Shenrong Wuzi Pill affects the pathway of thyroid hormone synthesis by targeting thyrotropin-releasing hormone receptor and altering cAMP production

2021 ◽  
pp. 100470
Author(s):  
Yu Jiao ◽  
Ran Hu ◽  
Sirong Hu ◽  
Binge Wang ◽  
Dehong Huang ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Hormone Receptor ◽  
Thyrotropin Releasing Hormone ◽  
Camp Production ◽  
Releasing Hormone ◽  
Hormone Synthesis ◽  
Thyroid Hormone Synthesis

scholarly journals Both Thyroid Hormone Receptor (TR)β1 and TRβ2 Isoforms Contribute to the Regulation of Hypothalamic Thyrotropin-Releasing Hormone

Endocrinology ◽  
2004 ◽  
Vol 145 (5) ◽  
pp. 2337-2345 ◽  
Author(s):  
Sandrine M. Dupré ◽  
Hajer Guissouma ◽  
Frédéric Flamant ◽  
Isabelle Seugnet ◽  
Thomas S. Scanlan ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Hormone Receptor ◽  
Thyroid Hormone Receptor ◽  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone

scholarly journals Critical role for thyroid hormone receptor β2 in the regulation of paraventricular thyrotropin-releasing hormone neurons

2001 ◽  
Vol 107 (8) ◽  
pp. 1017-1023 ◽  
Author(s):  
E. Dale Abel ◽  
Rexford S. Ahima ◽  
Mary-Ellen Boers ◽  
Joel K. Elmquist ◽  
Fredric E. Wondisford
Keyword(s):  
Thyroid Hormone ◽  
Hormone Receptor ◽  
Thyroid Hormone Receptor ◽  
Critical Role ◽  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone

Is thyrotropin-releasing hormone receptor involved in thyrotrope adaptation to starvation?

1987 ◽  
Vol 115 (3) ◽  
pp. 353-356 ◽  
Author(s):  
Jean-Noel Hugues ◽  
Bryan Wolf ◽  
Jacques Sebaoun ◽  
Nicole Buisson ◽  
Danièle Gourdji
Keyword(s):  
Body Weight ◽  
Thyroid Hormone ◽  
Binding Sites ◽  
Hormone Receptor ◽  
Negative Control ◽  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone ◽  
Increased Sensitivity ◽  
Trh Receptors

Abstract. The aim of the present study was to delineate the involvement of TRH receptors in the thyrotrope adaptation to starvation (i.e. plasma TSH and thyroid hormone decrease, increased sensitivity to T3) by measuring [3H]TRH binding in euthyroid, hypothyroid and T3-substituted rats (175 ng/100 g body weight). Our results show that in euthyroid rats, starvation does not significantly modify either the affinity or the number of pituitary binding sites. In hypothyroid and T3-substituted rats, starvation does not alter the negative control exerted by T3 on the number of TRH binding sites. Our data indicate that the adaptation of thyrotrope to starvation does not primarily result from alterations of TRH binding sites.

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