Rhein incorporated silk fibroin hydrogels with antibacterial and anti-inflammatory efficacy to promote healing of bacteria-infected burn wounds

2022 ◽  
Author(s):  
Chuanjin Yin ◽  
Xiangsheng Han ◽  
Qingyang Lu ◽  
Xueju Qi ◽  
Chuanlong Guo ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Burn Wounds ◽  
Anti Inflammatory

scholarly journals Effect of silk fibroin peptide derived from silkworm Bombyx mori on the anti-inflammatory effect of Tat-SOD in a mice edema model

BMB Reports ◽  
2011 ◽  
Vol 44 (12) ◽  
pp. 787-792 ◽  
Author(s):  
Dae-Won Kim ◽  
Hyun-Sook Hwang ◽  
Duk-Soo Kim ◽  
Seung-Hoon Sheen ◽  
Dong-Hwa Heo ◽  
...  
Keyword(s):  
Bombyx Mori ◽  
Silk Fibroin ◽  
Edema Model ◽  
Anti Inflammatory ◽  
Silkworm Bombyx Mori ◽  
Inflammatory Effect

scholarly journals Silk fibroin-based nanotherapeutics: application in the treatment of colonic diseases

Nanomedicine ◽  
2019 ◽  
Vol 14 (17) ◽  
pp. 2373-2378 ◽  
Author(s):  
Shuangquan Gou ◽  
Yamei Huang ◽  
Junsik Sung ◽  
Bo Xiao ◽  
Didier Merlin
Keyword(s):  
Colon Cancer ◽  
Silk Fibroin ◽  
Drug Carrier ◽  
Colonic Diseases ◽  
Future Developments ◽  
Promising Strategy ◽  
Release Property ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Anti Inflammatory

The incidence of colonic diseases (e.g., inflammatory bowel diseases and colon cancer) is rapidly rising. Nanotherapeutic has been considered as a promising strategy in the treatment of colonic diseases. Silk fibroin (SF) has been widely used as a drug-carrier matrix. Interestingly, SF-based nanoparticles (SFNPs) have intrinsic anti-inflammatory activity, wound healing capacity and lysosomal environment-responsive drug-release property. With further investigations, the sequences of SF molecules could be precisely modified through chemical reactions or transgenic techniques to greatly improve the properties of SFNPs. Here, we review recent advances in the application of SFNPs toward the treatment of colonic diseases. We also discuss future developments that might improve the anti-inflammatory and anti-colon cancer activities of SF-based nanotherapeutics.

scholarly journals Intestinal anti-inflammatory effects of RGD-functionalized silk fibroin nanoparticles in trinitrobenzenesulfonic acid-induced experimental colitis in rats

2016 ◽  
Vol Volume 11 ◽  
pp. 5945-5958 ◽  
Author(s):  
Alba Rodriguez-Nogales ◽  
Francesca Algieri ◽  
Laura De Matteis ◽  
A. Abel Lozano-Perez ◽  
Jose Garrido-Mesa ◽  
...  
Keyword(s):  
Silk Fibroin ◽  
Experimental Colitis ◽  
Trinitrobenzenesulfonic Acid ◽  
Silk Fibroin Nanoparticles ◽  
Anti Inflammatory

Hybrid scaffolding strategy for dermal tissue reconstruction: a bioactive glass/chitosan/silk fibroin composite

RSC Advances ◽  
2016 ◽  
Vol 6 (24) ◽  
pp. 19887-19896 ◽  
Author(s):  
Danrong Li ◽  
Genlong Jiao ◽  
Wu Zhang ◽  
Xiaofeng Chen ◽  
Ruijian Ning ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Silk Fibroin ◽  
Tissue Response ◽  
Dermal Substitute ◽  
Burn Wounds ◽  
Dermal Tissue ◽  
Complex Process ◽  
Tissue Reconstruction ◽  
Scaffolding Strategy

Regeneration of deep burn wounds is a very complex process that strongly relies on the tissue response between the dermal substitute and the newly-formed dermis.

In Situ Forming Injectable Silk Fibroin Hydrogel Promotes Skin Regeneration in Full Thickness Burn Wounds

2018 ◽  
Vol 7 (24) ◽  
pp. 1801092 ◽  
Author(s):  
Dimple Chouhan ◽  
Tshewuzo-u Lohe ◽  
Pavan Kumar Samudrala ◽  
Biman B. Mandal
Keyword(s):  
Silk Fibroin ◽  
Skin Regeneration ◽  
Full Thickness ◽  
Burn Wounds ◽  
In Situ Forming
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