scholarly journals A hitherto study of relationship between left atrial volume and pressure in echocardiogram and length of left atrial branch of left circumflex artery in rheumatic heart disease

2015 ◽  
Vol 67 ◽  
pp. S8
Author(s):  
R. Manikanda Kumaran ◽  
K. Kannan ◽  
Ashok Victor ◽  
K. Tamilselvan ◽  
J. Cecily Mary Majella ◽  
...  
1998 ◽  
Vol 6 (2) ◽  
pp. 104-107
Author(s):  
Rajendar K Suri ◽  
Neerod K Jha ◽  
Harpreet Vohra ◽  
Ratna S Manjari ◽  
Rajam Venkateshwaran ◽  
...  

Analyses of lymphocyte subsets using flow cytometry were conducted to determine the significance of these cells in the pathogenesis of chronic rheumatic heart disease. Lymphocytes (B cells, T cells, CD4 cells, CD8 suppressor or cytotoxic T cells, activated T cells, and natural killer cells) were measured in blood and left atrial appendage samples of 30 patients with rheumatic heart disease and 10 patients with acyanotic congenital heart disease. Monoclonal fluorescent-labeled antibodies were used to identify various cells by flow cytometry. There was a significant increase in CD4 cells and activated T cells with a significant decrease in B cells in the left atrial appendage tissue of patients with rheumatic heart disease compared to those in the control group. There was no significant difference between the two groups in the distribution pattern of T lymphocytes in peripheral blood. These changes in rheumatic heart disease reflect an abnormal immunoregulatory mechanism with an ongoing enhanced immunological process continuing into the chronic phase of the disease. In our opinion, this persistent T cell response may lead to fresh damage to the myocardium and deformation of the heart valves.


2014 ◽  
Vol 2014 (apr30 1) ◽  
pp. bcr2014204370-bcr2014204370
Author(s):  
H. Mahla ◽  
K. K. Harlalka ◽  
S. Bhairappa ◽  
C. N. Manjunath

Circulation ◽  
1976 ◽  
Vol 54 (1) ◽  
pp. 146-153 ◽  
Author(s):  
M J Kelley ◽  
L P Elliott ◽  
S T Shulman ◽  
E M Ayoub ◽  
B E Victorica ◽  
...  

2010 ◽  
Vol 145 (2) ◽  
pp. 197-202 ◽  
Author(s):  
Jørgen Tobias Kühl ◽  
Klaus F. Kofoed ◽  
Jacob E. Møller ◽  
Sophia Hammer-Hansen ◽  
Thomas Kristensen ◽  
...  

2001 ◽  
Vol 18 (2) ◽  
pp. 159-161 ◽  
Author(s):  
Andrew Ying-Siu Lee ◽  
Michael Chich-Kuang Chang ◽  
Tien-Jen Chen ◽  
Wen-Fung Chang

Author(s):  
Abdul Qadir Khan Dall ◽  
Muhammed Kashif Shaikh ◽  
Syed Zulfiquar Ali Shah ◽  
Tarachand Devrajani ◽  
Abdul Salam Memon ◽  
...  

Background: Rheumatic Heart disease (RHD) is the leading cause of acquired heart disease and more prevalent in developing countries. The objective of the study was to determine the clinical and echocardiographic profiles of patients with rheumatic heart disease (RHD). Materials and Methods: All patients above the age of 12 years of either gender diagnosed with Rheumatic heart disease from January 2018 to December 2019 at tertiary care hospital, Hyderabad were enrolled in the study. Detailed patient data was obtained from the hospital records. Information regarding gender, age, Electrocardiogram findings, clinical and echocardiographic manifestations was obtained. Results: Throughout the two-year study period, a total of fifty patients with RHD were studied. The mean age of the population was 33.71 years. Females (64%) outnumbered males and 60% were rural population. The clinical features observed were fever (80%), joint pain (64%), palpitation (60%), breathlessness (90%) and chest pain (50%), tachycardia (60%), raised JVP (10%), hypertension (20%). The common echocardiographic findings observed were mitral stenosis (50%), mitral regurgitation (24%) and pulmonary hypertension (36%), left atrial enlargement (56%), and right atrial enlargement (16%) whereas the majority of the patients (70%) have ejection fraction between 40-50% and thrombus was identified in 15 (30%) patients respectively. Conclusion: Common clinical findings observed were breathlessness and fever while the common echocardiographic findings were mitral stenosis and regurgitation, pulmonary hypertension, and left atrial enlargement. Population-based screening by echocardiography could be a potential route for early screening of rheumatic heart disease.


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