The biodiversity of local plants on Phraek Nam Daeng community Amphawa, Samut Songkhram province, Thailand has been the result of the terrain as a source of freshwater and salty. This study was carried out to evaluate the phytochemical screening and nutritional value of 6 local plants in the Phraek Nam Daeng community including: Azima sarmentosa Benth, Pluchea indica (L) Less,, Boehravia diffusa L, Acanthus ilicifolius L, Sesuvium portulacastrum L and Derris trifoliata Lour. The phytochemical analysis was performed for alkaloid, tannin, terpenoid, flavonoid, anthraquinone and cardiac glycoside. Nutritional analysis of proximal composition of local plants using the method of AOAC (2005),Which consist of moisture content, protein content, lipid content, fiber content, total ash content and carbohydrate content. The results showed that phytochemical screening of 6 local plants, the methanolic extracts have the presence of bioactive substances such as alkaloid, tannin, terpenoid, flavonoid, anthraquinone and cardiac glycoside. The most nutritional composition of local plants showed that the moisture content was Sesuvium portulacastrum L, protein content was Acanthus ilicifolius L, lipid and carbohydrate content was Azima sarmentosa Benth. & Hook, fiber content was Pluchea indica (L) Less., these represent the potential of food crops for food security and sustainable use of biodiversity.