Influence of tumour suppressor gene (TP53, BRCA1 and BRCA2) polymorphisms on polycystic ovary syndrome in South Indian women

2018 ◽  
Vol 227 ◽  
pp. 13-18 ◽  
Author(s):  
Swapna Siddamalla ◽  
Tumu Venkat Reddy ◽  
Suresh Govatati ◽  
Praveen Guruvaiah ◽  
Mamata Deenadayal ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Suppressor Gene ◽  
Tumour Suppressor Gene ◽  
Tumour Suppressor ◽  
Brca1 And Brca2 ◽  
Ovary Syndrome ◽  
Indian Women ◽  
South Indian ◽  
Gene Tp53

Association of HSD11B1 rs12086634 and HSD11B1 rs846910 gene polymorphisms with polycystic ovary syndrome in South Indian women

2017 ◽  
Vol 38 (4) ◽  
pp. 381-386 ◽  
Author(s):  
Nayana Devang ◽  
Kapaettu Satyamoorthy ◽  
Padmalatha S. Rai ◽  
M. Nandini ◽  
Arindam Basu ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Gene Polymorphisms ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Indian Women ◽  
South Indian

scholarly journals An interleukin-6 gene promoter polymorphism is associated with polycystic ovary syndrome in South Indian women

2013 ◽  
Vol 30 (12) ◽  
pp. 1541-1546 ◽  
Author(s):  
Venkat Reddy Tumu ◽  
Suresh Govatati ◽  
Praveen Guruvaiah ◽  
Mamata Deenadayal ◽  
Sisinthy Shivaji ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Interleukin 6 ◽  
Polycystic Ovary ◽  
Gene Promoter ◽  
Promoter Polymorphism ◽  
Ovary Syndrome ◽  
Indian Women ◽  
South Indian ◽  
Gene Promoter Polymorphism

scholarly journals Distinct Genetic Susceptibility Patterns of the Obese and Non-obese South Indian Women with Polycystic Ovary Syndrome

2021 ◽  
Vol 21 (01) ◽  
Author(s):  
B. Mohan Reddy
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Genetic Susceptibility ◽  
Metabolic Pathway ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Indian Women ◽  
Regulatory Variants ◽  
South Indian ◽  
Susceptibility Patterns

The researchers studied association of 92 SNPs of the metabolic and reproductive pathways genes in the obesity related cohorts of obese PCOS cases and non-obese controls, and non-obese PCOS cases and non-obese controls and observed eleven SNPs to be significantly associated (p < 0.05). While eight of those SNPs, five from FTO and one each from MTCH2, DENNDIA and THADA genes, were found to be associated in the first set involving obese PCOS cases, only three SNPs (IRS2-intronic, LOC107984901-intergenic and SUMO1P1-regulatory variants) showed association in the 2nd set involving non-obese cases. The SNPs associated in the two cohorts were distinct and mutually exclusive. However, all the SNPs associated in either obese or non-obese PCOS cohorts were not only risk-prone but also broadly represented a metabolic pathway, involving mostly obesity and T2DM related genes, prompting one to surmise if the recent spurt in PCOS prevalence is not driven by changes in the lifestyles.

Polymorphisms in the IRS‐1 and PPAR-γ genes and their association with polycystic ovary syndrome among South Indian women

Gene ◽  
2012 ◽  
Vol 503 (1) ◽  
pp. 140-146 ◽  
Author(s):  
Shilpi Dasgupta ◽  
Pisapati Sirisha ◽  
Kudugunti Neelaveni ◽  
Katragadda Anuradha ◽  
Godi Sudhakar ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Indian Women ◽  
Ppar Γ ◽  
South Indian

scholarly journals Association of CAPN10 SNPs and Haplotypes with Polycystic Ovary Syndrome among South Indian Women

PLoS ONE ◽  
2012 ◽  
Vol 7 (2) ◽  
pp. e32192 ◽  
Author(s):  
Shilpi Dasgupta ◽  
Pisapati V. S. Sirisha ◽  
Kudugunti Neelaveni ◽  
Katragadda Anuradha ◽  
B. Mohan Reddy
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Indian Women ◽  
South Indian
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