Multifocal Glioblastoma Multiforme: Prognostic Factors and Patterns of Progression

: Glioblastoma multiforme (GBM) is characterized by poor prognosis despite an aggressive therapeutic strategy. In recent years, many advances have been achieved in the field of glioblastoma biology. : Here we try to summarize the main clinical and biological factors impacting clinical prognostication and therapy of GBM patients. From that standpoint, hopefully, in the near future, personalized therapies will be available.

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Treatment results, including clinical prognostic factors and MGMT gene promoter methylation, in patients with glioblastoma multiforme in Warmia and Mazury Oncology Centre

Współczesna Onkologia ◽

10.5114/wo.2011.24313 ◽

2011 ◽

Vol 4 ◽

pp. 198-202 ◽

Cited By ~ 2

Author(s):

Beata Czeremszyńska ◽

Mateusz Bujko ◽

Grażyna Ibron ◽

Agnieszka Onap-Karnak ◽

Sergiusz Nawrocki

Keyword(s):

Prognostic Factors ◽

Glioblastoma Multiforme ◽

Promoter Methylation ◽

Gene Promoter ◽

Treatment Results ◽

Mgmt Gene ◽

Oncology Centre

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P13.10 * SURGICAL TREATMENT FOR GLIOBLASTOMA MULTIFORME: OUTCOME AND ANALYSIS OF PROGNOSTIC FACTORS ESPECIALLY ORIENTED TO THE EXTENT OF SURGICAL RESECTION

Neuro-Oncology ◽

10.1093/neuonc/nou174.256 ◽

2014 ◽

Vol 16 (suppl 2) ◽

pp. ii67-ii68

Author(s):

L. Di Somma ◽

M. Iacoangeli ◽

L. Alvaro ◽

A. Di Rienzo ◽

V. Liverotti ◽

...

Keyword(s):

Prognostic Factors ◽

Surgical Treatment ◽

Glioblastoma Multiforme ◽

Surgical Resection ◽

Extent Of Surgical Resection

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Prognostic factors in glioblastoma multiforme

Arquivos Brasileiros de Neurocirurgia Brazilian Neurosurgery ◽

10.1055/s-0038-1625613 ◽

2010 ◽

Vol 29 (04) ◽

pp. 121-125 ◽

Cited By ~ 1

Author(s):

Leonardo Welling ◽

José Carlos Lynch ◽

Celestino Pereira ◽

Ricardo Andrade ◽

Fabiana Polycarpo Hidalgo ◽

...

Keyword(s):

Prognostic Factors ◽

Glioblastoma Multiforme ◽

Retrospective Analysis ◽

Tumor Volume ◽

Standard Treatment ◽

Karnofsky Performance Status ◽

Performance Status ◽

Surgical Techniques ◽

The Other ◽

Tumor Removal

Abstract Objective: To study if the prognosis variables such as age, the Karnofsky Performance Status (KPS), extension of tumor removal by surgery, radiotherapy and tumor volume influenced the survival of patients with glioblastoma multiforme (GBM). Method: Retrospective analysis of GBM patients operated at Hospital dos Servidores do Estado between 1998 and 2008. Results: We could observe that age, the KPS and radiotherapy influenced the survival. The other variables did not have any prognosis implications. Conclusions: Despite many researches and many improvements regarding the diagnosis and the surgical techniques, the survival of patients with GBM has not changed in the last 30 years and is a therapeutic challenge. The surgical resection followed by radiotherapy is the standard treatment for patients with GBM. The importance of each variable in the patient's prognosis is still to be established in the multivariate analyzes.

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