Structured silica materials as innovative delivery systems for the bacteriocin nisin

2021 ◽  
pp. 130599
Author(s):  
Luis Fernando Wentz Brum ◽  
Cristiane dos Santos ◽  
João Henrique Zimnoch Santos ◽  
Adriano Brandelli
Keyword(s):  
Delivery Systems ◽  
Silica Materials ◽  
Structured Silica

scholarly journals Silica Materials for Medical Applications

2008 ◽  
Vol 2 (1) ◽  
pp. 1-9 ◽  
Author(s):  
María Vallet-Regí ◽  
Francisco Balas
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Chemical Composition ◽  
Drug Delivery Systems ◽  
Drug Carrier ◽  
Delivery Systems ◽  
Medical Applications ◽  
Synthesis Techniques ◽  
Silica Materials ◽  
Bone Repairing

The two main applications of silica-based materials in medicine and biotechnology,i.e.for bone-repairing devices and for drug delivery systems, are presented and discussed. The influence of the structure and chemical composition in the final characteristics and properties of every silica-based material is also shown as a function of the both applications presented. The adequate combination of the synthesis techniques, template systems and additives leads to the development of materials that merge the bioactive behavior with the drug carrier ability. These systems could be excellent candidates as materials for the development of devices for tissue engineering.

Nanostructured Silica Materials As Drug-Delivery Systems for Doxorubicin: Single Molecule and Cellular Studies

Nano Letters ◽  
2009 ◽  
Vol 9 (8) ◽  
pp. 2877-2883 ◽  
Author(s):  
Timo Lebold ◽  
Christophe Jung ◽  
Jens Michaelis ◽  
Christoph Bräuchle
Keyword(s):  
Drug Delivery ◽  
Single Molecule ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Silica Materials ◽  
Nanostructured Silica

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

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