2015–2016

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Ashley J. Malin ◽  
Sonali Bose ◽  
Stefanie A. Busgang ◽  
Chris Gennings ◽  
Michael Thorpy ◽  
...  
Keyword(s):  
United States ◽  
Daytime Sleepiness ◽  
The United States ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Sleep Patterns ◽  
Cross Sectional ◽  
Fluoride Exposure ◽  
Older Adolescents ◽  
Water Fluoride

Abstract Background Fluoride from environmental sources accumulates preferentially in the pineal gland which produces melatonin, the hormone that regulates the sleep-wake cycle. However, the effects of fluoride on sleep regulation remain unknown. This population-based study examined whether chronic low-level fluoride exposure is associated with sleep patterns and daytime sleepiness among older adolescents in the United States (US). Method This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2015–2016). We analyzed data from adolescents who had plasma fluoride (n = 473) and water fluoride (n = 419) measures and were not prescribed medication for sleep disorders. Relationships between fluoride exposure and self-reported sleep patterns or daytime sleepiness were examined using survey-weighted linear, binomial logistic or multinomial logistic regression after covariate adjustment. A Holm-Bonferroni correction accounted for multiple comparisons. Results The average age of adolescents was 17 years (range = 16–19). Median (IQR) water and plasma fluoride concentrations were 0.27 (0.52) mg/L and 0.29 (0.19) μmol/L respectively. An IQR increase in water fluoride was associated with 1.97 times higher odds of reporting symptoms suggestive of sleep apnea (95% CI: 1.27, 3.05; p = 0.02), a 24 min later bedtime (B = 0.40, 95% CI: 0.10, 0.70; p = 0.05), a 26 min later morning wake time (B = 0.43, 95% CI: 0.13, 0.73; p = 0.04), and among males, a 38% reduction in the odds of reporting snoring (95% CI: 0.45, 0.87, p = 0.03). Conclusions Fluoride exposure may contribute to changes in sleep cycle regulation and sleep behaviors among older adolescents in the US. Additional prospective studies are warranted to examine the effects of fluoride on sleep patterns and determine critical windows of vulnerability for potential effects.

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