Synthesis, X-ray structure and biological activity of mono- and dinuclear copper complexes derived from N-{2-[(2-diethylamino(alkyl)imino)-methyl]-phenyl}-4-methyl-benzenesulfonamide

2021 ◽  
Vol 523 ◽  
pp. 120408
Author(s):  
Valery G. Vlasenko ◽  
Anatolii S. Burlov ◽  
Yurii V. Koshchienko ◽  
Alexandra A. Kolodina ◽  
Bogdan V. Chaltsev ◽  
...  
Keyword(s):  
Biological Activity ◽  
Copper Complexes ◽  
Dinuclear Copper ◽  
X Ray ◽  
Methyl Phenyl

scholarly journals Synthese und Struktur diastereomerer, zweikerniger Kupferkomplexe [1] / Synthesis and Structure of Diastereomerie Dinuclear Copper Complexes [1]

1994 ◽  
Vol 49 (10) ◽  
pp. 1410-1414 ◽  
Author(s):  
Rolf W. Saalfrank ◽  
Oliver Struck ◽  
Karl Peters ◽  
Hans Georg von Schnering
Keyword(s):  
Structure Analysis ◽  
Copper Complexes ◽  
Molar Ratio ◽  
Dinuclear Copper ◽  
X Ray ◽  
Dark Green ◽  
2D Polymer ◽  
Light Green

Abstract Depolymerisation of a copper(II)/pyrrolidine-based 2D -polymer 2 by 4,4′-bipyridyl [molar ratio: 2 (CuL2) : 1 (Bipy)] and recrystallisation of the reaction product leads to two visually distinguishable crystal charges, composed of dark green octahedra meso-4 and light green rod-shaped crystals racem-5. Separation of the conglomerate of the morphologically different crystals is accomplished by pick out. The structure of the dinuelear complex racem-5 has been established unambigously by X-ray structure analysis. EPR and susceptibility measurements of mixtures of complex meso-4 and racem-5 indicate that there is no interaction be­tween the two copper(II) centres.

Synthesis, characterization and biological activity of copper complexes with pyridoxal thiosemicarbazone derivatives. X-ray crystal structure of three dimeric complexes

2004 ◽  
Vol 98 (2) ◽  
pp. 301-312 ◽  
Author(s):  
Marisa Belicchi Ferrari ◽  
Franco Bisceglie ◽  
Giorgio Pelosi ◽  
Pieralberto Tarasconi ◽  
Roberto Albertini ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Biological Activity ◽  
Copper Complexes ◽  
X Ray ◽  
Dimeric Complexes

scholarly journals Synthesis, magnetic behaviour, and X-ray structures of dinuclear copper complexes with multiple bridges. Efficient and selective catalysts for polymerization of 2,6-dimethylphenol

2007 ◽  
pp. 2405-2410 ◽  
Author(s):  
Ramaswamy Murugavel ◽  
Ramasamy Pothiraja ◽  
Nayanmoni Gogoi ◽  
Rodolphe Clérac ◽  
Lollita Lecren ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Magnetic Behaviour ◽  
Dinuclear Copper ◽  
X Ray

ChemInform Abstract: SYNTHESIS, CHARACTERIZATION, AND X-RAY MOLECULAR STRUCTURES OF MONO- AND DINUCLEAR COPPER COMPLEXES WITH 2,7-BIS(2-PYRIDYL)-1,8-NAPHTHYRIDINE

1985 ◽  
Vol 16 (7) ◽  
Author(s):  
W. R. TIKKANEN ◽  
C. KRUEGER ◽  
K. D. BOMBEN ◽  
W. L. JOLLY ◽  
W. C. KASKA ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Molecular Structures ◽  
Dinuclear Copper ◽  
X Ray

Synthesis, characterization, and x-ray molecular structures of mono- and dinuclear copper complexes with 2,7-bis(2-pyridyl)-1,8-naphthyridine

1984 ◽  
Vol 23 (22) ◽  
pp. 3633-3638 ◽  
Author(s):  
Wayne R. Tikkanen ◽  
Carl Krueger ◽  
Kenneth D. Bomben ◽  
William L. Jolly ◽  
William Kaska ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Molecular Structures ◽  
Dinuclear Copper ◽  
X Ray

Complexes of Cu (II) with a-Ketoglutaric Acid and 1- (o-tolyl) Biguanide Synthesis, characterization and biological Activity

2019 ◽  
Vol 70 (10) ◽  
pp. 3603-3610
Author(s):  
Madalina Mihalache ◽  
Cornelia Guran ◽  
Aurelia Meghea ◽  
Vasile Bercu ◽  
Ludmila Motelica ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Biological Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Copper Complexes ◽  
Substrate Adhesion ◽  
Inert Substrate

The three copper complexes having a-ketoglutaric acid (H2A) and 1- (o-tolyl) biguanide (TB) ligands have been synthesized and characterized. The proposed formulas for these complexes are: [Cu(TB)(HA)]Cl (C1), [Cu(TB)(HA)CH3COO]�H2O (C2) and [Cu(TB)(HA)](NO3) (C3) where HA represents deprotonated H2A. The complexes obtained were tested for antibacterial activity against Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 27853, antifungal activity on Candida albicans ATCC 10231 and antitumor activity on HeLa tumor cells. Due to the antitumor, antifungal, antimicrobial activity and inhibition of inert substrate adhesion, complexes synthesized could be used for potential therapeutic applications.

scholarly journals New Haloterpenes from the Marine Red Alga Laurencia papillosa: Structure Elucidation and Biological Activity

Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 35
Author(s):  
Mohamed Shaaban ◽  
Ghada S. E. Abou-El-Wafa ◽  
Christopher Golz ◽  
Hartmut Laatsch
Keyword(s):  
Biological Activity ◽  
Crude Extract ◽  
Structure Elucidation ◽  
Antimicrobial Activities ◽  
Red Alga ◽  
Spectroscopic Methods ◽  
X Ray Diffraction ◽  
X Ray ◽  
Chemical Structures ◽  
Terpene Derivatives

Analysis of the air-dried marine red alga Laurencia papillosa, collected near Ras-Bakr at the Suez gulf (Red Sea) in Egypt delivered five new halogenated terpene derivatives: aplysiolic acid (1), 7-acetyl-aplysiol (2), aplysiol-7-one (3), 11,14-dihydroaplysia-5,11,14,15-tetrol (5a), and a new maneonene derivative 6, named 5-epi-maneolactone. The chemical structures of these metabolites were characterized employing spectroscopic methods, and the relative and absolute configurations were determined by comparison of experimental and ab initio-calculated NMR, NOE, ECD, and ORD data, and by X-ray diffraction of 2 and 6. The antimicrobial activities of the crude extract and compounds 1–3, 5a and 6 were studied.

Isoselenocyanates: Synthesis and Their Use for Preparing Selenium-Based Heterocycles

Synthesis ◽  
2021 ◽  
Author(s):  
Stefan H. Bossmann ◽  
Raul Neri
Keyword(s):  
Biological Activity ◽  
Infectious Diseases ◽  
Cancer Cells ◽  
Multicomponent Reactions ◽  
Oxidative Cyclization ◽  
Biologically Active ◽  
Organoselenium Compounds ◽  
X Ray ◽  
Synthetic Work

AbstractIsoselenocyanates (ISCs) are a class of organoselenium compounds that have been recognized as potential chemotherapeutic and chemopreventative agents against cancer(s) and infectious diseases. ISC compounds are chemically analogous to their isosteric relatives, isothiocyanates (ITCs); however, they possess increased biological activity, such as enhanced cytotoxicity against cancer cells. ISCs not only serve as significant products, but also as precursors and essential intermediates for a variety of organoselenium compounds, such as selenium-containing heterocycles, which are biologically active. While syntheses of ISCs have become less difficult to accomplish, the syntheses of selenium-containing heterocycles are often difficult due to the use of highly toxic selenium reagents. Because of this, ISCs can serve as versatile reagents for the preparation of these heterocycles. In this review, the classical and recent syntheses of ISCs will be discussed, along with notable and recent synthetic work employing ISCs to access novel selenium-containing heterocycles.1 Introduction1.1 Selenium and Health2 Isoselenocyanates2.1 Preparation of Isoselenocyanates3 Selenium-Containing Heterocycles3.1 Notable Synthetic Work3.2 Recent Synthetic Work3.2.1 Synthesis of N-(3-Methyl-4-phenyl-3H-selenazol-2-ylidene)benzamide­ Derivatives3.2.2 Synthesis and X-ray Studies of Diverse Selenourea Derivatives3.2.3 Synthesis of Heteroarene-Fused [1,2,4]Thiadiazoles/Selenadiazoles via Iodine-Promoted [3+2] Oxidative Cyclization3.2.4 2-Amino-1,3-selenazole Derivatives via Base-Promoted Multicomponent Reactions4 Conclusion

Second-Generation Inhibitors for the Metalloprotease Neprilysin Based on Bicyclic Heteroaromatic Scaffolds: Synthesis, Biological Activity, and X-Ray Crystal-Structure Analysis

2005 ◽  
Vol 88 (4) ◽  
pp. 731-750 ◽  
Author(s):  
Stefan Sahli ◽  
Brian Frank ◽  
W. Bernd Schweizer ◽  
François Diederich ◽  
Denise Blum-Kaelin ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Biological Activity ◽  
Structure Analysis ◽  
Second Generation ◽  
Crystal Structure Analysis ◽  
X Ray
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