Health-related quality of life in patients with moderate-severe psoriasis: Preliminary results on the role of psychopathology and coping strategies in a cohort of patients

2016 ◽  
Vol 33 (S1) ◽  
pp. S384-S384
Author(s):  
M. Fabrazzo ◽  
V. De Santis ◽  
R.V. Puca ◽  
F. Romano ◽  
M. Arrigo ◽  
...  

Psoriasis is a multisystem inflammatory disease associated to several comorbidities with a significant impact on interpersonal and social life. Depression, anxiety symptoms and suicidal ideation–due to psychological distress–are frequently reported. The aim of the study was to assess whether psychological factors–psychopathology, perceived health status and coping strategies–together with clinical and sociodemographic factors, were independent predictors of Quality of Life (QoL) in adult psoriatic patients on topical and/or systemic pharmacological therapy. A cohort of 87 patients (53 M and 34 F), whose mean age was 46 ± 22 years, was analyzed. Coping responses were assessed by COPE and general psychopathology by Self-Reported-Symptom Inventory Revised (SCL-90), while HAM-D and HAM-A evaluated depressive and anxiety symptoms. In addition, perceived health status and QoL were analyzed by Short-Form-36 (SF-36) while the disease's burden assessed by PSODISK. Univariate analyses were performed for each variable to explore the relationship with QoL. Preliminary results indicated that, although not severe, anxiety and depressive symptoms were the most reported among patients along with somatization and obsessive-compulsivity. Female patients used more frequently mental disengagement, focus on and venting of emotions, use of instrumental social support and religious coping. Physical pain and mental health, instead, greatly affected QoL of subjects in a negative manner. PSODISK data analysis showed that general health, itching, serenity, shame and degree of extension of the disease on the skin were the most compromised areas. Moreover, correlation analysis indicated that a worse perception of patients’ health status was associated to poor QoL.Disclosure of interestThe authors have not supplied their declaration of competing interest.

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
A. Barnadas ◽  
◽  
M. Muñoz ◽  
M. Margelí ◽  
J. I. Chacón ◽  
...  

Abstract Background Bone metastasis (BM) is the most common site of disease in metastatic breast cancer (MBC) patients. BM impacts health-related quality of life (HRQoL). We tested prospectively the psychometric properties of the Bone Metastasis Quality of Life (BOMET-QoL-10) measure on MBC patients with BM. Methods Patients completed the BOMET-QoL-10 questionnaire, the Visual Analogue Scale (VAS) for pain, and a self-perceived health status item at baseline and at follow-up visits. We performed psychometric tests and calculated the effect size of specific BM treatment on patients´ HRQoL. Results Almost 70% of the 172 patients reported symptoms, 23.3% experienced irruptive pain, and over half were receiving chemotherapy. BOMET-QoL-10 proved to be a quick assessment tool performing well in readability and completion time (about 10 min) with 0–1.2% of missing/invalid data. Although BOMET-QoL-10 scores remained fairly stable during study visits, differences were observed for patient subgroups (e.g., with or without skeletal-related events or adverse effects). Scores were significantly correlated with physician-reported patient status, patient-reported pain, symptoms, and perceived health status. BOMET-QoL-10 scores also varied prospectively according to changes in pain intensity. Conclusions BOMET-QoL-10 performed well as a brief, easy-to-administer, useful, and sensitive HRQoL measure for potential use for clinical practice with MBC patients. Trial registration NCT03847220. Retrospectively registered on clinicaltrials.gov (February the 20th 2019).


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Silvia Schiavolin ◽  
Rui Quintas ◽  
Marco Pagani ◽  
Stefano Brock ◽  
Francesco Acerbi ◽  
...  

Background. The aim of this paper is to present the preliminary results of QoL, well-being, disability, and coping strategies of patients before neurosurgical procedure.Methods. We analysed data on preoperative quality of life (EUROHIS-QoL), disability (WHODAS-II), well-being (PGWB-S), coping strategies (Brief COPE), and functional status (KPS score) of a sample of patients with brain tumours and cerebrovascular and spinal degenerative disease admitted to Neurological Institute Carlo Besta. Statistical analysis was performed to illustrate the distribution of sociodemographic and clinical data, to compare mean test scores to the respective normative samples, and to investigate the differences between diagnoses, the correlation between tests, and the predictive power of sociodemographic and clinical variables of QoL.Results. 198 patients were included in the study. PGWB-S and EUROHIS-QoL scores were significantly lower than normative population. Patients with spinal diseases reported higher scores in WHODAS-II compared with oncological and cerebrovascular groups. Finally sociodemographic and clinical variables were significant predictors of EUROHIS-QoL, in particular PGWB-S and WHODAS-II.Conclusion. Our preliminary results show that preoperatory period is critical and the evaluation of coping strategies, quality of life, disability, and well-being is useful to plan tailored intervention and for a better management of each patient.


2021 ◽  
Author(s):  
Elaine Valias Sodré Pereira ◽  
Carolina Pessoni Garcia ◽  
Maria José D’Elboux

INTRODUCTION: Assessing quality of life in older adults is relevant due to the significant increase in this population. Based on Maslow’s need hierarchy model, CASP-19 is a broad measure of quality of life that focuses on positive aspects of older adults’ lives, regardless of health conditions or other factors. OBJECTIVE: To compare sociodemographic and health variables with quality of life according to CASP-19 scores. METHODOLOGY: Using data from the Frailty in Brazilian Older People (FIBRA 80+) follow-up study, this study included 233 adults aged ≥ 80 years who resided near the University of Campinas (Campinas, SP, Brazil). Sociodemographic variables (gender, age, and perceived social support), health variables (perceived health status and depressive symptoms) and quality of life were evaluated. RESULTS: The participants were predominantly women (69.09%) with a mean age of 83.46 ± 3.7 years. A total of 77.25% rated their health as fair or good, and 79% showed no signs of depression. The mean CASP-19 score was 41.8 ± 2.62 points, which corresponds to better well-being (total scores range from 0 to 57). Among the instrument’s domains, autonomy and pleasure obtained the highest mean scores (11.15 and 11.64 respectively). When comparing these variables with quality of life, social support (p = 0.001), depressive symptoms (p <0.001), and perceived health status (p <0.001) were statistically significant. CONCLUSIONS: Older adults who were satisfied with their social support, presented no depressive symptoms, and who rated their health as good or very good had higher overall quality of life scores.


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