Use of Extracorporeal Membrane Oxygenation as a Bridge to Primary Lung Transplant: 3 Consecutive, Successful Cases and a Review of the Literature

Extracorporeal membrane oxygenation is a safe modality of cardiorespiratory support for lung transplantation, with a reduction in coagulopathy and transfusion requirement when compared with cardiopulmonary bypass. In some scenarios, in lung transplantation, there are advantages to the use of cardiopulmonary bypass, which allows cardiac decompression, filtering of embolic air, easy addition and removal of volume, and a means to immediately reintroduce lost blood into circulation. We describe a novel circuit which allows safe and easy switch between modalities without prolonged interruption of flow. This circuit offers a safety net during surgery to minimise the risks influencing the use of extracorporeal membrane oxygenation.

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Extracorporeal membrane oxygenation for coronavirus disease 2019-associated acute respiratory distress syndrome: Report of two cases and review of the literature

World Journal of Clinical Cases ◽

10.12998/wjcc.v9.i8.1953 ◽

2021 ◽

Vol 9 (8) ◽

pp. 1953-1967

Author(s):

Jun-Lin Wen ◽

Qi-Zhe Sun ◽

Zhou Cheng ◽

Xiao-Zu Liao ◽

Li-Qiang Wang ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Extracorporeal Membrane Oxygenation ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Distress Syndrome ◽

Review Of The Literature ◽

Membrane Oxygenation ◽

Syndrome Report

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Central versus peripheral cannulation of extracorporeal membrane oxygenation support during double lung transplant for pulmonary hypertension

European Journal of Cardio-Thoracic Surgery ◽

10.1093/ejcts/ezy089 ◽

2018 ◽

Vol 54 (2) ◽

pp. 341-347 ◽

Cited By ~ 8

Author(s):

Matthieu Glorion ◽

Olaf Mercier ◽

Delphine Mitilian ◽

Alexandra De Lemos ◽

Lilia Lamrani ◽

...

Keyword(s):

Pulmonary Hypertension ◽

Extracorporeal Membrane Oxygenation ◽

Lung Transplant ◽

Membrane Oxygenation

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Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplant

Seminars in Respiratory and Critical Care Medicine ◽

10.1055/s-0041-1728795 ◽

2021 ◽

Vol 42 (03) ◽

pp. 380-391

Author(s):

John W. Stokes ◽

Whitney D. Gannon ◽

Matthew Bacchetta

Keyword(s):

Extracorporeal Membrane Oxygenation ◽

Lung Disease ◽

Respiratory Function ◽

Lung Transplant ◽

Practice Patterns ◽

Effective Strategy ◽

Membrane Oxygenation ◽

Technological Advances ◽

Physiologic Condition ◽

End Stage

AbstractExtracorporeal membrane oxygenation (ECMO) is a cardiopulmonary technology capable of supporting cardiac and respiratory function in the presence of end-stage lung disease. Initial experiences using ECMO as a bridge to lung transplant (ECMO-BTLT) were characterized by high rates of ECMO-associated complications and poor posttransplant outcomes. More recently, ECMO-BTLT has garnered success in preserving patients' physiologic condition and candidacy prior to lung transplant due to technological advances and improved management. Despite recent growth, clinical practice surrounding use of ECMO-BTLT remains variable, with little data to inform optimal patient selection and management. Although many questions remain, the use of ECMO-BTLT has shown promising outcomes suggesting that ECMO-BTLT can be an effective strategy to ensure that complex and rapidly decompensating patients with end-stage lung disease can be safely transplanted with good outcomes. Further studies are needed to refine and inform practice patterns, management, and lung allocation in this high-risk and fragile patient population.

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