Synthesis and characterization of Cu(II)-based anticancer chemotherapeutic agent targeting topoisomerase Iα: In vitro DNA binding, pBR322 cleavage, molecular docking studies and cytotoxicity against human cancer cell lines

2014 ◽  
Vol 74 ◽  
pp. 509-523 ◽  
Author(s):  
Sartaj Tabassum ◽  
Mehvash Zaki ◽  
Mohd. Afzal ◽  
Farukh Arjmand
Keyword(s):  
Molecular Docking ◽  
Dna Binding ◽  
Chemotherapeutic Agent ◽  
Human Cancer ◽  
Docking Studies ◽  
Synthesis And Characterization ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

A saccharinate-bridged palladacyclic dimer with a Pd–Pd bond: experimental and molecular docking studies of the interaction with DNA and BSA and in vitro cytotoxicity against human cancer cell lines

2018 ◽  
Vol 42 (1) ◽  
pp. 574-586 ◽  
Author(s):  
Kazem Karami ◽  
Moloud Alinaghi ◽  
Zahra Amirghofran ◽  
Janusz Lipkowski ◽  
Amir Abbas Momtazi-borojeni
Keyword(s):  
Molecular Docking ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Biological Activities ◽  
Docking Studies ◽  
In Vitro Cytotoxicity ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

The synthesis, characterization and biological activities of a saccharinate-bridged palladacyclic dimer are reported in this work.

Copper(ii) complexes with benzhydrazone-related ligands: synthesis, structural studies and cytotoxicity assay

2017 ◽  
Vol 41 (6) ◽  
pp. 2425-2435 ◽  
Author(s):  
Marina Cindrić ◽  
Alen Bjelopetrović ◽  
Gordana Pavlović ◽  
Vladimir Damjanović ◽  
Jasna Lovrić ◽  
...  
Keyword(s):  
Cytotoxic Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Synthesis And Characterization ◽  
Structural Studies ◽  
Human Cancer Cell ◽  
Human Cancer Cell Lines

The present study reports the synthesis and characterization of copper(ii) complexes with benzhydrazone-related ligands. They were screened for their cytotoxic activityin vitroin THP-1 and HepG2 human cancer cell lines.

scholarly journals Purification and Characterization of a Lectin from Arisaema tortuosum Schott Having in-vitro Anticancer Activity against Human Cancer Cell Lines

BMB Reports ◽  
2005 ◽  
Vol 38 (5) ◽  
pp. 526-532 ◽  
Author(s):  
Vikram Dhuna ◽  
Jagmohan Singh Bains ◽  
Sukhdev Singh Kamboj ◽  
Jatinder Singh ◽  
Shanmugavel ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Cancer Cell Lines ◽  
Human Cancer Cell ◽  
Purification And Characterization ◽  
Human Cancer Cell Lines

Synthesis and characterization of steroidal heterocyclic compounds, DNA condensation and molecular docking studies and their in vitro anticancer and acetylcholinesterase inhibition activities

RSC Advances ◽  
2015 ◽  
Vol 5 (93) ◽  
pp. 75964-75984 ◽  
Author(s):  
Abad Ali ◽  
Mohd Asif ◽  
Hena Khanam ◽  
Ashraf Mashrai ◽  
Mohd Asif Sherwani ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Docking Studies ◽  
Dna Condensation ◽  
Acetylcholinesterase Inhibition ◽  
Synthesis And Characterization ◽  
Efficient Approach

A facile and efficient approach for the synthesis of steroidal heterocyclic compounds (4–12) has been performed. Furthermore, these newly synthesized compounds were evaluated for their various biological activities.

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