High strength steel reinforced concrete (HSRC) column refers to steel reinforced concrete column using high strength steel with its yield strength over 420MPa. So far, research on seismic behavior of HSRC columns is limited. This paper presents experimental and numerical studies on seismic behavior of HSRC columns. Two Q460 high strength steel reinforced concrete columns have been tested under low cyclic loading with constant axial compression ratio of 0.3. Flexural failure is observed in the test. From the hysteresis curves, the specimens exhibit good ductility and satisfactory energy dissipation capacity. Displacement ductility factors are larger than 2. When load descends to 85% of the peak load, the ultimate drift ratios of two specimens are 1/29 and 1/26 respectively, which meet the requirements of Chinese Seismic Design code (GB 50011). To study the seismic behavior of HSRC columns more comprehensively, a numerical model has been established for simulating the experiment using OpenSees, which adopts nonlinear beam-column element and fiber model. The numerical result fits the test data well, which validates the effectiveness of numerical model. Parametric study is then carried out to further investigate the seismic behavior of HSRC columns.