Vitiligo and serologic markers: Results from a case control study in a Spanish population

2011 ◽  
Vol 64 (2) ◽  
pp. AB142
2011 ◽  
Vol 68 (Suppl_1) ◽  
pp. A17-A18
Author(s):  
K. Papantoniou ◽  
G. Castano-Vinyals ◽  
B. P. Gomez ◽  
J. M. Altzibar ◽  
E. Ardanaz ◽  
...  

2007 ◽  
Vol 192 (1-2) ◽  
pp. 215-218 ◽  
Author(s):  
Elena Urcelay ◽  
Fiona Blanco-Kelly ◽  
Virginia de las Heras ◽  
Emilio G. de la Concha ◽  
Rafael Arroyo ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0159672 ◽  
Author(s):  
Inés Gómez-Acebo ◽  
Trinidad Dierssen-Sotos ◽  
Camilo Palazuelos ◽  
Beatriz Pérez-Gómez ◽  
Virginia Lope ◽  
...  

2011 ◽  
Vol 19 (2) ◽  
pp. 76-86 ◽  
Author(s):  
Silvia Jiménez-Sánchez ◽  
Rodrigo Jiménez-García ◽  
Valentín Hernández-Barrera ◽  
Manuel Villanueva-Martínez ◽  
Antonio Ríos-Luna ◽  
...  

2020 ◽  
Author(s):  
juan Trivino ◽  
A Ceba ◽  
E Rubio-Solsona ◽  
D Serra ◽  
I Sanchez-Guiu ◽  
...  

Abstract Background: In recent years, the identification of genetic and phenotypic biomarkers of cancer for prevention, early diagnosis and patient stratification has been a main objective of research in the field. Different multivariable models that use biomarkers have been proposed for the evaluation of individual risk of developing breast cancer. Methods: This is a case control study based on a population-based cohort. We describe and evaluate a multivariable model that incorporates 92 Single-nucleotide polymorphisms (SNPs) and five different phenotypic variables and which was employed in a Spanish population of 642 healthy women and 455 breast cancer patients. Results: Our model allowed us to stratify two groups: high and low risk of developing breast cancer. The 9th decile included 1% of controls vs 9% of cases, with an odds ratio (OR) of 12.9 and a p-value of 3.43E-07. The first decile presented an inverse proportion: 1% of cases and 9% of controls, with an OR of 0.097 and a p-value of 1.86E-08. Conclusions: These results indicate the capacity of our multivariable model to stratify women according to their risk of developing breast cancer. The major limitation of our analysis is the small cohort size. However, despite the limitations, the results of our analysis provide proof of concept in a poorly studied population, and opens up the possibility of using this method in the routine screening of the Spanish population.


2007 ◽  
Vol 8 (1) ◽  
Author(s):  
Concepción Núñez ◽  
Javier Oliver ◽  
Juan Luis Mendoza ◽  
María Gómez-García ◽  
Carlos Taxonera ◽  
...  

2015 ◽  
Vol 31 (9) ◽  
pp. 867-878 ◽  
Author(s):  
Kyriaki Papantoniou ◽  
Gemma Castaño-Vinyals ◽  
Ana Espinosa ◽  
Nuria Aragonés ◽  
Beatriz Pérez-Gómez ◽  
...  

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