Comparative Study of Tinea Pedis and Onychomycosis Between Type 2 Diabetic Patients and a Non-Diabetic Control Group in the Northern Iran

Background: Immune mediated destruction of pancreatic beta cell in type-I diabetes is well established but its’ role in young type-2 diabetic patients is still not conclusive. These young diabetic patients pass through several stages where they do not need insulin but found to have serum autoantibody against islets cell and even become dependent on insulin for survival in course of time. This study aims to find the presence of islets cell auto-antibodies (ICA) and autoantibody to glutamic acid decarboxylase-65 (GAD-65) in non-insulin requiring young diabetic patients of Bangladesh. Objective: To evaluate the presence of ICA and GAD-65 between the non-insulin requiring young type-2 diabetic patients and compare with the non-diabetic control group. Method: This case control study was carried out at the Department of Immunology, BIRDEM General Hospital, Dhaka for a period of one year from July 2013, A total of 120 non-insulin requiring (≥12 months) young type-2 diabetic patients and 60 age, sex matched non-diabetic were enrolled as control subjects following inclusion and exclusion criteria. ICA and GAD-65 tests were performed by enzyme linked immune-sorbent assay (ELISA) method by using kits from DRG Inc. International, USA. Results: In this study statistically significant difference found between non insulin requiring young diabetic patients and non diabetic control in respect of positive ICA result (p=0.015). The moderately strong negative association was found between different age of onset of diabetes mellitus and value of ICA level (r=-0.45). Only 20-24 years age group showed statistically significant difference between patient and control (p=0.013). Statistically significant difference was not found in GAD-65 values of non insulin requiring young diabetic patients and non diabetic controls (p=0.441). Conclusion: This study revealed that there is significant difference present in respect of ICA among non-insulin requiring young diabetic patients and non-diabetic controls. Therefore, autoimmune pathogenesis of beta cell killing by producing ICA against islets cell take place in young type-2 diabetic patients. Bangladesh Med Res Counc Bull 2020; 46(2): 104-108

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A randomized, open-labelled, parallel, comparative study of the efficacy and tolerability of rosuvastatin in low-density lipoprotein-cholestrol reduction using different dosing regimens of 5 mg daily, 10 mg daily and 10 mg on alternate days in Hong Kong Chinese type 2 diabetic patients

http://isrctn.org/> ◽

10.1186/isrctn72526711 ◽

2012 ◽

Author(s):

Francis C.C. Chow

Keyword(s):

Comparative Study ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Hong Kong Chinese ◽

Diabetic Patients ◽

Low Density ◽

Type 2 Diabetic Patients ◽

Dosing Regimens ◽

Type 2 Diabetic

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Comparative study of the concentration of salivary and blood glucose in type 2 diabetic patients

Journal of Oral Science ◽

10.2334/josnusd.52.293 ◽

2010 ◽

Vol 52 (2) ◽

pp. 293-298 ◽

Cited By ~ 42

Author(s):

Ana Carolina U. Vasconcelos ◽

Maria Sueli M. Soares ◽

Paulo C. Almeida ◽

Teresa C. Soares

Keyword(s):

Blood Glucose ◽

Comparative Study ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Type 2 Diabetic

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Olfactory disfunction and diabetic complications in type 2 diabetic patients: a pilot study

Endocrine ◽

10.1007/s12020-021-02897-6 ◽

2021 ◽

Author(s):

Francesco Mozzanica ◽

Anna Ferrulli ◽

Stela Vujosevic ◽

Alessandro Montuori ◽

Arianna Cardella ◽

...

Keyword(s):

Regression Analysis ◽

Diabetic Complications ◽

Control Group ◽

Subjective Perception ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Significant Difference ◽

Olfactory Abilities ◽

Type 2 Diabetic

Abstract Purpose Scarce information on the prevalence and characteristics of olfactory disfunction (OD) in type 2 diabetic (T2D) patients are available. The aims of this study were (1) to assess the olfactory function in T2D patients and to compare it with a control group of individuals without T2D, and (2) to evaluate the differences in OD within T2D patients according to the presence of diabetic complications. Methods A group of 39 T2D patients and a control group of 39 healthy individuals were enrolled. Each subject underwent an evaluation of the olfactory performance using the Sniffing Olfactory Screening Test (SOST) and completed a questionnaire assessing the subjective perception of olfaction. According to the presence of diabetic complications, the group of T2D patients was divided into two subgroups. Non-parametric tests and regression analysis were used for statistical analysis. Results No differences in the subjective perception of olfaction were demonstrated among T2D patients (with and without complications) and controls. A significant difference for the SOST score was demonstrated among the different groups. In particular, OD was more frequent in T2D patients than in controls. In addition, OD was far more frequent in T2D patients with complications. Regression analysis did not demonstrate any significant association between OD and clinical/demographic characteristics of T2D patients. Conclusion T2D patients were more frequently affected by OD. The subgroup analysis suggested a possible relationship between OD and diabetic complications since patients with T2D diabetic complications demonstrated lower olfactory abilities than controls subjects and T2D patients without diabetic complications.

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Evaluation of urinary L-FABP as an early marker for diabetic nephropathy in type 2 diabetic patients

Journal of Medical Biochemistry ◽

10.2478/jomb-2019-0037 ◽

2019 ◽

Vol 0 (0) ◽

Cited By ~ 1

Author(s):

Duong Thi Thuy Ngan ◽

Nguyen Gia Binh ◽

Le Thi Huong Lan ◽

Cuc Thi Thu Nguyen ◽

Phung Thanh Huong

Keyword(s):

Renal Function ◽

Diabetic Nephropathy ◽

Early Detection ◽

Urinary Albumin ◽

Control Group ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Fatty Acid Binding ◽

Type 2 Diabetic

Summary Background Albuminuria is the standard biomarker for the diagnosis of diabetic nephropathy (DN). However, some patients with persistent microalbuminuria still progress to chronic kidney disease, raising the question of finding a better biomarker. This study aimed to evaluate the correlation of urinary liver-type fatty acid-binding protein (L-FABP) levels with renal function and to compare the role of urinary albumin-to-creatinine ratio (ACR) with urinary L-FABP in early detection of DN in type 2 diabetic patients. Methods The cross-sectional study was done on 106 type 2 diabetic patients and 30 non-diabetic people. L-FABP was measured with the Latex enhanced immunoturbidimetric technique. Results There was a strong and negative correlation between the urine L-FABP levels and eGFR (r = -0.606, p<0.001). The urinary L-FABP levels were significantly higher (p<0.001) in the normoalbuminuria diabetic group than the non-diabetic control group. The ROC-curve analyses in the diabetic patients and the normoalbuminuria diabetic patients showed that the AUCL-FABP was remarkably higher (p<0.001) than the AUCACR. An optimal cutoff value of 5 mg L-FABP/g Cr (with the sensitivity of 98.1% and specificity of 90%) and of 4.3 mg L-FABP/g Cr (with the sensitivity of 100% and specificity of 86.67%) was set to detect DN in the diabetic patients and the normoalbuminuria diabetic patients, respectively. Conclusions The change in urinary L-FABP levels happened earlier than in urinary albumin during renal function impairment. Urinary L-FABP can be used as a better indicator than ACR for early detection of DN in type 2 diabetes.

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Prevalence of Substance Abuse and Related Factors in Type 2 Diabetic Patients Living in a Rural Area in Northern Iran

Journal of Clinical and Basic Research ◽

10.52547/jcbr.4.4.41 ◽

2020 ◽

Vol 4 (4) ◽

pp. 41-49

Author(s):

Mohammad Shokrzadeh ◽

Ali Savarolia ◽

Danial Jafari ◽

Reza Hoseinpoor ◽

Hajar Serayeloo ◽

...

Keyword(s):

Substance Abuse ◽

Rural Area ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Related Factors ◽

Northern Iran ◽

Type 2 Diabetic

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THE ASSOCIATION BETWEEN LIPID PROFILE AND WAIST TO HIP RATIOS IN TYPE - 1 AND TYPE - 2 DIABETIC PATIENTS – A COMPARATIVE STUDY

Journal of Evolution of Medical and Dental Sciences ◽

10.14260/jemds/2015/2016 ◽

2015 ◽

Vol 4 (81) ◽

pp. 14182-14189

Author(s):

Chalapathi Rao K N S S V ◽

Atluri Sridevi ◽

Siddnathi Narasinga Rao ◽

Naga Pavan Kumar M S ◽

Golve Srinivas ◽

...

Keyword(s):

Comparative Study ◽

Lipid Profile ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Type 2 Diabetic

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EFFECTS OF ISOLATED AND COMBINED EFFECTS OF AEROBIC DANCING AND RESISTANCE TRAINING ON RESTING PULSE RATE OF TYPE-2 DIABETIC PATIENTS

10.36106/ijar/3617913 ◽

2021 ◽

pp. 59-60

Author(s):

Maniazhagu Dharuman

Keyword(s):

Resistance Training ◽

Pulse Rate ◽

Control Group ◽

Diabetic Patients ◽

Combined Effects ◽

Type 2 Diabetic Patients ◽

Random Group ◽

Experimental Group ◽

Type 2 Diabetic

The purpose of study was to nd out the effects of isolated and combined effects of aerobic dancing and resistance training on resting pulse rate of type-2 diabetic patients. To achieve the purpose of the study, 60 type 2 diabetic patients with the age of 40-45 years from Karaikudi town, Sivaganga District, Tamilnadu were selected as subject at random. The study was formulated as pre and post test random group design, in which sixty subject were divided into four equal groups. The experimental group-1 (n=15, AD) underwent aerobic dancing, experimental group-2 (n=15, RT) underwent resistance training, experimental group – 3 (n=15, COM-T) underwent combined practice of aerobic dancing and resistance training and group-4 (n=15, CG) served as a control group. In this study, three training programme were adopted as independent variable, i.e., aerobic dancing, resistance training and combined training. The resting pulse rate was chosen as dependent variable. It was tested by number of beats per minute, scores recorded in number. The collected pre and post data was critically analyzed with apt statistical tool of analysis of co-variance. The Scheffe's post hoc test was used to nd out pair-wise comparisons between groups. The results of the present study proved that the three training interventions have signicantly altered the resting pulse rate.

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