Hospital admissions and direct costs: A comparative study between paliperidone palmitate and oral antipsychotics

2016 ◽  
Vol 33 (S1) ◽  
pp. s229-s229
Author(s):  
A. Soler Iborte ◽  
S. Galiano Rus ◽  
J.A. Ruíz Sánchez
Keyword(s):  
Hospital Stay ◽  
Hospital Admissions ◽  
Average Length ◽  
Direct Costs ◽  
Average Hospital Stay ◽  
Average Hospital ◽  
Number Of Patients ◽  
Icd 10 ◽  
Schizophrenic Patients ◽  
Competing Interest

IntroductionThe total costs of schizophrenia increased to 2576 million Euros in 2013 in Spain, or 2.7% of the annual cost of health services. The hospitalizations, along with other intermediate resources, such as Day Hospital, etc., significantly contribute to the increase of economic burden. In Spain, the average hospital stay of schizophrenic patients is 18.24 days, totalling to an average cost of 6,753 Euros/patient (370.23 Euros/patient/day).Material and methodsThe sample selected included patients from both sexes, aged between 18 and 65 years old, with diagnostic criteria of schizophrenia (according to DSM-IV and ICD-10), admitted in the Mental Health Hospital Unit (MHHU), Úbeda between 2012 and 2013, with registered visits of at least 2 outpatient visits or 1 hospitalization related to the schizophrenia diagnosis (n = 48).ResultsAfter the start of treatment with the injectable antipsychotic drug of prolonged duration, the number of patients that required hospitalization for any psychiatric motive went from 24 patients (49.7%) to 11 patients (22.4%; P < 0.001). The patients who started treatment with PAP during hospitalization had an average stay of 15.7 days, as compared to 18.24 days of average hospital stay due to schizophrenia in Spain. The direct costs of hospitalization stays due to psychiatric reasons decreased from 162,071.88 Euros to 74,282.95 Euros (P < 0.001).ConclusionsThis observational study shows us that the treatment with PAP reduced the average length of the hospital stay, and resulted in a decreased percentage of re-admissions as compared to oral treatments for schizophrenia. These data led to savings of more than 50% of the direct costs of hospitalization.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Effective doses of paliperidone palmitate (PAP): Retrospective analysis from three years of treatment

2016 ◽  
Vol 33 (S1) ◽  
pp. S540-S540
Author(s):  
S. Galiano Rus ◽  
A. Soler Iborte ◽  
C. Quesada González
Keyword(s):  
Mental Health ◽  
Clinical Practice ◽  
Hospital Admissions ◽  
Average Length ◽  
Average Hospital ◽  
Icd 10 ◽  
Effective Doses ◽  
Technical Specifications ◽  
Competing Interest ◽  
Long Acting

IntroductionThe use of PAP is already much extended in general. The recommended doses in the technical specifications of the drugs, as the result of trial studies, differ from the doses administered in habitual clinical practice. Therefore, the justification of this study is to monitor the average doses prescribed, to be able to reach an agreement on the best doses. To retrospectively analyze the first 32 patients in our area of healthcare, who were prescribed PAP, the doses used at the start of treatment and after 3 years.Materials and methodsTwo initial doses of PAP were analyzed, maximum and current (outpatient) in 32 patients attended in the area of mental health of North Jaen, who started the treatment with PAP between 2012 and 2013, with an average length of time of 2.55 years (SD 2.02). We evaluated the diagnosis (schizophrenia and related disorders, ICD-10 F20), the number of hospital admissions previous and posterior to the start of the treatment and change in weight.ResultsAverage doses: initial: 110.15 mg (SD 32.83), maximum: 165.51 mg (SD 29.76) and maintenance: 146.81 mg (SD 29.59). Average hospital admissions: prior and posterior to the start of treatment: 1.5 and 0.83. An average reduction of 44.06% in admissions was observed.ConclusionsThe data obtained suggests that a dose of 75–200 mg could be effective in the maintenance of patients with schizophrenia and for decreasing the number of new hospital admissions. Fifty percent of the cases can be compensated with long acting peliperidone as a monotherapy.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Hypomethylating agents as first-line therapy in acute myeloid leukemia (AML).

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 7084-7084
Author(s):  
Samuel D Bailey ◽  
Zartash Gul ◽  
Stacey A. Slone ◽  
Emily Marie Van Meter ◽  
Amber Lawson ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Hospital Admissions ◽  
Average Length ◽  
Length Of Hospital Stay ◽  
Median Number ◽  
Cancer Center ◽  
Hypomethylating Agents ◽  
Average Hospital Stay ◽  
Average Hospital ◽  
First Line Therapy

7084 Background: Hypomethylating agents are used in older AML patients (pts) who are not considered candidates for standard induction therapy. However, data regarding their efficacy remains unclear. Methods: We retrospectively evaluated a cohort of 24 consecutive AML pts who were placed on hypomethylation therapy at diagnosis between October 2010 and June 2012 at Markey Cancer Center. Results: Baseline characteristics of the patients are described in table 1. Response rate (CR+PR) was 45.8%. Median number of infections were 1 (8 pts), 2 (5 pts), 3 (4 pts).Median hospital admissions required were 1 (10 pts), 2 (4 pts), 3 (5 pts), 4 or greater (2 pts). Average length of hospital stay was 10.3 days (0-37 days). Median units of packed red cell and platelet transfusions were 10 and 11 units (Range=0-64 and 0-78) respectively. After a median follow up of 145.5 days, 13 pts had died. Cause of death was AML (6 pts), infection and end organ failure (7pts).Median overall survival (OS) was 9.7 months (95%CI: 3.2-16.5 months). On multivariate analysis, blast count less than 30% was borderline significantly associated with better OS (P=0.05). However after addition of average hospital stay in the model only age (HR=1.3, CI=1.06- 1.67), gender (HR=11.5, CI=1.2, 110.5), and average hospital stay were significantly associated with OS (HR=1.2, CI = 1.04- 1.32). Conclusions: In this cohort of pts the median OS was 9.7 months. Older pts and those with longer average hospital stay had a higher mortality. Better selection of pts in a larger cohort who are likely to gain more benefit from these agents may impact outcomes. [Table: see text]

ANÁLISE DESCRITIVA DAS INTERNAÇÕES POR ASMA DE PACIENTES PEDIÁTRICOS NO ESTADO DO TOCANTINS DE 2016 A 2021.

2021 ◽  
Vol 8 (3) ◽  
pp. 94-99
Author(s):  
Gabriela Costa Jácome ◽  
Luca Bontempo ◽  
Evandro Leite Bitencourt ◽  
Andrea Silva do Amaral
Keyword(s):  
Hospital Admission ◽  
Hospital Stay ◽  
Pediatric Patients ◽  
Hospital Admissions ◽  
Transition Period ◽  
Admission Rate ◽  
The State ◽  
Average Hospital Stay ◽  
Old Patients ◽  
Average Hospital

OBJETIVO: A asma é uma doença crônica que possui alta incidência na população infantil e suas exacerbações estão associadas ao aumento nas taxas de internação, piora da qualidade de vida e aumento dos custos. Dessa forma, o objetivo do estudo é descrever o perfil epidemiológico das internações por asma em pacientes pediátricos, no estado do Tocantins, de janeiro de 2016 a maio de 2021. MÉTODO: Consiste em estudo epidemiológico transversal, retrospectivo temporal, descritivo das internações por asma em pacientes pediátricos por meio de coleta de dados disponíveis no Departamento de Informação e Informática do SUS (DATASUS) e Instituto Brasileiro de Geografia e Estatística (IBGE). Verificou-se a incidência das internações segundo mês e ano do atendimento, faixa etária (0-4, 5-9 e 10-14 anos), sexo, média de permanência das hospitalizações e valores médio e total do custo das internações. RESULTADOS: Foi verificado um total de 1.150 internações em menores de 14 anos, correspondendo a 64,83% das hospitalizações por asma no estado. A maior e menor taxa de internação foram em 2017 (69,60 internações/100.000 habitantes) e 2020 (28,39 internações/100.000 habitantes). A maior parte ocorreu em pacientes com até 4 anos (62,87%) e do sexo masculino (61,30%). 60,76% das internações foram no período de chuvas. A média de permanência hospitalar foi de 2,8 dias e valor total gastos foi de R$585.192,71, sendo R$508,43 por internação. CONCLUSÃO: A incidência das internações por asma foi maior em meninos e em lactentes e pré-escolares, grupos que apresentaram maior tempo de permanência hospitalar. Ademais, as internações foram mais frequentes nos meses chuvosos e na transição para a seca. A diminuição observada nos anos de 2020 e 2021 pode ter relação com a pandemia pelo COVID-19, contudo, são necessários mais estudos para o melhor entendimento dessa associação.  Palavras-chave: Asma; Hospitalização; Criança Hospitalizada; Epidemiologia descritiva.  ABSTRACT OBJECTIVES: Asthma is a chronic disease that has a high incidence in the child population and its exacerbation is associated with hospital admission rates growth, life quality worsening and cost increase. Thus, the objective of this paper is to describe the epidemiological profile of asthma related hospital admission in pediatric patients, located in the state of Tocantins, from january 2016 through may 2021. METHOD: It consists in a transversal epidemiological study, temporal retrospective and descriptive of the hospital admissions caused by asthma in pediatric patients through a data collection, having the Department of Information and Informatics of SUS (DATASUS) and the Brazilian Institute of Geography and Statistics (IBGE) as the sources. We verified the rate of admissions by month and year, age group (0-4, 5-9 and 10-14 years old), sex, average hospital stay and average and total of cost admissions. RESULTS: A total of 1.150 admissions were checked in the under 14 years old group, corresponding to 64,83% of admissions by asthma in the state. The highest and lowest rate of admissions were in 2017 (69,60 admissions/100.000 inhabitants) and 2020 (28,39% admissions/100.00 inhabitants). Most of it happened to 4 years old patients or younger (62,87%) and males (61,30%). 60,76% of admissions took place in the rainy season. The average hospital stay was 2,8 days and the total cost was R$585.192,71, each stay costing R$508,43. CONCLUSION: The admission rate by asthma was higher for boys and infants and pre-school children, and these groups that were in the hospital for a longer period of time. Besides, the admissions were frequent during the rainy months and in the transition period between rainy and dryer seasons. The decrease in admissions rate noticed in 2020 and 2021 might be related to the COVID-19 pandemic, even though more research is necessary to understand this correlation. Key-words: Asthma; Hospitalization; Child, Hospitalized; Epidemiology, Descriptive.

scholarly journals RELATIONSHIP BETWEEN ICU WAITING AND MORTALITY RATE IN PATIENTS UNDER MECHANICAL VENTILATION ADMITTED IN EMERGENCY ROOM

2020 ◽  
Author(s):  
Layanna Alves da Silva Andrade ◽  
Monica Lucia Soares Borges ◽  
Geovane Rossone Reis ◽  
Aktor Hugo Teixeira ◽  
Rebeca Oliveira Crispim da Silva ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Mortality Rate ◽  
Hospital Stay ◽  
Average Length ◽  
Total Mortality ◽  
Length Of Hospital Stay ◽  
Field Research ◽  
Average Hospital ◽  
Number Of Patients ◽  
Using Data

Background: The number of patients who remain on prolonged mechanical ventilatory assistance has recently increased. The average length of hospital stay intervenes directly with the number of beds essential for assistance to a given population and is weighted as an indicator of service efficiency. Objective: To investigate the average time in which patients on mechanical ventilation admitted to the emergency department of a hospital remain waiting for a place in the ICU. Materials and Methods: Quantitative field research, where data collection was performed using data from medical records, admission books, death books / outcome of hospitalized patients and in line with pre-established criteria under mechanical ventilation. Mechanical ventilation patients admitted to the ER and the ICU, over 18 years old, were recruited. Results: The research comprises a sample of 67 patients. The average hospital stay was 334 hours and 36 minutes. The general ratio was for every 03 patients who entered for treatment, 01 was discharged and 02 died. The total mortality rate of the sample was 68.65%. Conclusion: The length of stay in ER and ICU in patients on mechanical ventilation is related to the high mortality rate.

A case of rare allele T 126, 30,32 base pairs in a schizophrenic patient: A study case

2016 ◽  
Vol 33 (S1) ◽  
pp. S585-S586
Author(s):  
A.I. Sabau ◽  
P. Cristina ◽  
B. Valerica ◽  
P. Delia Marina
Keyword(s):  
Schizophrenic Patient ◽  
Complex Disease ◽  
Susceptibility Gene ◽  
Rflp Analysis ◽  
Rare Allele ◽  
Base Pairs ◽  
Gene Coding ◽  
Icd 10 ◽  
Schizophrenic Patients ◽  
Competing Interest

IntroductionSchizophrenia is a severe and complex disease clinically characterized by disturbed thought processes, delusions, hallucinations and reduced social skills. Gene coding for neregulin 1 (NRG 1) located in 8 p21chromosomeand single nucleotide polymorphism (SNPs) have been identified strongly supporting NRG1 gene as a susceptibility gene for schizophrenia.ObjectiveThe present preliminary study, determines the relationship between polymorphism nucleotide sites (SNPs2) of NRG1 gene and schizophrenia.AimsIdentifying rare allele T of neregulin 1 genein schizophrenic patients.MethodWe analyzed the polymorphism (SNPs2) of NRG1 gene in 20 patients recruited from Psychiatry Department of Emergency Clinical Hospital of Arad diagnosed with schizophrenia according to DSM-5-TM and ICD-10 criteria and 10 healthy controls. From all subjects, we obtained 2 mL of peripheral blood samples. Genomic DNA was extracted using the phenol-chloroform method. Genotyping was performed byPCR-based RFLP analysis for all subjects. The obtained PCR product mixture was completely digested with restriction enzyme, separated on SNP1 and SNP2 agarose gel. We present the case of a 31 years old, male, schizophrenic patient with the SNPs2 polymorphism and rare allele T 126.ResultsIn both groups, common allele G 127 and 60 base pairs was identified but only 2 schizophrenic patients presented rare allele T 126 and 30,32 base pairs.ConclusionsThe polymorphism SNPs2 of NRG1 gene with rare allele T 126 and 30,32 base pairs, may play a role in predisposing an individual to schizophrenia. Further and extended replicating studies with multiple sequencing of NRG1 gene are necessary.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Unimed Recife's experience in treating 1,039 patients with Covid-19

2021 ◽  
Author(s):  
Marcelo Moraes Valença ◽  
Martha Maria Romeiro Figueiroa F. Fonseca ◽  
Cátia Arcuri Branco ◽  
Alex Maurício Garcia Santos ◽  
Antonio Oliveira ◽  
...  
Keyword(s):  
Health Management ◽  
Demographic Data ◽  
The Elderly ◽  
Obese Patients ◽  
Mechanical Ventilator ◽  
Average Hospital Stay ◽  
Average Hospital ◽  
Management Platform ◽  
Pathophysiological Process ◽  
Number Of Patients

ObjectiveTo describe the features related to patients with Covid-19 admitted to Unimed Recife hospitals, Recife, Brazil, evaluating demographic data, lethality, use of a mechanical ventilator, presence of associated diseases, the need to use the ICU, among other aspects related to the prognosis of these patients.MethodData were collected from the DRG Brazil health management platform, including the period from March 16, 2020, when the first patient with Covid-19 was admitted to the Hospital da Unimed III, until January 31, 2021. All patients admitted to one of the three hospitals of Unimed Recife - Hospital Unimed Recife I, Hospital Unimed Recife III, and Hospital Geral Unimed Recife – were included in the study. In the same period, we evaluated the number of patients with Covid-19 or suspected Covid-19 who were seen in the emergency room at Hospital Unimed Recife III.ResultsOne hundred twenty-six thousand five hundred fifty-three patients were seen in the Emergency Unit of Hospital Unimed Recife III in the period between March 26, 2020, and January 31, 2021; of those 126,553 patients seen in the emergency 39,340 (31.09%) patients were diagnosed with having Covid-19 or suspected of Covid-19. In the 10-month period, 1,039 patients with Covid-19 were hospitalized, 61% with hypertension, 31.1% with SARS, 30.0% with diabetes, and 9.9% were obese. The average hospital stay was 11.2 days. 342/1,039 (32.9%) patients were admitted to the ICU, and 57.9% of them had mechanical ventilation. The overall lethality was 13.76% (143 deaths/1,039 inpatients). An increase in lethality by Covid-19 was associated with increased age. Lethality in the first period of the Covid-19 pandemic was significantly higher when compared to the last 5 months of the pandemic(17.6% versus 9.7%). Obesity significantly increased lethality in patients with Covid-19 [120 deaths/1,016 non-obese patients (11.8%) versus 23 deaths/103 obese patients (22.3%), OR 2.15 (1.30 - 3.50), p = 0.005)].ConclusionWe conclude that Covid-19 is a disease with a poor prognosis, especially in the elderly and obese patients. In the second 5-month period of the Covid-19 pandemic, we noticed a significant reduction in lethality by Covid-19 in hospitalized patients. Covid-19 is a new disease and the mechanism by which the viruses multiply or how the pathophysiological process occurs in the infected organism are still barely understood.

scholarly journals Insuficiência renal aguda no Nordeste brasileiro: morbimortalidade e custos públicos

2019 ◽  
Vol 13 ◽  
Author(s):  
Edison Vitório de Souza Júnior ◽  
Diego Pires Cruz ◽  
Gabriel Aguiar Nunes ◽  
Giovanna Maria Nascimento Caricchio ◽  
Sávio Luiz Ferreira Moreira ◽  
...  
Keyword(s):  
Hospital Stay ◽  
Kidney Diseases ◽  
Northeastern Brazil ◽  
Average Hospital Stay ◽  
Average Hospital ◽  
Average Value ◽  
Hospital Morbidity ◽  
Public Costs ◽  
Care Costs ◽  
Sistemas De Informacion

Objetivo: descrever a morbimortalidade hospitalar e custos públicos relacionados à insuficiência renal aguda no Nordeste brasileiro. Método: trata-se de estudo quantitativo, ecológico e descritivo realizado com dados do Sistema de Informações Hospitalares. Coletaram-se as variáveis: internações; óbitos; mortalidade; valores dos serviços hospitalares; valores médios gastos com as internações e média de permanência hospitalar. Analisaram-se os dados com estatística descritiva, apresentando-os em tabelas elaboradas pelo software Excel. Resultados: registraram-se 21.100 internações, 4.460 óbitos e mortalidade de 21,1%. Destacaram-se a Bahia nas internações (28,6%) e óbitos (28,7%) e Sergipe na letalidade (35,6%). Gerou-se custo público superior a R$ 37,6 milhões e a Bahia responsabilizou-se por 32,1%. Revelou-se valor médio de R$ 1.969,97 para cada internação e a média de permanência hospitalar foi de 10,2 dias. Conclusão: conclui-se que as variáveis epidemiológicas apresentaram maior prevalência nos Estados da Bahia e Sergipe. Evidenciou-se, além disso, comportamento crescente das internações, implicando o incremento dos custos públicos. Descritores: Saúde Pública; Nefrologia; Nefropatias; Epidemiologia; Custos de Cuidados de Saúde; Sistemas de Informação. Abstract Objective: to describe hospital morbidity and mortality and public costs related to acute renal failure in northeastern Brazil. Method: this is a quantitative, ecological and descriptive study conducted with data from the Hospital Information System. The following variables were collected: hospitalizations; deaths; mortality; values of hospital services; average values spent on hospitalizations and average hospital stay. Data was analyzed with descriptive statistics and presented in tables prepared by Excel software. Results: 21,100 hospitalizations, 4,460 deaths and 21.1% mortality were registered. Bahia stood out in hospitalizations (28.6%) and deaths (28.7%) and Sergipe in lethality (35.6%). It generated a public cost over R $ 37.6 million and Bahia accounted for 32.1%. An average value of R $ 1,969.97 was revealed for each hospitalization and the average hospital stay was 10.2 days. Conclusion: it is concluded that the epidemiological variables were more prevalent in the states of Bahia and Sergipe. In addition, the increasing behavior of hospitalizations was evidenced, implying an increase in public costs. Descriptors:  Public Health; Nephrology; Kidney Diseases; Epidemiology; Health Care Costs; Information Systems.Resumen Objetivo: describir la morbimortalidad hospitalaria y los costos públicos relacionados con la Insuficiencia Renal Aguda en el Noreste de Brasil. Método: se trata de un estudio cuantitativo, ecológico y descriptivo realizado con datos del Sistema de Informaciones Hospitalarias. Se recogieron las siguientes variables: hospitalizaciones; muertes, mortalidad, valores de los servicios hospitalarios; promedio de valores gastados en admisiones y promedio de permanencia hospitalaria. Los datos se analizaron con estadísticas descriptivas y se presentaron en tablas elaboradas por el software Excel. Resultados: se registraron 21.100 admisiones, 4.460 muertes y 21.1% de mortalidad. Bahía se destacó en hospitalizaciones (28.6%) y muertes (28.7%), y Sergipe en letalidad (35.6%). Se generó un costo público de más de R$ 37,6 millones y Bahía fue responsable del 32.1%. El valor medio de R $ 1,969.97 se reveló para cada hospitalización y la permanencia hospitalaria con promedio de 10,2 días. Conclusión: se concluye que las variables epidemiológicas presentaron mayor prevalencia en los Estados de Bahía y Sergipe. Además, hubo evidencia de un mayor comportamiento de hospitalización, lo que implica un aumento en los costos públicos. Descriptores: Salud Pública; Nefrología; Enfermedades Renales; Epidemiología; Costos de la Atención en Salud; Sistemas de Información.

REDUCING THE LITERAL AND HUMAN COST OF CHILD ABUSE: IMPACT OF A NEW HOSPITAL MANAGEMENT SYSTEM

PEDIATRICS ◽  
1973 ◽  
Vol 51 (5) ◽  
pp. 840-848
Author(s):  
Eli H. Newberger ◽  
John J. Hagenbuch ◽  
Nancy B. Ebeling ◽  
Elizabeth Pivchik Colligan ◽  
Jane S. Sheehan ◽  
...  
Keyword(s):  
Child Abuse ◽  
Hospital Stay ◽  
Hospital Cost ◽  
Hospital Costs ◽  
Average Hospital Stay ◽  
Total Hospital ◽  
Average Hospital ◽  
Consultation Group ◽  
Human Cost ◽  
Hospital Management System

Social service personnel from one public and two voluntary agencies were integrated into a consultation group in an academic pediatric hospital, leading to a reduction in the actual cost of medical services and the risk of reinjury subsequent to the diagnosis of child abuse. In the 1969-1970 hospital year, 62 cases of child abuse were seen, of which 39 were hospitalized. The average hospital stay was 29 days; the average hospital cost $3,000. Total hospital costs for the 39 cases were $123,000, of which bed costs made up $95,000. There were at least three subsequent incidents of child abuse in these 39 cases, and there was one subsequent death; the reinjury rate was 10% for hospitalized cases. In September 1970 the Trauma X Group, an interdisciplinary, interagency consultation unit based in the hospital, was formed. With formal consultation and continued surveillance after discharge by the Trauma X Group, the following data were obtained from the 1970-1971 hospital year. Of 86 cases, 60 were hospitalized. The average hospital stay was 17 days; the average hospital cost $2,500. Total hospital costs for the 60 cases was $150,000, of which bed costs made up $101,000. There was one incident of reinjury and no deaths subsequent to diagnosis in these 60 cases; the reinjury rate was 1.7%. The risk of reinjury calculated from a modified life table was reduced from 8% in the year previous to the formation of the group to 7% and 2%, respectively, in the subsequent year and six-month periods, supporting the dollar-cost impression of effectiveness. Foster placement, furthermore, was infrequent and does not explain the differential impact of the Trauma X Group in the intervals under study.

Paliperidone Palmitate Study in Patients With Personality Disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S505-S505
Author(s):  
M.A. Gutierrez Ortega ◽  
D.P. María Dolores ◽  
M.A. Manuel ◽  
M.M. Esther
Keyword(s):  
Personality Disorder ◽  
Personality Disorders ◽  
Hospital Admissions ◽  
Average Length ◽  
Paliperidone Palmitate ◽  
Emergency Visits ◽  
Actual Clinical Practice ◽  
Average Length Of Stay ◽  
Psychopharmacological Treatment ◽  
Competing Interest

IntroductionPersonality disorders are chronic affectation of mood, impulsivity, aggression and anxiety. It is thought to have biological factors related to the development of personality disorders.AimsTo evaluate and compare the efficacy of injectable paliperidone in actual clinical practice of patients diagnosed with Personality Disorder, compared to other treatments.MethodsWe conducted a descriptive, restrospective and observational study from January 2012 to June 2015 including all the patients who are treated with paliperidone palmitate extended-release injectable suspension with a diagnosis of Personality Disorder according to DSM 5. We included patients with at least 12 months of treatment and the results were compared with respect to the 12 months prior to taking said drug. Variables studied: medical diagnosis, hospital admissions, average length of stay, total number of emergency visits or other devices, maintenance doses.ResultsWe recruited 14 patients (7 women and 7 men) with a mean age of 36.2. 64.29% of patients had borderline personality disorder; 21.43% unspecified personality disorder. The mean dose of maintenance treatment is 105.357. Before the treatment, the quantity of total number of hospital admission are 1.14 versus 0.429 after treatment. The number of stay is also decreased from 13.7 to 3.5; like emergency room visits or to other devices. 78.57% of patients continue to psychopharmacological treatment. Fifty percent of patients undergoing treatment with another antipsychotic (P < 0.05).ConclusionsThe present results show that paliperidone palmitate can be an effective way to control the most characteristic symptoms of Personality Disorders, and reducing emergency visits, hospitalisations and other devices.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Circumcision With Plastic Clamb in Newborn Infants

2019 ◽  
Vol 1 (2) ◽  
pp. 49-55
Author(s):  
Yusuf Atakan Baltrak
Keyword(s):  
Average Length ◽  
Newborn Infants ◽  
Late Period ◽  
Average Hospital Stay ◽  
Surgical Operation ◽  
Average Hospital ◽  
Study Results ◽  
Operative Complications ◽  
Physical Examinations ◽  
Hospital Stay Duration

Various devices were used to carry circumcision operation out. It noted that these devices, especially the Plastic Clamp method, significantly decrease complications as long as basic surgical rules, are followed. This study aims to examine the application of Plastic Clamp circumcision in infants. Children whose physical examinations revealed circumcision contradictions excluded from the study. During the study period, a total of 485 children was circumcised using the plastic clamp method under sedated anesthesia and by a single pediatric surgeon. Measurements take before operations and plastic clamps with diameters ranging from 1.2 to 1.6 cm used. The duration of the surgical procedure, early and late period post-operative complications, the separation duration of the plastic clamp, and problems evaluated. Study Results, the average length of the surgical operation was determined to be 5.5 minutes. The average hospital stay duration of the patients was 2 hours. During the follow-ups, edemas were observed in mucosal areas of 24 (4.9%) patients, 48 hours after the clamp placed and edema and swelling recovered seven days after the circumcision at the latest. On average, it observed that plastic clamp separated on its own in 7.1 days. It noted that in 4 (0.8%) patients, the plastic clamp separated prematurely during 6 hours following the operation due to pulling. Conclusion study plastic Clamp (Alisklamp) is starting to gain popularity because it falls off on its own and that it can be applied quickly under local anesthesia

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