Lock-in thermography (LT), that is active infrared testing technology, mainly includes optical lock-in thermography (OLT) and ultrasound lock-in thermography (ULT). LT can be used to detect unbonds between honeycomb core and face sheet of sandwich structures. However, modulation frequency is an important influencing factor. In this paper, the principles of LT are represented, in experimental detections of simulated unbonds in honeycomb sandwich structures with Al-face sheet and CFRP-face sheet using OLT and ULT, detectability of OLT and ULT is compared and analyzed, effect of modulation frequency is researched and the optimal frequencies are obtained.