Catalytic gasification of algal biomass for hydrogen-rich gas production: Parametric optimization via central composite design

2018 ◽  
Vol 158 ◽  
pp. 235-245 ◽  
Author(s):  
Abdul Raheem ◽  
Guozhao Ji ◽  
Asif Memon ◽  
Siva Sivasangar ◽  
Wei Wang ◽  
...  
Keyword(s):  
Central Composite Design ◽  
Algal Biomass ◽  
Parametric Optimization ◽  
Gas Production ◽  
Catalytic Gasification ◽  
Central Composite

scholarly journals Solar-driven steam gasification of oil palm empty fruit bunch to produce syngas: Parametric optimization via central composite design

2022 ◽  
Vol 227 ◽  
pp. 107118
Author(s):  
Saqr A.A. Al-Muraisy ◽  
Lais Americo Soares ◽  
Srirat Chuayboon ◽  
Shahrul Bin Ismail ◽  
Stéphane Abanades ◽  
...  
Keyword(s):  
Central Composite Design ◽  
Oil Palm ◽  
Parametric Optimization ◽  
Steam Gasification ◽  
Empty Fruit Bunch ◽  
Central Composite

Development and optimization of solid lipid nanoparticles of amikacin by central composite design

2009 ◽  
Vol 00 (00) ◽  
pp. 090721051030036-8
Author(s):  
Jaleh Varshosaz ◽  
Solmaz Ghaffari ◽  
Mohammad Reza Khoshayand ◽  
Fatemeh Atyabi ◽  
Shirzad Azarmi ◽  
...  
Keyword(s):  
Central Composite Design ◽  
Solid Lipid Nanoparticles ◽  
Lipid Nanoparticles ◽  
Solid Lipid ◽  
Central Composite

Formulation Design and Optimization of Repaglinide Solid Dispersions by Central Composite Design

2018 ◽  
Vol 11 (6) ◽  
pp. 4337-4348
Author(s):  
Bhikshapathi D. V. R. N. ◽  
Srinivas I
Keyword(s):  
Central Composite Design ◽  
Dissolution Rate ◽  
Solid Dispersion ◽  
Solid Dispersions ◽  
Solvent Evaporation ◽  
Release Mechanism ◽  
Solvent Evaporation Method ◽  
Onset Of Action ◽  
Evaporation Method ◽  
Central Composite

Repaglinide is a pharmaceutical drug used for the treatment of type II diabetes mellitus, it is characterized with poor solubility which limits its absorption and dissolution rate and delays onset of action. In the present study, immediate release solid dispersion of repaglinide was formulated by solvent evaporation technique. Repaglinide solid dispersions were prepared using PEG 8000, Pluronic F 127 and Gelucire 44/14 by solvent evaporation method. A 3-factor, 3-level central composite design employed to study the effect of each independent variable on dependent variables. FTIR studies revealed that no drug excipient interaction takes place. From powder X-ray diffraction (p-XRD) and by scanning electron microscopy (SEM) studies it was evident that polymorphic form of repaglinide has been converted into an amorphous form from crystalline within the solid dispersion formulation. The correlation coefficient showed that the release profile followed Higuchi model anomalous behavior and hence release mechanism was indicative of diffusion. The obtained results suggested that developed solid dispersion by solvent evaporation method might be an efficacious approach for enhancing the solubility and dissolution rate of repaglinide.

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