scholarly journals HIV/AIDS treatment and health related quality of life: Importance of knowing patients’ perspective

2013 ◽  
Vol 12 (1) ◽  
pp. 26-27 ◽  
Author(s):  
Imran Ahmed Syed ◽  
Syed Azhar Syed Sulaiman ◽  
Mohammad Azmi Hassali ◽  
Christopher K.C. Lee
Author(s):  
S. Cynthia Subhaprada ◽  
Shasank R. V. S. S. ◽  
T. Sivakala ◽  
S. Madhusai

Background: HIV/AIDS is known to affect an individual not only physically but also mentally, socially, and financially. It is a syndrome that builds a vacuum in a person affecting his/her life as a whole. Combined with ART, Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). The objective of this study is to assess health related quality of life of HIV/AIDS patients attending ART clinic Tertiary care hospital, GGH, Kurnool and to determine the association of socio-demographic and disease related variables with health related quality of life.Methods: A cross-sectional study was conducted from April 2019 to June 2019 involving 400 purposively selected HIV-positive patients of age >18 years, who were taking highly active anti-retroviral therapy for the past 6months from the ART center, GGH, Kurnool. After obtaining IEC clearance and informed consent, WHOQOL-BREF instrument was used for data collection. Data analysis was performed using IBM SPSS version 26.0.Results: Out of the 400 participants, 60% were males. The mean age of the participants was 38.5±10.54 years. Overall quality of life had a mean score of 69.71. Physical (82.57) and level of independence (78.78) domains showed higher mean score when compared to psychological (63.82), environmental (61.49) and Social (60.26) domains.Conclusions: Among study subjects 15.5% had excellent QoL (≥80), nearly 69.75% had good QoL (60-79) and 14.75% had poor QoL (<60). Low QoL scores were seen in the social domain, suggesting that more social interventions are required in this population.


2016 ◽  
Vol 21 (6) ◽  
pp. 1580-1587 ◽  
Author(s):  
Mary M. Mitchell ◽  
Trang Q. Nguyen ◽  
Sarina R. Isenberg ◽  
Allysha C. Maragh-Bass ◽  
Jeanne Keruly ◽  
...  

2005 ◽  
Vol 14 (2) ◽  
pp. 479-491 ◽  
Author(s):  
Joseph M. Mrus ◽  
Paige L. Williams ◽  
Joel Tsevat ◽  
Susan E. Cohn ◽  
Albert W. Wu

2017 ◽  
Vol 63 (5) ◽  
pp. 329-336 ◽  
Author(s):  
Sarah Tymchuk ◽  
Daniela Gomez ◽  
Noshin Koenig ◽  
M. John Gill ◽  
Esther Fujiwara ◽  
...  

Objective: Mood disorders and neurocognitive impairments are debilitating conditions among patients with HIV/AIDS. How these comorbidities interact and their relationships to systemic factors remain uncertain. Herein, we investigated factors contributing to depressive symptomatology (DS) in a prospective cohort of patients with HIV/AIDS in active care that included neuropsychological assessment. Methods: Among patients with HIV/AIDS receiving combination antiretroviral therapy (cART) and ongoing clinical assessments including measures of sleep, health-related quality of life (HQoL), neuropsychological testing, and mood evaluation (Patient Health Questionnaire–9 [PHQ-9]) were performed. Univariate and multivariate analyses were applied to the data. Results: In 265 persons, 3 categories of DS were established: minimal (PHQ-9: 0-4; n = 146), mild (PHQ-9: 5-9; n = 62), and moderate to severe (PHQ-9: 10+; n = 57). Low education, unemployment, diabetes, reduced adherence to treatment, HIV-associated neurocognitive disorders (HAND), low health-related quality of life (HQoL), reduced sleep times, and domestic violence were associated with higher PHQ-9 scores. Motor impairment was also associated with more severe DS. In a multinomial logistic regression model, only poor HQoL and shorter sleep duration were predictive of moderate to severe depression. In this multivariate model, the diagnosis of HAND and neuropsychological performance (NPz) were not predictive of DS. Conclusions: Symptoms of depression are common (45%) in patients with HIV/AIDS and represent a substantial comorbidity associated with multiple risk factors. Our results suggest that past or present immunosuppression and HAND are not linked to DS. In contrast, sleep quality and HQoL are important variables to consider in screening for mood disturbances among patients with HIV/AIDS and distinguishing them from neurocognitive impairments.


2011 ◽  
Vol 8 (1) ◽  
pp. 5 ◽  
Author(s):  
Allyson Ion ◽  
Wenjie Cai ◽  
Dawn Elston ◽  
Eleanor Pullenayegum ◽  
Fiona Smaill ◽  
...  

2018 ◽  
Vol 4 (2) ◽  
Author(s):  
Angga Wilandika

ABSTRAKHIV/AIDS merupakan salah satu penyakit yang dapat menyebabkan kematian pada penderitanya. Penyakit ini mengganggu kualitas hidup penderitanya. Terlebih lagi sampai saat ini penyakit HIV/AIDS belum ada obatnya. Meskipun demikian, penyakit HIV/AIDS dapat dikendalikan dengan penggunaan terapi antiretroviral. Saat ini terapi antiretroviral sudah banyak dikembangkan dan golongan terbaru yang dianggap cukup efektif mengendalikan gelaja HIV/AIDS yaitu Highly Active Anti-Retroviral Therapy (HAART). Artikel ini bertujuan untuk mengidentifikasi penggunaan HAART terhdap health related quality of life (HRQOL) atau kualitas hidup kesehatan dari orang dengan HIV/AIDS (ODHA). Penelusuran literatur dilakukan melalui database PubMed dan ProQuest Nursing and Allied Health Source (Januari 2005 – Oktober 2017), menggunakan kata kunci penelusuran “quality of life”, “helath related quality of life”, “HAART”, dan HIV/AIDS. Selain itu, artikel yang dipilih dibatasi hanya pada penelitian original. Hasil kajian mengungkapkan bahwa penggunaan HAART pada ODHA dapat menekan jumlah virus HIV yang berdampak meningkatkan kadar CD4 dalam tubuh. Penggunaan HAART dapat meningkatkan sistem kekebalan tubuh ODHA, sehingga usia penderita HIV/AIDS cenderung memanjang dan kualitas hidup pun menjadi lebih baik. Namun di sisi lain, penggunaan HAART yang dikonsumsi ODHA seumur hidup juga memiliki efek samping terkait toksisitas obat tersebut. Ada kalanya beberapa ODHA mengalami komplikasi dari penggunaan obat HAART tersebut. Oleh karena itu penggunaan obat HAART sebaiknya dilakukan secara teratur dengan pengawasan tim medis atau perawat yang kompeten dalam pemberian terapi antiretroviral.ABSTRACTHIV/AIDS is one disease that cause death. This disease can reduce the quality of life of peple living with HIV/AIDS (PLWHA). There is no cure for HIV/AIDS, until now. However, HIV/AIDS is a deadly disease and incureable, but this disease can be controlled with the use of antiretroviral therapy. Currently, antiretroviral therapy has been widely developed and the latest class was considered quite effective in controlling the HIV/AIDS is Highly Active Anti-Retroviral Therapy (HAART). This article aims to identify the use of HAART on health related quality of life (HRQOL) or the quality of life of PLWHA. The methode used was the literature review. The literature search was conducted through the PubMed and ProQuest Nursing and Allied Health Source (January 2005 – October 2017) databases, were searched using keyword  term "quality of life", "health related quality of life", "HAART" and “HIV/AIDS”. In addition, the selected article is limited only to original research. The study results revealed that the use of HAART in people living with HIV/AIDS could reduce the viral load, so that can increase the levels of CD4 in the body. HAART could improve the immune system of PLWHA, so the age of PLWHA tend to elongate and the quality of life can be better. However, the use of HAART also has side effects related to the toxicity of the drug. Some PLWHA experience complications from the use of HAART drugs. Therefore, the use of HAART drugs should be carried out regularly with the supervision of a medical team or nurse who is competent in the administration of antiretroviral drugs.


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