Chronic administration of fluoxetine or clozapine induces oxidative stress in rat liver: A histopathological study

2014 ◽  
Vol 59 ◽  
pp. 20-30 ◽  
Author(s):  
Jelena Zlatković ◽  
Nevena Todorović ◽  
Nada Tomanović ◽  
Maja Bošković ◽  
Snežana Djordjević ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Chronic Administration ◽  
Histopathological Study

Glucocorticoid effects on respiration and metabolism by rat liver homogenates

1962 ◽  
Vol 202 (2) ◽  
pp. 343-346 ◽  
Author(s):  
Dennis D. Goetsch ◽  
L. E. McDonald
Keyword(s):  
Lactic Acid ◽  
Oxygen Uptake ◽  
Rat Liver ◽  
Inorganic Phosphate ◽  
Chronic Administration ◽  
Glucocorticoid Treatment ◽  
Carbohydrate Utilization ◽  
Protein Levels ◽  
Liver Homogenates ◽  
And Control

The effects of glucocorticoid administration on oxygen uptake, glucose and glycogen disappearance, lactic acid formation, and inorganic phosphate and protein levels in rat liver homogenates have been studied. A single injection of hydrocortisone, prednisolone, or 9 α-fluoroprednisolone 5 hr before sacrifice resulted in a highly significant increase in oxygen uptake by rat liver homogenates, whereas chronic administration of prednisolone daily for 7 days caused a marked inhibition in homogenate respiration. Glycolytic rate did not appear to be affected by single injections since endogenous carbohydrate utilization was similar in liver homogenates prepared from control and treated animals. Incubation of liver homogenates under aerobic conditions disclosed that inorganic phosphate levels were decreased in homogenates from corticoid-treated rats, whereas these levels were similar in treated and control liver homogenates incubated under nitrogen. Under anaerobic conditions, liver homogenates from treated rats accumulated lactic acid more rapidly than untreated liver homogenates. Glucocorticoid treatment did not appear to affect protein disappearance since no differences between protein levels in treated and untreated rat liver homogenates were detected following incubation.

Copper-Mediated Oxidative Stress in Rat Liver

2003 ◽  
Vol 96 (1-3) ◽  
pp. 209-216 ◽  
Author(s):  
Dervis Ozcelik ◽  
Resat Ozaras ◽  
Zafer Gurel ◽  
Hafize Uzun ◽  
Seval Aydin
Keyword(s):  
Oxidative Stress ◽  
Rat Liver

Ischaemic preconditioning on oxidative stress in an ex vivo perfused rat liver

2005 ◽  
Vol 22 (Supplement 34) ◽  
pp. 51
Author(s):  
V. Nuyens ◽  
Y. Kassar ◽  
J. Boogaerts ◽  
M. Stadler
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Ex Vivo ◽  
Perfused Rat Liver ◽  
Ischaemic Preconditioning

Oxidative stress-dependent contribution of HMGB1 to the interplay between apoptosis and autophagy in diabetic rat liver

2017 ◽  
Vol 73 (4) ◽  
pp. 511-521 ◽  
Author(s):  
Anja Petrović ◽  
Desanka Bogojević ◽  
Aleksandra Korać ◽  
Igor Golić ◽  
Sofija Jovanović-Stojanov ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Diabetic Rat ◽  
Stress Dependent

scholarly journals Evaluation of oxidative stress during apoptosis and necrosis caused by carbon tetrachloride in rat liver

2001 ◽  
Vol 1535 (2) ◽  
pp. 186-191 ◽  
Author(s):  
Fang Sun ◽  
Eri Hamagawa ◽  
Chihiro Tsutsui ◽  
Yoshiko Ono ◽  
Yukako Ogiri ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Carbon Tetrachloride ◽  
Rat Liver ◽  
Apoptosis And Necrosis

Possible Effects of Lycopene and Silymarin on Rat Liver Functions and Oxidative Stress Markers

2014 ◽  
Vol 39 (3) ◽  
pp. 344-350 ◽  
Author(s):  
Aysun Kilic Suloglu, PhD ◽  
Assoc. Prof. Gozde Girgin, PhD ◽  
Prof. Guldeniz Selmanoglu, PhD ◽  
Serdar Balci, MD ◽  
Prof. Terken Baydar, PhD
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Liver Functions ◽  
And Oxidative Stress
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