UPLC-ESI-MS/MS based identification and antioxidant, antibacterial, cytotoxic activities of aqueous extracts from storey onion (Allium cepa L. var. proliferum Regel)

2020 ◽  
Vol 130 ◽  
pp. 108969 ◽  
Author(s):  
Yanyan Zhou ◽  
Cong Li ◽  
Bang Feng ◽  
Bang Chen ◽  
Lihua Jin ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Cytotoxic Activities ◽  
Aqueous Extracts ◽  
Esi Ms ◽  
Allium Cepa L

scholarly journals Citogenotoxicidade de extratos aquosos de Erythrina fusca Lour. sobre o ciclo celular de Allium cepa L / Citotoxity and genotoxity of aqueous extracts of Erythrina fusca Lour. about the cell cycle of Allium cepa L

2021 ◽  
Vol 7 (10) ◽  
pp. 99270-99285
Author(s):  
Rosieli Barboza Bispo ◽  
Elisa dos Santos Cardoso ◽  
Nilo Leal Sander ◽  
Joari Costa De Arruda ◽  
Alex Souza Rodrigues ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Allium Cepa ◽  
Aqueous Extracts ◽  
Allium Cepa L ◽  
Ciclo Celular

scholarly journals Antiproliferative action of aqueous extracts of Hymenaea stigonocarpa Mart. (Fabaceae) on the cell cycle of Allium cepa L.

2014 ◽  
Vol 86 (3) ◽  
pp. 1147-1150 ◽  
Author(s):  
LOURRAN P. LACERDA ◽  
GEIZ MALAQUIAS ◽  
ANA PAULA PERON
Keyword(s):  
Cell Cycle ◽  
Allium Cepa ◽  
Test System ◽  
Control Group ◽  
Aqueous Extracts ◽  
Root Cells ◽  
Antiproliferative Action ◽  
Allium Cepa L ◽  
Meristematic Root ◽  
Number Of Cells

In this study we evaluated the action of crude aqueous extracts obtained from rhytidome of Hymenaea stigonocarpa (jatobá-do-cerrado) on Allium cepa meristematic root cells in three concentrations: 0.082, 0.164, 0.328g/mL, at exposure times of 24 and 48 h. The slides were prepared by the crushing technique, and cells analyzed throughout the cell cycle, totaling 5000 for each control group and concentration. It was found that all three concentrations, including the lowest which is considered ideal for use, in all exposure times, had significant antiproliferative action on the cell cycle of this test system. For cells under division, we observed a high number of cells in prophase. Therefore, under the conditions studied H. stigonocarpa indicated to be cytotoxic.

scholarly journals EFEITO CITOTÓXICO DE EXTRATOS AQUOSOS DE ARTEMISIA ABSINTHIUM L. SOBRE O CICLO CELULAR DE ALLIUM CEPA L. / CYTOTOXIC EFFECT OF AQUEOUS EXTRACTS OF ARTEMISIA ABSINTHIUM L. ON THE CELL CYCLE OF ALLIUM CEPA L.

2020 ◽  
Vol 6 (9) ◽  
pp. 64893-64906
Author(s):  
Daniele Paula Maltezo ◽  
Alex Souza Rodrigues ◽  
Uéliton Alves de Oliveira ◽  
Larissa Lemes dos Santos ◽  
Kelli Évelin Müller Zortéa ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Allium Cepa ◽  
Cytotoxic Effect ◽  
Aqueous Extracts ◽  
Artemisia Absinthium ◽  
Allium Cepa L ◽  
Ciclo Celular

scholarly journals Chromatographic analysis, antiproliferative effect and genotoxicity of aqueous extracts of Citrus sinensis (L.) osbeck on the Allium cepa L. test system

2015 ◽  
Vol 31 (4) ◽  
pp. 1213-1221 ◽  
Author(s):  
Marília Tedesco ◽  
Andrielle Wouters Kuhn ◽  
Aline Augusti Boligon ◽  
Haywood Dail Laughinghouse IV ◽  
Margareth Linde Athayde ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Chromatographic Analysis ◽  
Citrus Sinensis ◽  
Test System ◽  
Antiproliferative Effect ◽  
Aqueous Extracts ◽  
Allium Cepa L

scholarly journals Action of Aqueous Extracts of Phyllanthus niruri L. (Euphorbiaceae) leaves on Meristematic Root Cells of Allium cepa L.

2014 ◽  
Vol 86 (3) ◽  
pp. 1131-1137 ◽  
Author(s):  
ERASMOVLANE S.B. NEVES ◽  
PAULO MICHEL PINHEIRO FERREIRA ◽  
LEONARDO H.G.M. LIMA ◽  
ANA PAULA PERON
Keyword(s):  
Cell Cycle ◽  
Allium Cepa ◽  
Root Meristem ◽  
Test System ◽  
Aqueous Extracts ◽  
Phyllanthus Niruri ◽  
Root Cells ◽  
Allium Cepa L ◽  
Chi Squared ◽  
Meristematic Root

This study aimed to evaluate the effects of aqueous extracts of dried Phyllanthus niruri L. (stonebreaker) leaves on Allium cepa L. root meristem cells at four concentrations, 0.02 (usual concentration), 0.04, 0.06 and 0.08mg/mL and exposure times of 24 and 48 hours. For each concentration we used a group of five onion bulbs that were first embedded in distilled water and then transferred to their respective concentrations. The radicles were collected and fixed in acetic acid (3:1) for 24 hours. The slides were prepared by the crushing technique and stained with 2% acetic orcein. Cells were analyzed throughout the cell cycle, totaling 5000 for each control and exposure time. The calculated mitotic indices were subjected to the Chi-squared statistical analysis (p<0.05). From the results obtained it was observed that all four concentrations tested had significant antiproliferative effect on the cell cycle of this test system. We also found the presence of cellular aberrations such as colchicined metaphases, anaphasic and telophasic bridges, and micronuclei in the two exposure times for all concentrations evaluated. Therefore, under the conditions studied the concentrations of aqueous extracts of leaves of P. niruri showed to be cytotoxic and genotoxic.

scholarly journals Evaluation of the cytotoxic and genotoxic effect of Allium cepa L. (Amaryllidaceae) root cells after exposure in water samples of five lakes of Alta Floresta, State of Mato Grosso

2020 ◽  
Vol 15 (1) ◽  
pp. 1 ◽  
Author(s):  
Leila Pereira Neves Ramos ◽  
Douglas Machado Leite ◽  
Weslaine De Almeida Macedo ◽  
Cyntia Beatriz Magalhães Farias ◽  
Ademilso Sampaio de Oliveira ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Water Samples ◽  
Water Volume ◽  
Cytotoxic Activities ◽  
Cytotoxic Potential ◽  
Root Cells ◽  
Mato Grosso ◽  
Allium Cepa L ◽  
Cell Cycle Inhibition ◽  
Positive Controls

  This study evaluated genotoxic and cytotoxic potential of water samples through the analysis of Allium cepa root cells exposed to samples from five urban lakes of Alta Floresta, state of Mato Grosso. The samples were obtained in the dry and rainy periods, October 2014 and April 2015, respectively, at five distinct points. The collection points were as follows: Lake 01, located in MT 206; Lake 02, in Avenida Perimetral Rogério Silva; Lake 03, in Sector C; Lake 04 on Teles Pires Avenue; and Lake 05, in the Cidade Bela District. Bioassays using Allium cepa bulbs were taken from the water at each point, and comparisons were made with the negative and positive controls. The results found the presence of genotoxic and cytotoxic activities on the roots of A. cepa, indicating high potential in cell cycle inhibition. This result may also be caused by the influences of seasonal periods, taking into account that in the rainy season there is a greater transport of cytotoxic substances by rainwater, and in the dry season, a higher concentration of pollutants due to the reduction of water volume, resulting in a greater interaction of the concentrators as well as a greater concentration of the elements found in the water of these lagoons.

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