Enzyme responsive self-assembled amphiphilic diblock copolymer synthesized by the combination of NMP and macromolecular azo coupling reaction

A novel amphiphilic diblock copolymer containing cyclic-azobenzene has been synthesized and self-assembled into spherical micelles which show unusual photo-responsive behaviors.

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Biodegradable self-assembled nanoparticles of PEG-PLGA amphiphilic diblock copolymer as a promising stealth system for augmented vinpocetine brain delivery

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2020.119778 ◽

2020 ◽

Vol 588 ◽

pp. 119778

Author(s):

Osama A.A. Ahmed ◽

Shaimaa M. Badr-Eldin

Keyword(s):

Diblock Copolymer ◽

Brain Delivery ◽

Amphiphilic Diblock Copolymer ◽

Self Assembled

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Excited-state dynamics of an amphiphilic diblock copolymer self-assembled from mixed solvents

Polymer ◽

10.1016/j.polymer.2016.07.011 ◽

2016 ◽

Vol 99 ◽

pp. 122-129 ◽

Cited By ~ 2

Author(s):

Dongki Lee ◽

Joon Ki Kim ◽

Du-Jeon Jang

Keyword(s):

Excited State ◽

Diblock Copolymer ◽

Mixed Solvents ◽

Amphiphilic Diblock Copolymer ◽

Excited State Dynamics ◽

Self Assembled

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Synthesis and complex self-assembly of amphiphilic block copolymers with a branched hydrophobic poly(2-oxazoline) into multicompartment micelles, pseudo-vesicles and yolk/shell nanoparticles

Polymer Chemistry ◽

10.1039/c9py01559k ◽

2020 ◽

Vol 11 (6) ◽

pp. 1237-1248 ◽

Cited By ~ 8

Author(s):

Davy Daubian ◽

Jens Gaitzsch ◽

Wolfgang Meier

Keyword(s):

Block Copolymers ◽

Diblock Copolymer ◽

Self Assembly ◽

Amphiphilic Block Copolymers ◽

Side Chain ◽

Shell Nanoparticles ◽

Amphiphilic Diblock Copolymer ◽

Self Assembled ◽

Multicompartment Micelles

A new PEO-b-PEHOx amphiphilic diblock copolymer was achieved which unlocked new complex self-assembled structures. Thanks to its hydrophobic oxazoline block with a long branched side chain, EHOx, various potent structures were obtained.

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5-((8-Hydroxyquinolin-5-yl)diazenyl)-3-methyl-1H-pyrazole-4-carboxylic Acid

Molbank ◽

10.3390/m1238 ◽

2021 ◽

Vol 2021 (2) ◽

pp. M1238

Author(s):

Ion Burcă ◽

Valentin Badea ◽

Calin Deleanu ◽

Vasile-Nicolae Bercean

Keyword(s):

Chemical Structure ◽

Functional Group ◽

Coupling Reaction ◽

2D Nmr ◽

Azo Coupling ◽

2D Nmr Spectroscopy ◽

Azo Compound ◽

Ft Ir ◽

New Compounds ◽

Carboxylic Functional Group

A new azo compound was prepared via the azo coupling reaction between 4-(ethoxycarbonyl)-3-methyl-1H-pyrazole-5-diazonium chloride and 8-hydroxyquinoline (oxine). The ester functional group of the obtained compound was hydrolyzed and thus a new chemical structure with a carboxylic functional group resulted. The structures of the new compounds were fully characterized by: UV–Vis, FT-IR, 1D and 2D NMR spectroscopy, and HRMS spectrometry.

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Synthesis of poly(methyl methacrylate)-b-poly(acrylic acid) by DPE method

e-Polymers ◽

10.1515/epoly.2008.8.1.1051 ◽

2008 ◽

Vol 8 (1) ◽

Cited By ~ 2

Author(s):

Dong Chen ◽

Ruixue Liu ◽

Zhifeng Fu ◽

Yan Shi

Keyword(s):

Molecular Weight ◽

Acrylic Acid ◽

Methyl Methacrylate ◽

Diblock Copolymer ◽

Self Assembly ◽

Gel Permeation Chromatography ◽

Amphiphilic Diblock Copolymer ◽

Poly Methyl Methacrylate ◽

Copolymer Poly ◽

Poly Acrylic Acid

AbstractAmphiphilic diblock copolymer poly(methyl methacrylate)-b-poly(acrylic acid) (PMMA-b-PAA) was prepared by 1,1-diphenylethene (DPE) method. Firstly, free radical polymerization of methyl methacrylate was carried out with AIBN as initiator in the presence of DPE, giving a DPE-containing PMMA precursor with controlled molecular weight. tert-Butyl acrylate (tBA) was then polymerized in the presence of the PMMA precursor, and PMMA-b-PtBA diblock copolymer with controlled molecular weight was prepared. Finally, amphiphilic diblock copolymer PMMA-b-PAA was obtained by hydrolysis of PMMA-b-PtBA. The formation of PMMA-b-PAA was confirmed by 1H NMR spectrum and gel permeation chromatography. Transmission electron microscopy and dynamic light scattering were used to detect the self-assembly behavior of the amphiphilic diblock polymers in methanol.

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