Topical application of cashew gum or chlorhexidine gel reduces overexpression of proinflammatory genes in experimental periodontitis

2019 ◽  
Vol 128 ◽  
pp. 934-940 ◽  
Author(s):  
Hygor Ferreira-Fernandes ◽  
Marcos Aurélio L. Barros ◽  
Manoel D. Souza Filho ◽  
Jand Venes R. Medeiros ◽  
Daniel Fernando P. Vasconcelos ◽  
...  
2020 ◽  
Vol 10 (17) ◽  
pp. 6014
Author(s):  
Gianna Maria Nardi ◽  
Roberta Grassi ◽  
Guglielmo Campus ◽  
Maria Letizia Pareti ◽  
Dario Di Stasio ◽  
...  

Aim: This study aimed to assess the action of a chlorhexidine-based brush-on gel application in the treatment of plaque-related gingivitis. Methods: The enrollment involved consecutive patients diagnosed with plaque-induced gingivitis. Each participant’s full mouth plaque score and gingival index were recorded at the first appointment (t0) and at follow ups after 1 week (t1), 2 weeks (t2) and 3 weeks (t4). All patients were randomly sorted into two groups: A study group, who was given instruction to brush their gums daily with a chlorhexidine gel, and a control group who received a placebo gel. The two groups’ data at baseline were compared using a chi-square test, while the t-Student and Mann–Whitney tests were employed to analyze the index’s trends, both separately and compared. Results: In total, 30 patients were enrolled, 15 referring to the study group and 15 to the control group. The study group had an 87% decrease in their plaque score and an 84% decrease in their gingival index (p < 0.05). The control group displayed a reduction in plaque score and gingival index of 74% and 84%, respectively (p < 0.05). The plaque score decreased statistically more significantly in the study group than in the control group. Conclusion: Topical employment of a chlorhexidine-containing brush-on gel appears to be a useful home tool in the treatment of plaque-induced gingivitis, associated with professional debridement.


2018 ◽  
Vol 107 ◽  
pp. 1093-1101 ◽  
Author(s):  
Manoel D. Souza Filho ◽  
Jand V.R. Medeiros ◽  
Daniel F.P. Vasconcelos ◽  
Durcilene A. Silva ◽  
Ana C.M. Leódido ◽  
...  

Author(s):  
Victoria L. Wade ◽  
Winslow G. Sheldon ◽  
James W. Townsend ◽  
William Allaben

Sebaceous gland tumors and other tumors exhibiting sebaceous differentiation have been described in humans (1,2,3). Tumors of the sebaceous gland can be induced in rats and mice following topical application of carcinogens (4), but spontaneous mixed tumors of basal cell origin rarely occur in mice.


Obesity ◽  
2012 ◽  
Author(s):  
Gong-Rak Lee ◽  
Mi Kyung Shin ◽  
Dong-Joon Yoon ◽  
Ah-Ram Kim ◽  
Rina Yu ◽  
...  

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