Impact of Percentage of Pre-Treatment Ideal Body Weight On Outcomes of Head and Neck Cancer Patients Receiving Definitive Concurrent Chemoradiation Therapy

Author(s):  
M.E. Platek ◽  
M. Cruz ◽  
N. Sharma ◽  
M. Burke ◽  
S. Popat ◽  
...  
2015 ◽  
Vol 14 (4) ◽  
pp. 343-352 ◽  
Author(s):  
Patrick Dawson ◽  
Amy Taylor ◽  
Chris Bragg

AbstractIntroductionHead and neck cancer patients receiving radiotherapy can experience a number of toxicities, including weight loss and malnutrition, which can impact upon the quality of treatment. The purpose of this retrospective cohort study is to evaluate weight loss and identify predictive factors for this patient group.Materials and methodsA total of 40 patients treated with radiotherapy since 2012 at the study centre were selected for analysis. Data were collected from patient records. The association between potential risk factors and weight loss was investigated.ResultsMean weight loss was 5 kg (6%). In all, 24 patients lost >5% starting body weight. Age, T-stage, N-stage, chemotherapy and starting body weight were individually associated with significant differences in weight loss. On multiple linear regression analysis age and nodal status were predictive.ConclusionYounger patients and those with nodal disease were most at risk of weight loss. Other studies have identified the same risk factors along with several other variables. The relative significance of each along with a number of other potential factors is yet to be fully understood. Further research is required to help identify patients most at risk of weight loss; and assess interventions aimed at preventing weight loss and malnutrition.


2015 ◽  
Vol 141 (0) ◽  
pp. 100-101
Author(s):  
Yuko Shimotatara ◽  
Toshikazu Shimane ◽  
Taisuke Nakamura ◽  
Kenichiro Kawaguchi ◽  
Aya Watanabe ◽  
...  

Toukeibu Gan ◽  
2020 ◽  
Vol 46 (3) ◽  
pp. 284-290
Author(s):  
Mutsukazu Kitano ◽  
Ryohei Fujiwara ◽  
Sena Horiguchi ◽  
Misako Nishihara ◽  
Ko Shiraishi ◽  
...  

2016 ◽  
Vol 130 (S2) ◽  
pp. S176-S180 ◽  
Author(s):  
P Clarke ◽  
K Radford ◽  
M Coffey ◽  
M Stewart

AbstractThis is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. The disease itself and the treatment can have far reaching effects on speech and swallow function, which are consistently prioritised by survivors as an area of concern. This paper provides recommendations on the assessments and interventions for speech and swallow rehabilitation in this patient group.Recommendations• All multidisciplinary teams should have rehabilitation patient pathways covering all stages of the patient's journey including multidisciplinary and pre-treatment clinics. (G)• Clinicians treating head and neck cancer patients should consult the National Cancer Rehabilitation Pathway for head and neck cancers. (G)• All head and neck cancer patients should have a pre-treatment assessment of speech and swallowing. (G)• A programme of prophylactic exercises and the teaching of swallowing manoeuvres can reduce impairments, maintain function and enable a speedier recovery. (R)• Continued speech and language therapist input is important in maintaining voice and safe and effective swallow function following head and neck cancer treatment. (R)• Disease recurrence must be ruled out in the management of stricture and/or stenosis. (R)• Continuous radial expansion balloons offer a safe, effective dilation method with advantages over gum elastic bougies. (R)• Site, length and completeness of strictures as well as whether they are in the presence of the larynx or not, need to be assessed when establishing the likelihood of surgically improved outcome. (G)• Primary surgical voice restoration should be offered to all patients undergoing laryngectomy. (R)• Attention to surgical detail and long-term speech and language therapist input is required to optimise speech and swallowing after laryngectomy. (G)• Patients should commence wearing heat and moisture exchange devices as soon as possible after laryngectomy. (R)


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