Influence of MTHFR C677T gene polymorphism in the development of cardiovascular disease in Egyptian patients with rheumatoid arthritis

Gene ◽  
2017 ◽  
Vol 610 ◽  
pp. 127-132 ◽  
Author(s):  
Tarek A. Abd El-Aziz ◽  
Rasha H. Mohamed
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiovascular Disease ◽  
Gene Polymorphism ◽  
Mthfr C677t ◽  
Egyptian Patients

scholarly journals Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: The role of obesity and smoking

2009 ◽  
Vol 204 (1) ◽  
pp. 178-183 ◽  
Author(s):  
Vasileios F. Panoulas ◽  
Antonios Stavropoulos-Kalinoglou ◽  
Giorgos S. Metsios ◽  
Jacqueline P. Smith ◽  
Haralampos J. Milionis ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Cardiovascular Disease ◽  
Gene Polymorphism ◽  
Interleukin 6

scholarly journals Toll-like receptor (TLR9) -1486 T/C (rs187084) gene polymorphism in Egyptian patients with rheumatoid arthritis

2019 ◽  
Vol 41 (3) ◽  
pp. 173-176 ◽  
Author(s):  
Marwa K. Hegazy ◽  
Fatma A. Auf ◽  
Nanis O. Neseem ◽  
Mohammad F. Al-Harrass
Keyword(s):  
Rheumatoid Arthritis ◽  
Gene Polymorphism ◽  
Toll Like Receptor ◽  
Egyptian Patients

Association of DDAH2 gene polymorphism with cardiovascular disease in Egyptian patients

2011 ◽  
Vol 90 (1) ◽  
pp. 161-163 ◽  
Author(s):  
MOHAMED Z. GAD ◽  
SALLY I. HASSANEIN ◽  
SAHAR M. ABDEL-MAKSOUD ◽  
GAMAL M. SHABAN ◽  
KHALED ABOU-AISHA
Keyword(s):  
Cardiovascular Disease ◽  
Gene Polymorphism ◽  
Egyptian Patients

scholarly journals Association of SIRT-1 Gene Polymorphism and Vitamin D Level in Egyptian Patients With Rheumatoid Arthritis

2018 ◽  
Vol 10 (3) ◽  
pp. 189-195 ◽  
Author(s):  
Dina Sabry ◽  
Shereen Rashad Kaddafy ◽  
Ahmed Ali Abdelaziz ◽  
Abdelfattah Kasem Nassar ◽  
Mohamed Moneer Rayan ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Gene Polymorphism ◽  
Egyptian Patients

Association of interleukin-4 gene polymorphism and rheumatoid arthritis in Egyptian patients

2019 ◽  
Vol 3 (2) ◽  
pp. 308
Author(s):  
SehamM.S El Nakeeb ◽  
ReemM Ahmed ◽  
AlzahraaA Elsied ◽  
MohsenM Ali Elsied
Keyword(s):  
Rheumatoid Arthritis ◽  
Gene Polymorphism ◽  
Interleukin 4 ◽  
Egyptian Patients

scholarly journals Assessment of the −174G/C (rs1800795) and −572G/C (rs1800796) Interleukin 6 Gene Polymorphisms in Egyptian Patients with Rheumatoid Arthritis

2016 ◽  
Vol 4 (4) ◽  
pp. 574-577 ◽  
Author(s):  
Khalda Amr ◽  
Rehab El-Awady ◽  
Hala Raslan
Keyword(s):  
Rheumatoid Arthritis ◽  
Gene Polymorphism ◽  
Interleukin 6 ◽  
Promoter Region ◽  
Gene Polymorphisms ◽  
Egyptian Patients ◽  
Promoter Gene ◽  
Pcr Products ◽  
Healthy Control ◽  
Genotype And Allele Frequencies

AIM: This study aimed to investigate genotype and allele frequencies of −174 (rs1800795) and −572 (rs1800796) IL-6 promoter gene polymorphisms in Egyptian patients with rheumatoid arthritis (RA) in comparison to control group.METHODS: The study was conducted on 198 Egyptian subjects (99 RA patients and 99 healthy control).The promoter region of the IL-6 gene was amplified by PCR using DNAs from patients and the controls, and their PCR products were digested by suitable enzymes.RESULTS: No statistical differences were found in −572G/C genotype (P = 0.177) or allele (P = 0.147) frequencies between RA patients and controls. Significant differences were observed in −174G/C genotype (P ˂ 0.001) and allele (P ˂ 0.001) frequencies between RA patients and controls.CONCLUSION: A significant association of IL-6 −174G/C gene polymorphism and RA in Egyptian population was found with significantly higher frequencies of GC and CC genotypes and C allele in RA patients compared to controls. No association was found between IL-6 −572G/C gene polymorphism and RA.

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