Recent progress in small molecule agents for the targeted therapy of triple-negative breast cancer

2020 ◽  
Vol 207 ◽  
pp. 112812
Author(s):  
Rajibul Islam ◽  
Kok Wai Lam
Keyword(s):  
Breast Cancer ◽  
Targeted Therapy ◽  
Small Molecule ◽  
Triple Negative Breast Cancer ◽  
Recent Progress ◽  
Triple Negative

64Cu/177Lu-DOTA-diZD, a Small-Molecule-Based Theranostic Pair for Triple-Negative Breast Cancer

2021 ◽  
Author(s):  
Yuqian Huang ◽  
Zhen Yang ◽  
Feng Li ◽  
Hong Zhao ◽  
Chun Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Small Molecule ◽  
Triple Negative Breast Cancer ◽  
Triple Negative

scholarly journals Pathogenesis and Potential Therapeutic Targets for Triple-Negative Breast Cancer

Cancers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 2978
Author(s):  
Chia-Jung Li ◽  
Yen-Dun Tony Tzeng ◽  
Yi-Han Chiu ◽  
Hung-Yu Lin ◽  
Ming-Feng Hou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Targeted Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
High Efficiency ◽  
Early Recurrence ◽  
New Developments ◽  
Great Progress ◽  
Low Toxicity ◽  
Made In

Triple negative breast cancer (TNBC) is a heterogeneous tumor characterized by early recurrence, high invasion, and poor prognosis. Currently, its treatment includes chemotherapy, which shows a suboptimal efficacy. However, with the increasing studies on TNBC subtypes and tumor molecular biology, great progress has been made in targeted therapy for TNBC. The new developments in the treatment of breast cancer include targeted therapy, which has the advantages of accurate positioning, high efficiency, and low toxicity, as compared to surgery, radiotherapy, and chemotherapy. Given its importance as cancer treatment, we review the latest research on the subtypes of TNBC and relevant targeted therapies.

Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions

2021 ◽  
Vol 64 (5) ◽  
pp. 2382-2418 ◽  
Author(s):  
Minru Liao ◽  
Jin Zhang ◽  
Guan Wang ◽  
Leiming Wang ◽  
Jie Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Discovery ◽  
Small Molecule ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Current Situation ◽  
Future Directions ◽  
Small Molecule Drug

scholarly journals The recent progress of neoadjuvant chemotherapy in triple negative breast cancer: A short review

2015 ◽  
Vol 5 (2) ◽  
Author(s):  
Michalis Liontos ◽  
Sophia Karageorgopoulou ◽  
Vasiliki Michalaki ◽  
John Contis ◽  
Evangelos Bournakis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Triple Negative Breast Cancer ◽  
Recent Progress ◽  
Triple Negative ◽  
Short Review

scholarly journals Recent Progress in Triple Negative Breast Cancer Research

2016 ◽  
Vol 17 (4) ◽  
pp. 1595-1608 ◽  
Author(s):  
Fatima Zahra Mouh ◽  
Mohammed El Mzibri ◽  
Meriem Slaoui ◽  
Mariam Amrani
Keyword(s):  
Breast Cancer ◽  
Cancer Research ◽  
Triple Negative Breast Cancer ◽  
Recent Progress ◽  
Triple Negative ◽  
Breast Cancer Research

scholarly journals Aptamer targeted therapy potentiates immune checkpoint blockade in triple-negative breast cancer

2020 ◽  
Vol 39 (1) ◽  
Author(s):  
Simona Camorani ◽  
Margherita Passariello ◽  
Lisa Agnello ◽  
Silvia Esposito ◽  
Francesca Collina ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Targeted Therapy ◽  
Triple Negative Breast Cancer ◽  
Immune Checkpoint ◽  
Triple Negative ◽  
Immune Checkpoint Blockade ◽  
Checkpoint Blockade
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