High-frequency repetitive transcranial magnetic stimulation does not change GABAA receptor-mediated inhibition in the rat hippocampus

2005 ◽  
Vol 1278 ◽  
pp. 303-306 ◽  
Author(s):  
Tomoaki Yuhi ◽  
Yukiko Fueta ◽  
Kazumasa Okada ◽  
Sadatoshi Tsuji
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Gabaa Receptor ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Rat Hippocampus

scholarly journals The effect of bilateral high frequency repetitive transcranial magnetic stimulation on cognitive functions in schizophrenia

2020 ◽  
Vol 22 ◽  
pp. 100183
Author(s):  
Mehmet Diyaddin Güleken ◽  
Taner Akbaş ◽  
Selime Çelik Erden ◽  
Veysel Akansel ◽  
Zeliha Cengiz Al ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Cognitive Functions ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation

Differentials effects of low and high frequency repetitive transcranial magnetic stimulation (rTMS) on sensory gating

2015 ◽  
Vol 8 (2) ◽  
pp. 386-387
Author(s):  
Emmanuelle Duprey ◽  
Clément Nathou ◽  
Grégory Simon ◽  
Sonia Dollfus ◽  
Olivier Etard
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Sensory Gating

scholarly journals Effect of Pulse Duration and Direction on Plasticity Induced by 5 Hz Repetitive Transcranial Magnetic Stimulation in Correlation With Neuronal Depolarization

2021 ◽  
Vol 15 ◽  
Author(s):  
Islam Halawa ◽  
Katharina Reichert ◽  
Aman S. Aberra ◽  
Martin Sommer ◽  
Angel V. Peterchev ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Motor Cortex ◽  
Pulse Duration ◽  
High Frequency ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Pass Filter ◽  
Low Pass Filter ◽  
Time Constants ◽  
Resting Motor Threshold

Introduction: High frequency repetitive transcranial magnetic stimulation applied to the motor cortex causes an increase in the amplitude of motor evoked potentials (MEPs) that persists after stimulation. Here, we focus on the aftereffects generated by high frequency controllable pulse TMS (cTMS) with different directions, intensities, and pulse durations.Objectives: To investigate the influence of pulse duration, direction, and amplitude in correlation to induced depolarization on the excitatory plastic aftereffects of 5 Hz repetitive transcranial magnetic stimulation (rTMS) using bidirectional cTMS pulses.Methods: We stimulated the hand motor cortex with 5 Hz rTMS applying 1,200 bidirectional pulses with the main component durations of 80, 100, and 120 μs using a controllable pulse stimulator TMS (cTMS). Fourteen healthy subjects were investigated in nine sessions with 80% resting motor threshold (RMT) for posterior-anterior (PA) and 80 and 90% RMT anterior-posterior (AP) induced current direction. We used a model approximating neuronal membranes as a linear first order low-pass filter to estimate the strength–duration time constant and to simulate the membrane polarization produced by each waveform.Results: PA and AP 5 Hz rTMS at 80% RMT produced no significant excitation. An exploratory analysis indicated that 90% RMT AP stimulation with 100 and 120 μs pulses but not 80 μs pulses led to significant excitation. We found a positive correlation between the plastic outcome of each session and the simulated peak neural membrane depolarization for time constants >100 μs. This correlation was strongest for neural elements that are depolarized by the main phase of the AP pulse, suggesting the effects were dependent on pulse direction.Conclusions: Among the tested conditions, only 5 Hz rTMS with higher intensity and wider pulses appeared to produce excitatory aftereffects. This correlated with the greater depolarization of neural elements with time constants slower than the directly activated neural elements responsible for producing the motor output (e.g., somatic or dendritic membrane).Significance: Higher intensities and wider pulses seem to be more efficient in inducing excitation. If confirmed, this observation could lead to better results in future clinical studies performed with wider pulses.

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