Hope for predicting successful pregnancy in couples with recurrent losses?

The relationship between the intestinal and vaginal dysbiosis was explained. The necessity of correction of disbiotical changes with usage oral probiotics, in particular Laktovit Forte was demonstrated. The terms of prophylactical administration Laktovit Forte during pregnancy were described. Key words: microbiocenosis of the intestine and the vagina, bacterial vaginosis, pregnancy, probiotics, Laktovit Forte.

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Incidence of successful pregnancy after weight loss interventions in infertile women: a systematic review and meta-analysis of the literature

10.26226/morressier.573c1513d462b80296c988c4 ◽

2016 ◽

Author(s):

Loredana Maria Sosa Fernandez

Keyword(s):

Systematic Review ◽

Weight Loss ◽

Meta Analysis ◽

Successful Pregnancy ◽

Infertile Women ◽

Weight Loss Interventions

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Successful pregnancy after 21-nodule removal by abdominal myometrectomy

Perinatologia ◽

10.26416/peri.1.2.2017.836 ◽

2017 ◽

Vol 2 (1) ◽

pp. 89

Author(s):

Răzvan Ciortea ◽

Andrei Mihai Malutan ◽

Marina Dudea ◽

Carmen Elena Bucuri ◽

Maria Rada ◽

...

Keyword(s):

Successful Pregnancy

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Treatment of Repeated Implantation Failures with Sequential Embryo Transfer to Achieve a Successful Pregnancy: A Case Report

Archives of Clinical and Biomedical Research ◽

10.26502/acbr.50170130 ◽

2020 ◽

Vol 04 (06) ◽

Author(s):

Lingjin Xia, ◽

Qi Che ◽

Miao Liu ◽

Xinmei Lu ◽

Xiang Cao ◽

...

Keyword(s):

Case Report ◽

Embryo Transfer ◽

Successful Pregnancy

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Faculty Opinions recommendation of Activating KIR2DS4 is expressed by uterine NK cells and contributes to successful pregnancy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726930261.793534611 ◽

2017 ◽

Author(s):

Philippe Le Bouteiller

Keyword(s):

Nk Cells ◽

Successful Pregnancy ◽

Uterine Nk Cells

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Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review

BMC Endocrine Disorders ◽

10.1186/s12902-020-00677-3 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yi Zhang ◽

Cheng Chen ◽

Min Lin ◽

Kan Deng ◽

Huijuan Zhu ◽

...

Keyword(s):

Case Report ◽

Pituitary Adenoma ◽

Literature Review ◽

Pituitary Adenomas ◽

Sella Turcica ◽

Infertile Woman ◽

Mass Treatment ◽

Successful Pregnancy ◽

Case Presentation ◽

Transsphenoidal Resection

Abstract Background Functional gonadotroph adenomas (FGAs) are rare adenomas that most commonly secrete FSH. However, solitary LH-secreting pituitary adenomas are unusual. Case presentation A 30-year-old woman with elevated LH and normal FSH presented with inability to conceive. An MRI revealed an enlarged sella turcica and an intrasellar mass. Treatment with transsphenoidal resection led to normalization of LH and estradiol, as well as successful pregnancy. And we reviewed 6 cases of LH-secreting pituitary adenomas from 1981 to 2020. Conclusions Our case is unique because of the LH-secreting pituitary adenoma without FSH hypersecretion. This case indicates that pituitary adenoma should be considered when other diseases causing infertility have been excluded.

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HMGA1 Is a Potential Driver of Preeclampsia Pathogenesis by Interference with Extravillous Trophoblasts Invasion

Biomolecules ◽

10.3390/biom11060822 ◽

2021 ◽

Vol 11 (6) ◽

pp. 822

Author(s):

Keiichi Matsubara ◽

Yuko Matsubara ◽

Yuka Uchikura ◽

Katsuko Takagi ◽

Akiko Yano ◽

...

Keyword(s):

Protein A ◽

High Mobility ◽

Extravillous Trophoblast ◽

High Mobility Group Protein ◽

Successful Pregnancy ◽

Group Protein ◽

Serious Disease ◽

Proliferation And Invasion ◽

Extravillous Trophoblasts ◽

Fertilized Egg

Preeclampsia (PE) is a serious disease that can be fatal for the mother and fetus. The two-stage theory has been proposed as its cause, with the first stage comprising poor placentation associated with the failure of fertilized egg implantation. Successful implantation and placentation require maternal immunotolerance of the fertilized egg as a semi-allograft and appropriate extravillous trophoblast (EVT) invasion of the decidua and myometrium. The disturbance of EVT invasion during implantation in PE results in impaired spiral artery remodeling. PE is thought to be caused by hypoxia during remodeling failure–derived poor placentation, which results in chronic inflammation. High-mobility group protein A (HMGA) is involved in the growth and invasion of cancer cells and likely in the growth and invasion of trophoblasts. Its mechanism of action is associated with immunotolerance. Thus, HMGA is thought to play a pivotal role in successful pregnancy, and its dysfunction may be related to the pathogenesis of PE. The evaluation of HMGA function and its changes in PE might confirm that it is a reliable biomarker of PE and provide prospects for PE treatment through the induction of EVT proliferation and invasion during the implantation.

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