P.0271 Association of polymorphic marker val158met of comt gene with depression in an open population 25-44 years: epidemiological study

2021 ◽  
Vol 53 ◽  
pp. S195-S196
Author(s):  
V. Gafarov ◽  
E. Gromova ◽  
D. Panov ◽  
I. Gagulin ◽  
V. Maximov ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Polymorphic Marker ◽  
Comt Gene ◽  
Open Population

Association of depression with polymorphic marker Val158Met of COMT gene in an open population 25–44 years: Epidemiological study

2021 ◽  
Vol 429 ◽  
pp. 118281
Author(s):  
Valery Gafarov ◽  
Elena Gromova ◽  
Dmitriy Panov ◽  
Igor Gagulin ◽  
Vladimir Maximov ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Polymorphic Marker ◽  
Comt Gene ◽  
Open Population

scholarly journals Prevalence of ischemic heart disease depending on factors of psychoemotional stress among men of mature age (epidemiological study)

2021 ◽  
Vol 93 (1) ◽  
pp. 25-29
Author(s):  
Ekaterina V. Akimova ◽  
Mikhail Y. Akimov ◽  
Marina M. Kayumova ◽  
Valery V. Gafarov
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Epidemiological Study ◽  
Emotional Stress ◽  
Stress Factors ◽  
Ischemic Heart ◽  
Psychoemotional Stress ◽  
Open Population ◽  
Conventional Risk Factors

Aim. To establish associations of the prevalence of ischemic heart disease (IHD) and factors of psychoemotional stress in men of the open urban population in the age group 4564 years after two decades of life. Materials and methods. A cross-sectional epidemiological study using a model of the city of Tyumen was conducted on a representative sample of the population among males of mature age (4564 years). Based on standard epidemiological methods, IHD was established according to strict epidemiological criteria definite IHD. The study of the factors of psycho-emotional stress (depression, hostility, life exhaustion) was carried out according to the algorithms of the World Health Organization program MONICA-psychosocial. When calculating the odds ratio for the development of IHD, a low level of psycho-emotional stress factors was regarded as the absence of a sign, a combination of medium and high levels as a presence. Results. The prevalence of ischemic heart disease in the open population (on the model of Tyumen) according to strict epidemiological criteria in men aged 4554 years was 8.2%, at the age of 5564 years 19.2%, a predominance of painless form of ischemic heart disease was revealed. According to the levels of factors of psychoemotional stress in mature men, mainly the average level of depression and life exhaustion, a high level of hostility were established. In men of an open population (on the model of Tyumen), depending on the psychoemotional stress, a high risk of developing a certain coronary heart disease was established in the age categories 4554 and 5564 years old in the presence of depression, at the age of 5564 years in the presence of hostility or life exhaustion. Conclusion. Consequently, the data obtained indicate the importance of further studying the factors of psychoemotional stress in men of mature age in Siberian populations, their relationships with conventional risk factors for coronary artery disease, as well as the advisability of preventive measures aimed at weakening the influence of not only conventional risk factors, but also factors of psycho-emotional stress. among the Russian population.

scholarly journals ASSOCIATIONS OF WORK STRESS AND CORONARY ARTERY DISEASE IN AN OPEN POPULATION MODEL

2018 ◽  
Vol 7 (4) ◽  
pp. 70-76
Author(s):  
E. V. Akimova ◽  
M. I. Bessonova ◽  
V. V. Gafarov
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Epidemiological Study ◽  
Work Stress ◽  
Population Model ◽  
Single Step ◽  
Open Population ◽  
Stress Components ◽  
Working Age ◽  
Artery Disease

Aim. To determine the relationships between the prevalence of certain work stress components and coronary artery disease in men of working age in the open population model of the medium-urbanized Siberian city (Tyumen).Methods. A single-step epidemiological study was performed using the open population model with a representative sample of male adults (25–64 years) living in the Central Tyumen Administrative District. The subjects were stratifed by age (1000 men, 85.0% response rate). The data on coronary artery disease (CAD) were collected with the standard methods commonly used in the epidemiological studies. Work stress was determined with the questionnaire used in the WHO MONICA psychosocial program.Results. Over 85% of men showed signifcant changes in work during the last year in the male unorganized population of the mid-urbanized Siberian city. Lower responsibility and workload, as well as an increase in the negative attitude towards work have been found in male adults with CAD aged 25–64.Conclusion. The single-step epidemiological study with the open male population model of the mid-urbanized Siberian city showed the presence of the associations between the prevalence of CAD and some work stress components (physical activity and work responsibility within the last 12 months). The obtained results can be furtherly used for the development and implementation of socially oriented comprehensive prevention programs aimed at improving work environment for the personnel, including both, healthy subjects and working age men with CAD.

Polymorphism of the comt gene and vital exhaustion in open population of 45–64 years. International epidemiological programs: Who MONICA, HAPIEE

2019 ◽  
Vol 405 ◽  
pp. 67-68
Author(s):  
V. Gafarov ◽  
E. Gromova ◽  
D. Panov ◽  
I. Gagulin ◽  
A. Gafarova ◽  
...  
Keyword(s):  
Comt Gene ◽  
Vital Exhaustion ◽  
Open Population

scholarly journals Clinical-epidemiological study of leptospirosis in humans and reservoirs in Yucatán, México

2002 ◽  
Vol 44 (6) ◽  
pp. 335-340 ◽  
Author(s):  
Ignacio VADO-SOLÍS ◽  
María F. CÁRDENAS-MARRUFO ◽  
Bertha JIMÉNEZ-DELGADILLO ◽  
Alejandro ALZINA-LÓPEZ ◽  
Hugo LAVIADA-MOLINA ◽  
...  
Keyword(s):  
Epidemiological Study ◽  
Rural Areas ◽  
Agglutination Test ◽  
The State ◽  
Serious Illness ◽  
Human Antibodies ◽  
Open Population ◽  
Animal Reservoirs ◽  
Made In ◽  
Significant Factors

A leptospirosis clinical-epidemiological study was made in humans and reservoirs in the state of Yucatán, México. Interviews and serological analyses were made on 400 persons from an open population, 439 probable cases of leptospirosis and 1060 animal reservoirs (cows, pigs, dogs, rats and opossums). IgM Leptospira DipstickTM and Microscopic Agglutination Test (MAT) was used to detect human antibodies to leptospiras and serovar respectively. Leptospirosis incidence in humans was 2.2/100,000 inhab. in 1998, 0.7/100,000 in 1999 and 0.9/100,000 in 2000. Overall seroprevalence was 14.2%, relatively unchanged from seroprevalences observed 20 years ago. Highest seropositivity was found in people over 56 years of age, predominating males over females. Predominant serovars in the open population were tarassovi, hardjo, pomona and panama. Leptospirosis cases were most frequent in rural areas, and the anicteric course predominated over the icteric. The panama, icterohaemorrhagiae and pomona serovars predominated in both anicteric and icteric courses. Dogs, pigs and rodents had the highest seropositivity among the reservoirs. Contact with rodents and natural water sources were significant factors (p <FONT FACE=Symbol>£</FONT> 0.05). Human cases (74%) occurred during the rainy season. It is concluded that leptospirosis is still a serious illness with important clinical and epidemiological implications in the state of Yucatán, Mexico.

Incidence and natural history of HCV infection in Northern Italy: Results of an epidemiological study

2001 ◽  
Vol 120 (5) ◽  
pp. A366-A366
Author(s):  
C MAZZEO ◽  
F AZZAROLI ◽  
A COLECCHIA ◽  
S DISILVIO ◽  
A DORMI ◽  
...  
Keyword(s):  
Natural History ◽  
Epidemiological Study ◽  
Northern Italy ◽  
Hcv Infection ◽  
History Of
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