Risk factors associated with adverse drug events among older adults in emergency department

Aims and objectives: To determine the risk factors of blood culture contamination done in ED and those done in the MHDU/MICU among patients admitted with medical illness. Material and Methods: This is a two months’ prospective observational study comparing blood culture contamination rate and risk factors associated with contamination between ED and MICU/MHDU. A total of 998 patients were included in the study who underwent blood culture in ED and MICU/MHDU. 570 in ED and 428 in MICU/MHDU were included after meeting exclusion and inclusion criteria. Results: Blood culture growths were higher in ED (19%). Most common growth was CoNS (4%). The overall contamination rate in this study was (4.8%) The contamination rate was lower in ED (4.4%) when compared to MICU/MHDU (5.4%).

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Risk factors for opioid‐related adverse drug events among older adults after hospital discharge

Journal of the American Geriatrics Society ◽

10.1111/jgs.17453 ◽

2021 ◽

Author(s):

Shoshana J. Herzig ◽

Timothy S. Anderson ◽

Yoojin Jung ◽

Long H. Ngo ◽

Ellen P. McCarthy

Keyword(s):

Risk Factors ◽

Older Adults ◽

Hospital Discharge ◽

Adverse Drug Events

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P3-474: OBJECTIVE CARDIOMETABOLIC DEMENTIA-RELATED RISK FACTORS ASSOCIATED WITH FUNCTIONAL BRAIN ACTIVITY IN OLDER ADULTS: AN EVENT-RELATED POTENTIAL STUDY

Alzheimer s & Dementia ◽

10.1016/j.jalz.2019.06.3509 ◽

2019 ◽

Vol 15 ◽

pp. P1149-P1149

Author(s):

Hannah Keage ◽

Daniel Feuerriegel ◽

Danielle Greaves ◽

Emma Tregoweth ◽

Scott Coussens ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Brain Activity ◽

Event Related Potential ◽

Functional Brain ◽

Factors Associated ◽

Potential Study ◽

Related Risk ◽

Functional Brain Activity

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Factors Associated With Multimorbidity Patterns in Older Adults in England: Findings From the English Longitudinal Study of Aging (ELSA)

Journal of Aging and Health ◽

10.1177/0898264319891026 ◽

2019 ◽

Vol 32 (9) ◽

pp. 1120-1132 ◽

Cited By ~ 1

Author(s):

Hai Nguyen ◽

Kia-Chong Chua ◽

Alexandru Dregan ◽

Silia Vitoratou ◽

Ivet Bayes-Marin ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Longitudinal Study ◽

Latent Class ◽

Future Research ◽

Factors Associated ◽

Lifestyle Risk Factors ◽

Class B ◽

Lifestyle Risk ◽

English Longitudinal Study

Objective: We aimed to identify the patterns of multimorbidity in older adults and explored their association with sociodemographic and lifestyle risk factors. Method: The sample included 9,171 people aged 50+ from Wave 2 of the English Longitudinal Study of Aging (ELSA). Latent Class Analysis (LCA) was performed on 26 chronic diseases to determine clusters of common diseases within individuals and their association with sociodemographic and lifestyle risk factors. Result: Three latent classes were identified: (a) a cardiorespiratory/arthritis/cataracts class, (b) a metabolic class, and (c) a relatively healthy class. People aged 70 to 79 were 9.91 times (95% Confidence Interval [CI] = [5.13, 19.13]) more likely to be assigned to the cardiorespiratory/arthritis/cataracts class, while regular drinkers and physically inactive people were 0.33 times (95% CI = [0.24, 0.47]) less likely to be assigned to this class. Conclusion: Future research should investigate these patterns further to gain more insights into the needs of people with multimorbidity.

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Risk Factors of Recurrent Falls Among Older Adults Admitted to the Trauma Surgery Department

Geriatric Orthopaedic Surgery & Rehabilitation ◽

10.1177/2151459320943165 ◽

2020 ◽

Vol 11 ◽

pp. 215145932094316

Author(s):

William Curran-Groome ◽

Gary Klein ◽

Stanton B. Miller ◽

Azor Hui ◽

Jordan S. Wilson ◽

...

Keyword(s):

Risk Factors ◽

Older Adults ◽

Emergency Department ◽

Older Adult ◽

Trauma Surgery ◽

Intervention Strategies ◽

Medical Attention ◽

Recurrent Falls ◽

Surgery Department ◽

First 90 Days

Falls affect more than 29 million American adults ages ≥65 years annually. Many older adults experience recurrent falls requiring medical attention. These recurrent falls may be prevented through screening and intervention. In 2014 to 2015, records for 199 older adult patients admitted from a major urban teaching hospital’s emergency department were queried. Open-ended variables from clinicians’ notes were coded to supplement existing closed-ended variables. Of the 199 patients, 52 (26.1%) experienced one or more recurrent falls within 365 days after their initial fall. Half (50.0%) of all recurrent falls occurred within the first 90 days following discharge. A large proportion of recurrent falls among older adults appear to occur within a few months and are statistically related to identifiable risk factors. Prevention and intervention strategies, delivered either during treatment for an initial fall or upon discharge from an inpatient admission, may reduce the incidence of recurrent falls among this population.

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Status Epilepticus among Older Adults in the United States

Geriatrics ◽

10.3390/geriatrics4030045 ◽

2019 ◽

Vol 4 (3) ◽

pp. 45 ◽

Cited By ~ 1

Author(s):

Priya Mendiratta ◽

Neeraj Dayama ◽

Jeanne Y Wei ◽

Pallavi Prodhan ◽

Parthak Prodhan

Keyword(s):

Risk Factors ◽

Older Adults ◽

Ischemic Stroke ◽

Status Epilepticus ◽

Age Group ◽

Brain Hemorrhage ◽

Factors Associated ◽

Hospitalized Elderly ◽

Risk Of Mortality ◽

Overall Mortality

Objective: This study aimed to identify temporal time trends and risk factors associated with mortality for hospitalized older adults with status epilepticus (SE). Design: A retrospective study was performed. Setting: Hospitalized patients were identified utilizing an administrative database—The Nationwide Inpatient Sample database from 1998 through September 2015. Patients: Patients were older adults 65 years and older with SE. Interventions: No interventions were undertaken. Measurements and Main Results: Demographic, temporal trends, clinical characteristics, and outcome data were abstracted. The results indicated that hospitalized elderly Americans with SE increased over the 11-year study period. Univariate and multivariate analyses were performed to evaluate risk factors associated with mortality in the study cohort. From the weighted sample, 130,109 subjects were included. Overall mortality was 19%. For age subgroups, the mortality was highest for the >85 years age group (24.1%) compared to the 65–75 years (19%) and 75–85 years (23%) age groups. Among investigated etiologies, the three most common causes of SE were acute ischemic stroke (11.2% of total) followed by non-traumatic brain hemorrhage (5.4%) and malignant brain lesions (4.9%). The highest mortality by etiology was noted for acute traumatic brain injury (TBI) (31.5%), non-traumatic brain hemorrhage (31%), and acute ischemic stroke (AIS) (30.1%). Multivariate analysis indicated that non-survivors when compared to survivors were more like to have the following characteristics: older age group, acute TBI, brain neoplasms, non-traumatic brain hemorrhage, AIS and central nervous system (CNS) infections, and utilization of mechanical ventilation. Associated conditions significantly increasing risk of mortality were sodium imbalance, cardiac arrest, anoxic brain injury, pneumonia, and sepsis. Comorbidities associated with increased risk of mortality included valvular heart disease, renal failure, liver disease, and neoplasms. Conclusions: The number of hospitalized elderly Americans with SE increased over the 11-year study period. Overall mortality was 19%, with even higher mortality among various patient subsets. Several demographic and co-morbid factors are associated with increased mortality in this age group.

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