scholarly journals Maternal and neonatal complications during pregnancy in women with epilepsy

2016 ◽  
Vol 03 (02) ◽  
pp. 080-085
Author(s):  
R. Bansal ◽  
G. Jain ◽  
P. Kharbanda ◽  
M. Goyal ◽  
V. Suri
Keyword(s):  
Epidemiological Studies ◽  
Successful Management ◽  
Healthy Baby ◽  
Neonatal Complications ◽  
Neurological Problem ◽  
Harmful Effects ◽  
In Pregnancy

AbstractEpilepsy is the commonest serious neurological problem faced by obstetricians and gynaecologists. Epidemiological studies estimate epilepsy to complicate 0.3–0.7% of all pregnancies.1 2 The importance of epilepsy in pregnancy lies in the fact that many women with epilepsy (WWE) have to go through their pregnancy while taking antiepileptic (AED) drugs. Both the seizures and AEDs can have harmful effects on the mother as well the foetus. Thus, during pregnancy, the clinician faces dual challenge of controlling seizures as well as preventing teratogenicity of AEDs.1 In this review we discuss the possible impact of seizures as well as AEDs on mother as well as the child. We try to answer some of the commonest questions which are relevant to successful management of pregnancy and ensuring birth of a healthy baby.

Congenital malformations caused by psychotropic drugs in pregnancy

1994 ◽  
Vol 4 (4) ◽  
pp. 77-85
Author(s):  
G. de Cuypere ◽  
Ph. Rombaut ◽  
M. van Moffaert
Keyword(s):  
Valproic Acid ◽  
Side Effects ◽  
Psychotropic Drugs ◽  
Congenital Malformations ◽  
Epidemiological Studies ◽  
Teratogenic Effect ◽  
Teratogenic Effects ◽  
Harmful Effects ◽  
In Pregnancy

SummaryAfter a description of the harmful effects of psychotropic drugs as well as of the moments of vulnerability to any teratogenic effect, this paper reviews prospective, retrospective and epidemiological studies of the teratogenic effects of anticonvulsants (phenytoin, valproic acid, carbamazepine and barbiturates), lithium, anti-psychotics, benzodiazepines and anti-depressive agents. It is found that the results of these studies are not unequivocal. Only lithium and valproic acid are shown to be teratogenic. In cases where malformations of the fetus are observed, the treatment often consisted in a combination of various psychotropic drugs.The review is completed with data on the psychopharmacological problems during delivery and their side-effects on the newborn.

scholarly journals Asymptomatic uterine incarceration at term: Successful management of a rare complication in pregnancy

2018 ◽  
Vol 57 (5) ◽  
pp. 745-749 ◽  
Author(s):  
Po-Chao Hsu ◽  
Mu-Hsien Yu ◽  
Chen-Yu Wang ◽  
Yu-Kuen Wang ◽  
Chun-Kai Wang ◽  
...  
Keyword(s):  
Rare Complication ◽  
Successful Management ◽  
In Pregnancy

scholarly journals Glanzmann thrombasthenia in pregnancy: Optimising maternal and fetal outcomes

2016 ◽  
Vol 9 (4) ◽  
pp. 169-170 ◽  
Author(s):  
A Wijemanne ◽  
I Watt-Coote ◽  
S Austin
Keyword(s):  
Intracranial Haemorrhage ◽  
Autosomal Recessive ◽  
Postpartum Haemorrhage ◽  
Multidisciplinary Care ◽  
Maternal Outcomes ◽  
Fetal Outcomes ◽  
Glanzmann Thrombasthenia ◽  
Neonatal Complications ◽  
Alloimmune Thrombocytopenia ◽  
In Pregnancy

Glanzmann thrombasthenia is a rare autosomal recessive haemorrhagic disorder. The risks of miscarriage, antepartum and postpartum haemorrhage, and neonatal complications are all increased in individuals presenting with the disease in pregnancy. Some individuals may develop antibodies to platelet glycoproteins; the presence of these antibodies is a rare cause of neonatal alloimmune thrombocytopenia and potential intracranial haemorrhage. Multidisciplinary care is paramount for ensuring optimal fetal and maternal outcomes in such cases. We report a case of neonatal alloimmune thrombocytopenia secondary to maternal Glanzmann thrombasthenia in pregnancy.

scholarly journals Incidence and prevalence of iron deficiency anaemia

2018 ◽  
pp. 78-81
Author(s):  
V. E. Zhorova ◽  
E. G. Khilkevich
Keyword(s):  
Adverse Effect ◽  
Iron Deficiency ◽  
General Condition ◽  
Iron Deficiency Anaemia ◽  
Ferric Iron ◽  
Clinical Manifestations ◽  
Iron Supplements ◽  
Deficiency Anaemia ◽  
Neonatal Complications ◽  
In Pregnancy

Iron deficiency anaemia (IDA) is one of the most common complications in pregnancy. It is known that IDA has an adverse effect on the condition of the mother, fetus and new-borns. The article presents modern views of the aetiology, pathogenesis, prevalence of iron deficiency anaemia, describes the clinical manifestations of this condition. The rational of treatment of IDA with modern ferric iron supplements is substantiated. It is shown that IDA therapy in pregnant and puerperal women with Maltofer is highly effective, leads to normalization of hemogram parameters, improvement of general condition, and reduction of obstetric and neonatal complications.

Obesity in pregnancy

2020 ◽  
pp. 439-454
Author(s):  
Huda Al-Foudri ◽  
Stuart Davies ◽  
Abrie Theron
Keyword(s):  
Obese Woman ◽  
Epidemiological Studies ◽  
Morbidly Obese ◽  
Antenatal Screening ◽  
Screening Criteria ◽  
Obesity In Pregnancy ◽  
Labour Ward ◽  
Manual Handling ◽  
Body Mass Index Classification ◽  
In Pregnancy

Epidemiological studies show the incidence of obesity in pregnancy to be increasing, and the management of the morbidly obese woman on labour ward can be a challenge for anaesthetists. The chapter defines obesity, body mass index, classification, and prevalence, and reviews the physiological effects of obesity on the respiratory, cardiovascular, gastrointestinal, renal, endocrine, and haematological systems, as well as pharmacokinetic changes. Both fetal and maternal morbidities are listed followed by management proposals in the antenatal, peripartum, and postpartum periods. This includes antenatal screening, criteria for anaesthetic referral for assessment and what this should include to plan for delivery. Suggestions for management during labour and during an operative delivery are made. Attention is given to the ramped position and enhanced pre-oxygenation prior to induction of general anaesthesia with CPAP and THRIVE. Practical considerations and technical challenges are discussed and include manual handling, IV access, monitoring, regional techniques, and previous bariatric surgery.

Pregnancy-Preserving Laparoscopic Treatment of Acute Hemoperitoneum Following Lutein Cyst Rupture in Early Gestation

2019 ◽  
Vol 223 (02) ◽  
pp. 109-112
Author(s):  
Rafał Watrowski
Keyword(s):  
Case Report ◽  
Laparoscopic Approach ◽  
Postoperative Recovery ◽  
Absorbable Suture ◽  
Laparoscopic Treatment ◽  
Healthy Baby ◽  
Early Gestation ◽  
Cyst Rupture ◽  
Hemoglobin Drop ◽  
In Pregnancy

AbstractAcute hemoperitoneum (AHP) in early gestation is commonly treated via laparotomy. A ruptured corpus luteum (CL) cyst is a rare cause of AHP in pregnancy. This case report describes a 33-year-old, hemodynamically stable G2/P1 who presented at 5+5 gestational weeks with an acute abdomen due to ruptured CL cyst (7 cm). Emergent laparoscopy was performed. After evacuation of 1 L of hemoperitoneum, an atraumatic hemostasis was obtained without diathermy by use of hemostatic matrix (Floseal®). The ovary was reformed with an absorbable suture under preservation of CL. The postoperative recovery was uncomplicated. The hemoglobin drop was 2.8 g/dl. Further pregnancy course was uneventful. A healthy baby (2860 g) was delivered vaginally at 38+3 weeks of gestation. Conclusion Laparoscopic approach to AHP in early pregnancy is suitable. CL preservation is feasible by use of atraumatic hemostatics.

scholarly journals Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Santiago Bernal-Macías ◽  
Laura-Marcela Fino-Velásquez ◽  
Felipe E. Vargas-Barato ◽  
Lucio Guerra-Galue ◽  
Benjamín Reyes-Beltrán ◽  
...  
Keyword(s):  
Platelet Count ◽  
Pregnant Woman ◽  
Antiphospholipid Antibodies ◽  
First Trimester ◽  
Pharmacological Treatments ◽  
Autoimmune Thrombocytopenia ◽  
Baby Girl ◽  
Platelet Destruction ◽  
Healthy Baby ◽  
In Pregnancy

Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphospholipid antibodies. The disease was refractory to pharmacological treatments but had a favourable response to splenectomy. The patient carried the pregnancy to term without complication and gave birth to a healthy baby girl.

scholarly journals Pathophysiology of meningioma growth in pregnancy

Open Medicine ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. 195-200 ◽  
Author(s):  
Tibor Hortobágyi ◽  
János Bencze ◽  
Balázs Murnyák ◽  
Mahan C. Kouhsari ◽  
László Bognár ◽  
...  
Keyword(s):  
Elderly Women ◽  
Rare Complication ◽  
Serum Levels ◽  
Epidemiological Studies ◽  
Pituitary Hormones ◽  
Placental Lactogen ◽  
Biological Behaviour ◽  
Peritumoral Brain Edema ◽  
Endothelial Growth Factor ◽  
In Pregnancy

AbstractMeningioma is among the most frequent brain tumours predominantly affecting elderly women. Epidemiological studies have shown that at the age of fertility the incidence is relatively low. The biological behaviour of meningioma in pregnancy is different from other meningiomas. The possible explanation is rooted in the complex physiological changes and hormonal differences during pregnancy. The increased meningioma growth observed in pregnancy is presumably the result of endocrine mechanisms. These include increase in progesterone, human placental lactogen (hPL) and prolactin (PRL) serum levels. In contrast, levels of pituitary hormones such as follicle stimulating hormone (FSH), luteinizing hormone (LH) and human chorionic gonadotropin (hCG) produced by the placenta are decreasing in the mother prior to childbirth. Besides, vascular factors also play a crucial role. Peritumoral brain edema (PTBE), with well-known causative association with vascular endothelial growth factor (VEGF), can often be seen both with imaging and in the surgical specimens. Our aim is to assess published research on this topic including diagnostic and therapeutic guidelines, and to provide a clinically useful overview on the pathophysiology and biological behaviour of this rare complication of pregnancy.

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