Measurement variations of MRI and CT in the assessment of tumor depth of invasion in oral cancer: A retrospective study

Background: Squamous cell carcinoma (SCC) of the oral tongue is characterized by a high propensity for cervical nodal metastasis, which affects the probability of regional control and survival. Many histopathologic parameters in tongue squamous cell carcinoma have been identified as predictive factors for cervical metastasis. Several studies focused on tumor thickness, and the depth of invasion was suggested to have a relationship to the occurrence of cervical metastasis.Methods: The medical records of 134 primary tongue carcinomas operated without any preoperative therapy. Author conducted a retrospective study of anterior tongue cancer cases operated at the institute in the department of surgery between April 2012 till March 2017 and studied the correlation between tumour thickness and nodal spread. Each patient's tumor type, tumor location, tumor size, invasion mode, depth of invasion, intralymphatic tumor emboli, and perineural invasion were evaluated.Results: The overall cervical metastatic rate was 56.71%. In the group in which tumor depth exceeded 5mm, the metastatic rate was 77.77% (70/90). In contrast, when the depth of invasion was less than 5mm, the incidence of cervical metastasis was 13.63% (6/44). Clinically negative necks turned out pathologically positive in 28.39%.Conclusions: It was observed that there is a discerning point at 5mm of tumor depth at which cervical metastasis is probable. Elective neck therapy (surgery or irradiation) is strongly indicated for tumors exceeding 5mm invasion.

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Preoperative evaluation of tumor depth of invasion in oral squamous cell carcinoma with intraoral ultrasonography: a retrospective study

Oral Surgery Oral Medicine Oral Pathology and Oral Radiology ◽

10.1016/j.oooo.2020.07.003 ◽

2021 ◽

Vol 131 (1) ◽

pp. 130-138

Author(s):

Federica Rocchetti ◽

Gianluca Tenore ◽

Alessandra Montori ◽

Andrea Cassoni ◽

Vito Cantisani ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Retrospective Study ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Preoperative Evaluation ◽

Depth Of Invasion ◽

Tumor Depth

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Classifying endocervical adenocarcinoma (EADC) by pattern correlates better with the presence or absence of lymph node (LN) metastasis than using tumor depth of invasion

Gynecologic Oncology ◽

10.1016/j.ygyno.2011.12.062 ◽

2012 ◽

Vol 125 ◽

pp. S27-S28

Author(s):

I. Alvarado-Cabrero ◽

K. Park ◽

G. Rasty ◽

S. Hong ◽

J. Chanona-Vilchis ◽

...

Keyword(s):

Lymph Node ◽

Depth Of Invasion ◽

Tumor Depth ◽

Endocervical Adenocarcinoma

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Histopathological spectrum of oral cavity lesions – A tertiary care experience

Indian Journal of Pathology and Oncology ◽

10.18231/j.ijpo.2021.071 ◽

2021 ◽

Vol 8 (3) ◽

pp. 364-368

Author(s):

Ishani Gupta ◽

Rekha Rani ◽

Jyotsna Suri

Keyword(s):

Squamous Cell Carcinoma ◽

Retrospective Study ◽

Oral Cancer ◽

Oral Cavity ◽

Cell Carcinoma ◽

Squamous Cell ◽

Tertiary Care ◽

Proper Management ◽

The World ◽

One Year

Oral cancer is one of a major health problem in some parts of the world especially in the developing countries. Oral cancer is the sixth most common cancer in the world whereas in India it is one of the most prevalent cancer. Oral cavity lesions are usually asymptomatic. Accurate diagnosis of the lesion is the first step for the proper management of patients and histopathology is considered as the gold standard. The objective is to study the different patterns of oral cavity lesions seen in a tertiary care hospital of Jammu: One year retrospective study. Post graduate department of pathology.: It was a retrospective study carried out in a tertiary care centre for a period of one year from March 2020 to Feb 2021. 148 cases of oral cavity lesions were included in this study. The parameters that were included in the study were sociodemographic data, site of the lesion, clinical features and histological diagnosis. Data collected was analysed.148 cases of oral lesions were identified during the period of study. The age of patients varied from 5 to 78years and Male to Female ratio was 2.2:1. Buccal mucosa (30%) was the most common site involved which was followed by tonsil (19%). Out of 148 cases 70 cases were malignant, 10 cases pre malignant and 21 cases were benign. Squamous cell carcinoma (33.7%) was the most common lesion present in our study. Oral cavity lesions have a vast spectrum of diseases which range from tumour like lesions to benign and malignant tumours. Our study concluded that squamous cell carcinoma was the most common malignant lesion of oral cavity. Histological typing of the lesion is important for confirmation of malignancy and it is essential for the proper management of the patient.

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