Hybrid scaffolding strategy for dermal tissue reconstruction: a bioactive glass/chitosan/silk fibroin composite

RSC Advances ◽  
2016 ◽  
Vol 6 (24) ◽  
pp. 19887-19896 ◽  
Author(s):  
Danrong Li ◽  
Genlong Jiao ◽  
Wu Zhang ◽  
Xiaofeng Chen ◽  
Ruijian Ning ◽  
...  

Regeneration of deep burn wounds is a very complex process that strongly relies on the tissue response between the dermal substitute and the newly-formed dermis.

2015 ◽  
Vol 7 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Wan Ting Sow ◽  
Dipali Devi ◽  
Kee Woei Ng ◽  
Biman B. Mandal ◽  
...  

Development of highly vascular dermal tissue-engineered skin substitutes with appropriate mechanical properties and cellular cues is in need for significant advancement in the field of dermal reconstruction.


2013 ◽  
Vol 9 (6) ◽  
pp. 6771-6782 ◽  
Author(s):  
Shuqin Yan ◽  
Qiang Zhang ◽  
Jiannan Wang ◽  
Yu Liu ◽  
Shenzhou Lu ◽  
...  

2004 ◽  
Vol 12 (1) ◽  
pp. A12-A12
Author(s):  
Morotomi Tadaaki ◽  
Kamiishi Hiroshi ◽  
Kubo Kentaro ◽  
Matsui Hiromichi ◽  
Kagawa Shizuko ◽  
...  

2014 ◽  
Vol 1 (2) ◽  
pp. 63-71 ◽  
Author(s):  
Xiaohong Wu ◽  
Fuhua Yan ◽  
Wei Liu ◽  
Hongbing Zhan ◽  
Wenrong Yang

Materials ◽  
2020 ◽  
Vol 13 (23) ◽  
pp. 5560
Author(s):  
Rachele Sergi ◽  
Devis Bellucci ◽  
Valeria Cannillo

Collagen, gelatin, silk fibroin, hyaluronic acid, chitosan, alginate, and cellulose are biocompatible and non-cytotoxic, being attractive natural polymers for medical devices for both soft and hard tissues. However, such natural polymers have low bioactivity and poor mechanical properties, which limit their applications. To tackle these drawbacks, collagen, gelatin, silk fibroin, hyaluronic acid, chitosan, alginate, and cellulose can be combined with bioactive glass (BG) nanoparticles and microparticles to produce composites. The incorporation of BGs improves the mechanical properties of the final system as well as its bioactivity and regenerative potential. Indeed, several studies have demonstrated that polymer/BG composites may improve angiogenesis, neo-vascularization, cells adhesion, and proliferation. This review presents the state of the art and future perspectives of collagen, gelatin, silk fibroin, hyaluronic acid, chitosan, alginate, and cellulose matrices combined with BG particles to develop composites such as scaffolds, injectable fillers, membranes, hydrogels, and coatings. Emphasis is devoted to the biological potentialities of these hybrid systems, which look rather promising toward a wide spectrum of applications.


2012 ◽  
Vol 25 (2) ◽  
pp. 159-164 ◽  
Author(s):  
Ville V. Meretoja ◽  
Teemu Tirri ◽  
Minna Malin ◽  
Jukka V. Seppälä ◽  
Timo O. Närhi

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