Clinical relevance validation of patient-specific anatomical models for surgical training powered by medical imaging

2021 ◽  
Vol 84 ◽  
pp. 299
Author(s):  
Florian Stefanov
Keyword(s):  
Medical Imaging ◽  
Surgical Training ◽  
Clinical Relevance ◽  
Patient Specific ◽  
Anatomical Models

Method for Incorporating Three-Dimensional Residual Stresses Into Patient-Specific Simulations of Arteries

2013 ◽  
Author(s):  
David M. Pierce ◽  
Thomas E. Fastl ◽  
Hannah Weisbecker ◽  
Gerhard A. Holzapfel ◽  
Borja Rodriguez-Vila ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Three Dimensional ◽  
Constitutive Models ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Abdominal Aortic ◽  
Model Geometry ◽  
Reconstructed Model

Through progress in medical imaging, image analysis and finite element (FE) meshing tools it is now possible to extract patient-specific geometries from medical images of, e.g., abdominal aortic aneurysms (AAAs), and thus to study clinically relevant problems via FE simulations. Medical imaging is most often performed in vivo, and hence the reconstructed model geometry in the problem of interest will represent the in vivo state, e.g., the AAA at physiological blood pressure. However, classical continuum mechanics and FE methods assume that constitutive models and the corresponding simulations start from an unloaded, stress-free reference condition.

scholarly journals Current Practice in Preoperative Virtual and Physical Simulation in Neurosurgery

2020 ◽  
Vol 7 (1) ◽  
pp. 7 ◽  
Author(s):  
Elisa Mussi ◽  
Federico Mussa ◽  
Chiara Santarelli ◽  
Mirko Scagnet ◽  
Francesca Uccheddu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
3D Printing ◽  
Surgical Planning ◽  
Physical Simulation ◽  
Planning Process ◽  
Preoperative Planning ◽  
Cost Effective ◽  
Patient Specific ◽  
Anatomical Models ◽  
Standard Clinical Practice

In brain tumor surgery, an appropriate and careful surgical planning process is crucial for surgeons and can determine the success or failure of the surgery. A deep comprehension of spatial relationships between tumor borders and surrounding healthy tissues enables accurate surgical planning that leads to the identification of the optimal and patient-specific surgical strategy. A physical replica of the region of interest is a valuable aid for preoperative planning and simulation, allowing the physician to directly handle the patient’s anatomy and easily study the volumes involved in the surgery. In the literature, different anatomical models, produced with 3D technologies, are reported and several methodologies were proposed. Many of them share the idea that the employment of 3D printing technologies to produce anatomical models can be introduced into standard clinical practice since 3D printing is now considered to be a mature technology. Therefore, the main aim of the paper is to take into account the literature best practices and to describe the current workflow and methodology used to standardize the pre-operative virtual and physical simulation in neurosurgery. The main aim is also to introduce these practices and standards to neurosurgeons and clinical engineers interested in learning and implementing cost-effective in-house preoperative surgical planning processes. To assess the validity of the proposed scheme, four clinical cases of preoperative planning of brain cancer surgery are reported and discussed. Our preliminary results showed that the proposed methodology can be applied effectively in the neurosurgical clinical practice both in terms of affordability and in terms of simulation realism and efficacy.

scholarly journals Innovációs lehetőségek a medicinában: 3D tervezési és 3D nyomtatási lehetőségek a felnőtt szív- és mellkassebészeti betegellátásban. Magyarországi tapasztalatok

2019 ◽  
Vol 160 (50) ◽  
pp. 1967-1975 ◽  
Author(s):  
János Imre Barabás ◽  
Áron Kristóf Ghimessy ◽  
Ferenc Rényi-Vámos ◽  
Ákos Kocsis ◽  
László Agócs ◽  
...  
Keyword(s):  
Clinical Case ◽  
Technology Development ◽  
3D Models ◽  
Patient Specific ◽  
Anatomical Models ◽  
Efficient Communication ◽  
The Common ◽  
Case Discussions ◽  
Procedural Planning ◽  
Surgery Department

Abstract: Use of 3D planning and 3D printing is expanding in healthcare. One of the common applications is the creation of anatomical models for the surgical procedure from DICOM files. These patient-specific models are used for multiple purposes, including visualization of complex anatomical situations, simulation of surgical procedures, patient education and facilitating communication between the different disciplines during clinical case discussions. Cardiac and thoracic surgical applications of this technology development include the use of patient-specific 3D models for exploration of ventricle and aorta function and surgical procedural planning in oncology. The 3D virtual and printed models provide a new visualization perspective for the surgeons and more efficient communication between the different clinical disciplines. The 3D project was started at the Semmelweis University with the cooperation of the Thoracic Surgery Department of the National Institute of Oncology in 2018. The authors want to share their experiences in 3D designed medical tools. Orv Hetil. 2019; 160(50): 1967–1975.

Custom Patient-Specific Three-Dimensional Printed Mitral Valve Models for Pre-Operative Patient Education Enhance Patient Satisfaction and Understanding

2019 ◽  
Vol 13 (3) ◽  
Author(s):  
Kay S. Hung ◽  
Michael J. Paulsen ◽  
Hanjay Wang ◽  
Camille Hironaka ◽  
Y. Joseph Woo
Keyword(s):  
Patient Education ◽  
Mitral Valve ◽  
Three Dimensional ◽  
3D Models ◽  
Patient Specific ◽  
Imaging Data ◽  
Anatomical Models ◽  
Mitral Valves ◽  
Flexible Polymer ◽  
3D Printed

In recent years, advances in medical imaging and three-dimensional (3D) additive manufacturing techniques have increased the use of 3D-printed anatomical models for surgical planning, device design and testing, customization of prostheses, and medical education. Using 3D-printing technology, we generated patient-specific models of mitral valves from their pre-operative cardiac imaging data and utilized these custom models to educate patients about their anatomy, disease, and treatment. Clinical 3D transthoracic and transesophageal echocardiography images were acquired from patients referred for mitral valve repair surgery and segmented using 3D modeling software. Patient-specific mitral valves were 3D-printed using a flexible polymer material to mimic the precise geometry and tissue texture of the relevant anatomy. 3D models were presented to patients at their pre-operative clinic visit and patient education was performed using either the 3D model or the standard anatomic illustrations. Afterward, patients completed questionnaires assessing knowledge and satisfaction. Responses were calculated based on a 1–5 Likert scale and analyzed using a nonparametric Mann–Whitney test. Twelve patients were presented with a patient-specific 3D-printed mitral valve model in addition to standard education materials and twelve patients were presented with only standard educational materials. The mean survey scores were 64.2 (±1.7) and 60.1 (±5.9), respectively (p = 0.008). The use of patient-specific anatomical models positively impacts patient education and satisfaction, and is a feasible method to open new opportunities in precision medicine.

Patient‐specific anatomical models for radioiodine dosimetry in treatment of hyperthyroidism: is it necessary?

2020 ◽  
Vol 47 (10) ◽  
pp. 5357-5365
Author(s):  
Susan Khalili ◽  
Hashem Miri‐Hakimabad ◽  
Elie Hoseinian‐Azghadi
Keyword(s):  
Patient Specific ◽  
Anatomical Models

scholarly journals Impact of Inflow Boundary Conditions on the Calculation of CT-Based FFR

Fluids ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 60 ◽  
Author(s):  
Ernest Lo ◽  
Leon Menezes ◽  
Ryo Torii
Keyword(s):  
Boundary Conditions ◽  
Coronary Arteries ◽  
Three Dimensional ◽  
Patient Specific ◽  
Fractional Flow ◽  
Anatomical Models ◽  
Diastolic Phase ◽  
Flow Reserve ◽  
Population Average ◽  
The Impact

Background: Calculation of fractional flow reserve (FFR) using computed tomography (CT)-based 3D anatomical models and computational fluid dynamics (CFD) has become a common method to non-invasively assess the functional severity of atherosclerotic narrowing in coronary arteries. We examined the impact of various inflow boundary conditions on computation of FFR to shed light on the requirements for inflow boundary conditions to ensure model representation. Methods: Three-dimensional anatomical models of coronary arteries for four patients with mild to severe stenosis were reconstructed from CT images. FFR and its commonly-used alternatives were derived using the models and CFD. A combination of four types of inflow boundary conditions (BC) was employed: pulsatile, steady, patient-specific and population average. Results: The maximum difference of FFR between pulsatile and steady inflow conditions was 0.02 (2.4%), approximately at a level similar to a reported uncertainty level of clinical FFR measurement (3–4%). The flow with steady BC appeared to represent well the diastolic phase of pulsatile flow, where FFR is measured. Though the difference between patient-specific and population average BCs affected the flow more, the maximum discrepancy of FFR was 0.07 (8.3%), despite the patient-specific inflow of one patient being nearly twice as the population average. Conclusions: In the patients investigated, the type of inflow boundary condition, especially flow pulsatility, does not have a significant impact on computed FFRs in narrowed coronary arteries.

Practical guidelines for fabricating mandibular guide flange prostheses: A new technique for measuring the flange angulation

2015 ◽  
Vol 40 (4) ◽  
pp. 528-531
Author(s):  
Farideh Geramipanah ◽  
Saman Fallahi Sichani ◽  
Susan Mirmohammadrezaei ◽  
Safoura Ghodsi
Keyword(s):  
Clinical Relevance ◽  
New Technique ◽  
Patient Specific ◽  
Posterior Teeth ◽  
Vertical Distance ◽  
Patient Will ◽  
Practical Guidelines ◽  
A New Technique

Background and aim: When a mandibulectomy causes discontinuity, the patient will need a rehabilitative prosthesis to achieve a proper occlusal relationship. Technique: This article describes step-by-step guidelines for measuring the patient-specific mandibular guide flange angulation. In the presented technique, the flange angulation is determined by dividing the horizontal overlap of the maxillary posterior teeth plus the maxillary buccal clasp thickness by the vertical distance of the mandibular continuous clasp up to the maxillary buccal clasp. Discussion: The mandibular guiding flange prosthesis must achieve an angulation that is appropriate for the particular circumstances of each patient to minimize the complications with mandibular deviation. Clinical relevance The introduced method for measuring the patient-specific mandibular guide flange angulation can help prosthodontists to prepare the mandibular guiding flange prosthesis with higher accuracy and predictability.

scholarly journals X Chromosome-Linked CNVs in Male Infertility: Discovery of Overall Duplication Load and Recurrent, Patient-Specific Gains with Potential Clinical Relevance

PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e97746 ◽  
Author(s):  
Chiara Chianese ◽  
Adam C. Gunning ◽  
Claudia Giachini ◽  
Fabrice Daguin ◽  
Giancarlo Balercia ◽  
...  
Keyword(s):  
Male Infertility ◽  
X Chromosome ◽  
Clinical Relevance ◽  
Patient Specific

scholarly journals From medical imaging data to 3D printed anatomical models

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0178540 ◽  
Author(s):  
Thore M. Bücking ◽  
Emma R. Hill ◽  
James L. Robertson ◽  
Efthymios Maneas ◽  
Andrew A. Plumb ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Imaging Data ◽  
Anatomical Models ◽  
3D Printed ◽  
Medical Imaging Data

scholarly journals Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment

2016 ◽  
Vol 56 (12) ◽  
pp. 1484-1499 ◽  
Author(s):  
Keith T. Schmidt ◽  
Cindy H. Chau ◽  
Douglas K. Price ◽  
William D. Figg
Keyword(s):  
Cancer Treatment ◽  
Clinical Relevance ◽  
Patient Specific ◽  
Precision Oncology
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