Antioxidant activity and bioactive components of the aerial parts of Hypericum perforatum L. from Epirus, Greece

2009 ◽  
Vol 117 (3) ◽  
pp. 398-404 ◽  
Author(s):  
Eleni M. Gioti ◽  
Yiannis C. Fiamegos ◽  
Dimitris C. Skalkos ◽  
Constantine D. Stalikas
2012 ◽  
Vol 48 (2) ◽  
pp. 909-915 ◽  
Author(s):  
Francisco J. Sánchez-Muniz ◽  
Raul Olivero-David ◽  
Mehdi Triki ◽  
Lorena Salcedo ◽  
María José González-Muñoz ◽  
...  

2006 ◽  
Vol 60 (3-4) ◽  
pp. 61-71 ◽  
Author(s):  
Sandra Glisic ◽  
Sretko Popadic ◽  
Dejan Skala

St. John's Wort, the Hypericum perforatum L. is one of the most analyzed plant species today. Plant was characterized with a wide ecological spectrum and is a plant with beautiful yellow flowers. St. John's Wort was used and still is in used in traditional medicine all over the World. Many bioactive components from St. John's Wort like hypericine, hyperforine, qercetrine and essential oil, were isolated and have been used in medicine. The most popular use of Hipericum extract is as an antidepressant for the medicinal treatment of mild and high depression. The medical use of hyperforine in photodynamic therapy for cancer treatment has now been intensively analyzed. The extract of St. John's Wort showed high antimicrobial, even on pathogenic microorganisms as well as antiviral activity. The use of bioactive components from St. John's Wort depends on the possibility to isolate them in the pure state. It seems that supercritical extraction with carbon dioxide might to be the best solution for obtaining pure extract as well as some of the components present in the essential oil and extract of St. John's Wort. Such a conclusion is supported by the many results of recently performed and published in scientific journals.


2015 ◽  
Vol 63 (2) ◽  
pp. 152 ◽  
Author(s):  
Dolja Pavlova ◽  
Irina Karadjova ◽  
Ilina Krasteva

The herb Hypericum perforatum L. – otherwise known as St John’s Wort – that grows on serpentine and non-serpentine sites is widely used in traditional medicine in Bulgaria. Plant aerial parts (Hiperici herba) as well as methanol/water (1 : 1) and water extracts prepared from eight populations growing on and off serpentine were analysed for essential (Fe, Mn, Cr, Co, Cu, Zn) and toxic (Ni, Cd, Pb) elemental concentration using inductively plasma optical emission spectrometry and electro thermal atomic absorption spectrometry. The results showed that metal concentrations varied across sites. Non-serpentine populations were well separated based on their total metal concentrations. The plant is Ni tolerant, but has the potential to accumulate trace elements at toxic levels. The transfer of elements from the herb material to an extract was solvent and metal dependent. The highest mobility, e.g. percentages of extraction, was found for Cu, Zn and Ni in all extracts. The amount of Cd, Ni and Cr was above the permissible limits in dry plant material and both types of extracts. The element concentrations found in this medicinal plant show that people should be careful when collecting it from serpentine sites and using it for medication.


2017 ◽  
Vol 14 (8) ◽  
pp. e1700100 ◽  
Author(s):  
Miriam Heinrich ◽  
Peter Lorenz ◽  
Rolf Daniels ◽  
Florian C. Stintzing ◽  
Dietmar R. Kammerer

2006 ◽  
Vol 1 (12) ◽  
pp. 1934578X0600101 ◽  
Author(s):  
Gelsomina Fico ◽  
Sara Vitalini ◽  
Noemi Colombo ◽  
Franca Tomè

Four species of Hypericum growing in Italy were characterized morphologically and chemically: Hypericum perforatum L., H. maculatum Crantz., H. calycinum L. and H. pulchrum L. The composition of secondary metabolites (phloroglucinols, naphthodianthrones, flavonoids) in the aerial parts of plants collected in different habitats was analysed. The four species show different compositions of phloroglucinols and naphthodianthrones, but there was no qualitative difference in flavonoid content of the species analysed. Study of main-constituent variation during the ontogenetic cycle showed that hypericin decreases and hyperforin increases during the reproductive phase. In St. John's Wort, hypericin and hyperforin are thought to be localised in black nodules. Our investigation shows no clear correlation between either the presence or absence of nodules and hypericin or hyperforin content.


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