ADVERSE LIFE EVENTS, PSYCHIATRIC COMORBIDITY, AND BIOLOGICAL PREDICTORS OF POSTPARTUM DEPRESSION IN AN ETHNICALLY DIVERSE SAMPLE OF POSTPARTUM WOMEN

2019 ◽  
Vol 29 ◽  
pp. S907
Author(s):  
Jerry Guintivano ◽  
Patrick Sullivan ◽  
Alison Stuebe ◽  
Thomas Penders ◽  
John Thorp ◽  
...  
Keyword(s):  
Postpartum Depression ◽  
Life Events ◽  
Psychiatric Comorbidity ◽  
Ethnically Diverse ◽  
Postpartum Women ◽  
Adverse Life Events

893. Adverse Life Events, Psychiatric Comorbidity, and Biological Predictors of Postpartum Depression in an Ethnically Diverse Sample of Postpartum Women

2017 ◽  
Vol 81 (10) ◽  
pp. S360-S361
Author(s):  
Jerry Guintivano ◽  
Patrick Sullivan ◽  
Alison Stuebe ◽  
Thomas Penders ◽  
John Thorp ◽  
...  
Keyword(s):  
Postpartum Depression ◽  
Life Events ◽  
Psychiatric Comorbidity ◽  
Ethnically Diverse ◽  
Postpartum Women ◽  
Adverse Life Events

scholarly journals Adverse life events, psychiatric history, and biological predictors of postpartum depression in an ethnically diverse sample of postpartum women

2017 ◽  
Vol 48 (7) ◽  
pp. 1190-1200 ◽  
Author(s):  
J. Guintivano ◽  
P. F. Sullivan ◽  
A. M. Stuebe ◽  
T. Penders ◽  
J. Thorp ◽  
...  
Keyword(s):  
Postpartum Depression ◽  
Life Events ◽  
Low Income ◽  
Depression Scale ◽  
Genetic Ancestry ◽  
Self Report ◽  
Psychiatric History ◽  
Adverse Life Events ◽  
Multiple Exposures ◽  
Case Status

AbstractBackgroundRace, psychiatric history, and adverse life events have all been independently associated with postpartum depression (PPD). However, the role these play together in Black and Latina women remains inadequately studied. Therefore, we performed a case–control study of PPD, including comprehensive assessments of symptoms and biomarkers, while examining the effects of genetic ancestry.MethodsWe recruited our sample (549 cases, 968 controls) at 6 weeks postpartum from obstetrical clinics in North Carolina. PPD status was determined using the MINI-plus. Psychiatric history was extracted from medical records. Participants were administered self-report instruments to assess depression (Edinburgh Postnatal Depression Scale) and adverse life events. Levels of estradiol, progesterone, brain-derived neurotrophic factor, oxytocin, and allopregnanalone were assayed. Principal components from genotype data were used to estimate genetic ancestry and logistic regression was used to identify predictors of PPD.ResultsThis population was racially diverse (68% Black, 13% Latina, 18% European). Genetic ancestry was not a predictor of PPD. Case status was predicted by a history of major depression (p= 4.01E-14), lifetime anxiety disorder diagnosis (p= 1.25E-34), and adverse life events (p= 6.06E-06). There were no significant differences between groups in any hormones or neurosteroids.ConclusionsPsychiatric history and multiple exposures to adverse life events were significant predictors of PPD in a population of minority and low-income women. Genetic ancestry and hormone levels were not predictive of case status. Increased genetic vulnerability in conjunction with risk factors may predict the onset of PPD, whereas genetic ancestry does not appear predictive.

The Assessment Of Postpartum Depression In Ethnically Diverse Women

2002 ◽  
Author(s):  
Rhonda C. Boyd ◽  
Evelyn L. Barbee ◽  
Golda S. Ginsburg ◽  
Kimberly A. Yonkers ◽  
JaneL. Pearson
Keyword(s):  
Postpartum Depression ◽  
Ethnically Diverse

scholarly journals Postpartum depression symptoms in survey-based research: a structural equation analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Che Wan Jasimah Bt Wan Mohamed Radzi ◽  
Hashem Salarzadeh Jenatabadi ◽  
Nadia Samsudin
Keyword(s):  
Postpartum Depression ◽  
Latent Variable ◽  
Structural Equation ◽  
Depression Scale ◽  
Public Health Problem ◽  
Equation Modeling ◽  
Depression Symptoms ◽  
Postpartum Women ◽  
Unhealthy Food ◽  
High Level

Abstract Background Since the last decade, postpartum depression (PPD) has been recognized as a significant public health problem, and several factors have been linked to PPD. Mothers at risk are rarely undetected and underdiagnosed. Our study aims to determine the factors leading to symptoms of depression using Structural Equation Modeling (SEM) analysis. In this research, we introduced a new framework for postpartum depression modeling for women. Methods We structured the model of this research to take into consideration the Malaysian culture in particular. A total of 387 postpartum women have completed the questionnaire. The symptoms of postpartum depression were examined using the Edinburgh Postnatal Depression Scale (EPDS), and they act as a dependent variable in this research model. Results Four hundred fifty mothers were invited to participate in this research. 86% of the total distributed questionnaire received feedback. The majority of 79.6% of respondents were having depression symptoms. The highest coefficients of factor loading analysis obtained in every latent variable indicator were income (β = 0.77), screen time (β = 0.83), chips (β = 0.85), and anxiety (β = 0.88). Lifestyle, unhealthy food, and BMI variables were directly affected by the dependent variable. Based on the output, respondents with a high level of depression symptoms tended to consume more unhealthy food and had a high level of body mass indexes (BMI). The highest significant impact on depression level among postpartum women was unhealthy food consumption. Based on our model, the findings indicated that 76% of the variances stemmed from a variety of factors: socio-demographics, lifestyle, healthy food, unhealthy food, and BMI. The strength of the exogenous and endogenous variables in this research framework is strong. Conclusion The prevalence of postpartum women with depression symptoms in this study is considerably high. It is, therefore, imperative that postpartum women seek medical help to prevent postpartum depressive symptoms from worsening.

scholarly journals Experienced Adversity in Life Is Associated With Polarized and Affirmed Political Attitudes

2017 ◽  
Vol 8 (6) ◽  
pp. 652-659 ◽  
Author(s):  
Daniel Randles ◽  
Steven J. Heine ◽  
Michael Poulin ◽  
Roxane Cohen Silver
Keyword(s):  
Life Events ◽  
Positive Relationship ◽  
Political Attitudes ◽  
Secondary Analysis ◽  
National Sample ◽  
Adverse Life Events ◽  
Over Time

Many studies find that when made to feel uncertain, participants respond by affirming importantly held beliefs. However, while theories argue that these effects should persist over time for highly disruptive experiences, almost no research has been performed outside the lab. We conducted a secondary analysis of data from a national sample of U.S. adults ( N = 1,613) who were followed longitudinally for 3 years. Participants reported lifetime and recent adversities experienced annually, as well as their opinions on a number of questions related to intergroup hostility and aggression toward out-groups, similar to those used in many lab studies of uncertainty. We anticipated that those who had experienced adversity would show more extreme support for their position. There was a positive relationship between adversity and the tendency to strongly affirm and polarize their positions. Results suggest that adverse life events may lead to long-lasting changes in one’s tendency to polarize one’s political attitudes.

scholarly journals The Connections of Pregnancy-, Delivery-, and Infant-Related Risk Factors and Negative Life Events on Postpartum Depression and Their Role in First and Recurrent Depression

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Pirjo Kettunen ◽  
Eeva Koistinen ◽  
Jukka Hintikka
Keyword(s):  
Risk Factors ◽  
Postpartum Depression ◽  
Life Events ◽  
Negative Life Events ◽  
Control Group ◽  
Recurrent Depression ◽  
Physical Problems ◽  
Adverse Experiences ◽  
Breastfeeding Cessation ◽  
Axis I

Introduction. The aim of this study is to assess how negative life events and adverse experiences with pregnancy, delivery, the infant(s), and breastfeeding cessation impact on postpartum depression (PPD), specifically in first lifetime and recurrent depression. Method. The study group comprised 104 mothers with a current episode of PPD and a control group of 104 mothers who did not have current PPD. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) was used for data collection. The course of the depression, adverse experiences, and breastfeeding were assessed by self-reports. Results. In age-adjusted multivariate analyses, mental and physical problems during pregnancy or delivery, postpartum problems with the infant and breastfeeding cessation, and negative life events during the previous 12 months were associated with postpartum depression. Eighteen percent (18%) of the mothers had first depression and 82% recurrent depression. Mental and physical problems during pregnancy or delivery were associated with both first lifetime and recurrent depression. Nevertheless, negative life events and infant/breastfeeding issues associated only with recurrent depression. Conclusion. Factors associated with pregnancy and delivery have an impact on PPD, but in recurrent depression other postnatal and psychosocial factors are also important risk factors.

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