Perfluoroalkyl acids (PFAAs) in the aquatic food web of a temperate urban lake in East China: Bioaccumulation, biomagnification, and probabilistic human health risk

2021 ◽  
pp. 118748
Author(s):  
Kejian Chu ◽  
Ying Lu ◽  
Zulin Hua ◽  
Yuanyuan Liu ◽  
Yixin Ma ◽  
...  
Toxins ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 83 ◽  
Author(s):  
Emilie Lance ◽  
Nathalie Arnich ◽  
Thomas Maignien ◽  
Ronel Biré

The neurotoxin β-N-methylamino-l-alanine (BMAA), a non-protein amino acid produced by terrestrial and aquatic cyanobacteria and by micro-algae, has been suggested to play a role as an environmental factor in the neurodegenerative disease Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia complex (ALS-PDC). The ubiquitous presence of BMAA in aquatic environments and organisms along the food chain potentially makes it public health concerns. However, the BMAA-associated human health risk remains difficult to rigorously assess due to analytical challenges associated with the detection and quantification of BMAA and its natural isomers, 2,4-diamino butyric acid (DAB), β-amino-N-methyl-alanine (BAMA) and N-(2-aminoethyl) glycine (AEG). This systematic review, reporting the current knowledge on the presence of BMAA and isomers in aquatic environments and human food sources, was based on a selection and a score numbering of the scientific literature according to various qualitative and quantitative criteria concerning the chemical analytical methods used. Results from the best-graded studies show that marine bivalves are to date the matrix containing the higher amount of BMAA, far more than most fish muscles, but with an exception for shark cartilage. This review discusses the available data in terms of their use for human health risk assessment and identifies knowledge gaps requiring further investigations.


2014 ◽  
Vol 490 ◽  
pp. 987-993 ◽  
Author(s):  
Zhi-Hao Wen ◽  
Ling Chen ◽  
Xiang-Zhou Meng ◽  
Yan-Ping Duan ◽  
Zeng-Sheng Zhang ◽  
...  

2006 ◽  
Vol 14 (2) ◽  
pp. 559-570 ◽  
Author(s):  
F. Quercia ◽  
A. Vecchio ◽  
M. Falconi ◽  
L. Togni ◽  
E. Wcislo ◽  
...  

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