scholarly journals Synthesis, morphological analysis, antibacterial activity of iron oxide nanoparticles and the cytotoxic effect on lung cancer cell line

Heliyon ◽  
2020 ◽  
Vol 6 (9) ◽  
pp. e04953 ◽  
Author(s):  
Subrata Das ◽  
Sangharaj Diyali ◽  
Gopal Vinothini ◽  
Balaji Perumalsamy ◽  
Gowdhami Balakrishnan ◽  
...  
Nanomedicine ◽  
2019 ◽  
Vol 14 (17) ◽  
pp. 2355-2371 ◽  
Author(s):  
Shivani Thoidingjam ◽  
Ashu Bhan Tiku

Aim: Present work was undertaken to fabricate iron oxide nanoparticles (IONPs) using a green approach for increased therapeutic efficacy. Materials & methods: Two types of IONPs were synthesized, one without any coating (IONPUC) and other coated with Phyllanthus emblica (Amla) fruit extract (IONPA). Both the IONPs were characterized using different techniques and therapeutic efficacy was evaluated in A549 human lung cancer cell line. Results: IONPA were smaller in size with better dispersibility compared with IONPUC. They induced increased reactive oxygen species production, higher DNA damage and apoptosis, which resulted in increased toxicity to cancer cells in comparison to IONPUC. Conclusion: Higher uptake of IONPA and active components coating the surface, may be responsible for the increased therapeutic efficacy in cancer cells.


2019 ◽  
Vol 22 ◽  
pp. 101381
Author(s):  
Suganya Mani ◽  
Karthik Natesan ◽  
Kavitha Shivaji ◽  
Mythili Gnanamangai Balasubramanian ◽  
Ponmurugan Ponnusamy

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0129874 ◽  
Author(s):  
Refilwe P. Molatlhegi ◽  
Alisa Phulukdaree ◽  
Krishnan Anand ◽  
Robert M. Gengan ◽  
Charlette Tiloke ◽  
...  

2021 ◽  
Vol 12 (4) ◽  
pp. 1
Author(s):  
RIESHY V ◽  
ANITHA ROY ◽  
S RAGHUNANDHAKUMAR ◽  
LAKSHMI THANGAVELU

2017 ◽  
Vol 41 ◽  
pp. 231-241 ◽  
Author(s):  
Arzu YILMAZTEPE ORAL ◽  
Haluk Barbaros ORAL ◽  
Mehmet SARIMAHMUT ◽  
Buse CEVATEMRE ◽  
Güven ÖZKAYA ◽  
...  

2011 ◽  
Vol 31 (10) ◽  
pp. 1091-1095
Author(s):  
Xiao-lin LI ◽  
Yan-fang ZHANG ◽  
Kai TANG ◽  
Ying TANG ◽  
Ruo-bing JIN ◽  
...  

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