Response surface methodology based optimization of in situ transesterification of dry algae with methanol, H2SO4 and NaOH

Fuel ◽  
2019 ◽  
Vol 239 ◽  
pp. 511-520 ◽  
Author(s):  
Rahul Chamola ◽  
Mohd. Fazil Khan ◽  
Anna Raj ◽  
Manthan Verma ◽  
Siddharth Jain
Biofuels ◽  
2019 ◽  
pp. 1-7
Author(s):  
Aline Terra Soares ◽  
Emmanuel Bezerra D’Alessandro ◽  
Rafael Garcia Lopes ◽  
Roberto Bianchini Derner ◽  
Nelson Roberto Antoniosi Filho

2012 ◽  
Vol 581-582 ◽  
pp. 819-822 ◽  
Author(s):  
Bin Meng ◽  
Jin Hui Peng

The corundum-mullite was toughened by in-situ synthesized mullite whiskers and the process parameters influencing the fracture toughness of corundum-mullite, such as sintering temperature, addition amount of AlF3 and V2O5, were optimized by means of response surface method. Corundum-mullite with fracture toughness of 9.44 MPa.m-1/2 could be obtained under the optimized conditions, i.e. sintering temperature of 1400°C, 4.8 wt.% of AlF3 and 5.8 wt.% of V2O5. The results showed that it was feasible to prepare corundum-mullite toughened by in-situ synthesized mullite whiskers by the optimized parameters. In addition, an accurate model based on response surface method was proposed to predict the experimental results.


2012 ◽  
Vol 62 (4) ◽  
pp. 497-513 ◽  
Author(s):  
Simon Kukec ◽  
Franc Vrečer ◽  
Rok Dreu

The objective of this work was to investigate the influence of selected individual variables (binder content, inlet air temperature, and product endpoint temperature) of in situ fluid bed melt granulation on the granule particle size distribution and percentage of dissolved carvedilol using a three-factor, five-level circumscribed central composite design. Increased binder content had the effect of increasing the granule particle size and drug dissolution rate. The effect of inlet air temperature and product endpoint temperature was found to be more pronounced in case of granule particle size parameters. Within the studied intervals, the optimal quantity of binder as well as optimal process parameters were identified and validated using response surface methodology. Utilizing these optimal process and formulation parameters, successful scaling up of the fluid bed melt granulation process was carried out. Granule characteristics obtained at pilot scale are comparable to those obtained at laboratory scale.


Sign in / Sign up

Export Citation Format

Share Document