scholarly journals Reply to: “Characterization of acute acro-ischemic lesions in non-hospitalized patients: A case series of 132 patients during the COVID-19 outbreak”

2020 ◽  
Vol 83 (3) ◽  
pp. e237-e239
Author(s):  
Giuseppe Ruggiero ◽  
Fabio Arcangeli ◽  
Torello Lotti ◽  
Orsola Ametrano ◽  
Cosimo Ruggiero ◽  
...  
Keyword(s):  
Case Series ◽  
Hospitalized Patients

scholarly journals Comment on “Characterization of acute acro-ischemic lesions in non-hospitalized patients: A case series of 132 patients during the COVID-19 outbreak”

2020 ◽  
Vol 83 (3) ◽  
pp. e241 ◽  
Author(s):  
Diego Fernandez-Nieto ◽  
Juan Jimenez-Cauhe ◽  
Ana Suarez-Valle ◽  
Oscar M. Moreno-Arrones ◽  
David Saceda-Corralo ◽  
...  
Keyword(s):  
Case Series ◽  
Hospitalized Patients

scholarly journals Emergence of Macrolide-Resistant Mycoplasma pneumoniae during an Outbreak in a Primary School: Clinical Characterization of Hospitalized Children

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 328
Author(s):  
Daniel Hubert ◽  
Roger Dumke ◽  
Stefan Weichert ◽  
Sybille Welker ◽  
Tobias Tenenbaum ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Case Series ◽  
Community Acquired Pneumonia ◽  
Hospitalized Patients ◽  
Macrolide Resistance ◽  
23S Rrna ◽  
Hospitalized Children ◽  
First Case ◽  
Potential Link

Mycoplasma pneumoniae (M. pneumoniae) is a common causative pathogen of community-acquired pneumonia. Here, we report the development of macrolide resistance during a school outbreak of severe M. pneumoniae infections in southwest Germany. We conducted a case series to assess the clinical and laboratory characteristics of hospitalized children with M. pneumonia infection and the prevalence of macrolide-resistant M. pneumoniae (MRMP) in this patient group. We retrospectively analyzed 23 children with serologically (19 patients) and/or PCR (eight patients) confirmed M. pneumoniae infection between October 2019 and December 2019. Most of the 15 hospitalized patients had lower respiratory tract infection (n = 10) and required oxygen therapy (83%). The median length of hospitalization was 7 days (range 3–10 days). In 8/15 patients (53.3%) azithromycin and in 4/15 (26.6%) clarithromycin treatment was applied. However, among the five patients for which extended molecular characterization was performed, sequencing of 23S rRNA revealed no mutation only in the first case, but development of macrolide resistance A2058G in four subsequent cases. Hence, we identified a cluster of hospitalized patients with emerging MRMP. Further studies are warranted to confirm a potential link between macrolide resistance and disease severity.

scholarly journals MACHINE-LEARNING CHARACTERIZATION OF SUBTLE HEMODYNAMIC INSTABILITY DIFFERENTIATES COVID-19 VERSUS SEASONAL INFLUENZA IN HOSPITALIZED PATIENTS

2021 ◽  
Vol 77 (18) ◽  
pp. 3087
Author(s):  
Naveena Yanamala ◽  
Nanda H. Krishna ◽  
Quincy Hathaway ◽  
Aditya Radhakrishnan ◽  
Srinidhi Sunkara ◽  
...  
Keyword(s):  
Machine Learning ◽  
Seasonal Influenza ◽  
Hemodynamic Instability ◽  
Hospitalized Patients

scholarly journals Clinical Frailty Score (CFS) versus Hospital Frailty Risk Score (HFRS) for predicting mortality and other adverse outcome in hospitalized patients with COVID‐19: Spanish case series

2021 ◽  
Author(s):  
Jose‐Manuel Ramos‐Rincon ◽  
Oscar Moreno‐Perez ◽  
Hector Pinargote‐Celorio ◽  
Jose‐Manuel Leon‐Ramirez ◽  
Mariano Andres ◽  
...  
Keyword(s):  
Risk Score ◽  
Adverse Outcome ◽  
Case Series ◽  
Hospitalized Patients ◽  
Frailty Score

scholarly journals Genetic characterization of skull base chondrosarcomas

2015 ◽  
Vol 123 (4) ◽  
pp. 1036-1041 ◽  
Author(s):  
Hiroki Kanamori ◽  
Yohei Kitamura ◽  
Tokuhiro Kimura ◽  
Kazunari Yoshida ◽  
Hikaru Sasaki
Keyword(s):  
Skull Base ◽  
Case Series ◽  
Bone Neoplasms ◽  
Comparative Genomic ◽  
Whole Genome ◽  
Whole Genome Analysis ◽  
Genetic Characteristics ◽  
Genome Study ◽  
Skull Base Chordomas

OBJECT Although chondrosarcomas rarely arise in the skull base, chondrosarcomas and chordomas are the 2 major malignant bone neoplasms occurring at this location. The distinction of these 2 tumors is important, but this distinction is occasionally problematic because of radiological and histological overlap. Unlike chordoma and extracranial chondrosarcoma, no case series presenting a whole-genome analysis of skull base chondrosarcomas (SBCSs) has been reported. The goal of this study is to clarify the genetic characteristics of SBCSs and contrast them with those of chordomas. METHODS The authors analyzed 7 SBCS specimens for chromosomal copy number alterations (CNAs) using comparative genomic hybridization (CGH). They also examined IDH1 and IDH2 mutations and brachyury expression. RESULTS In CGH analyses, the authors detected CNAs in 6 of the 7 cases, including chromosomal gains of 8q21.1, 19, 2q22-q32, 5qcen-q14, 8q21-q22, and 15qcen-q14. Mutation of IDH1 was found with a high frequency (5 of 7 cases, 71.4%), of which R132S was most frequently mutated. No IDH2 mutations were found, and immunohistochemical staining for brachyury was negative in all cases. CONCLUSIONS To the best of the authors' knowledge, this is the first whole-genome study of an SBSC case series. Their findings suggest that these tumors are molecularly consistent with a subset of conventional central chondrosarcomas and different from skull base chordomas.

scholarly journals Molecular Characterization of Ampicillin-Resistant Enterococcus faecium Isolates from Hospitalized Patients in Norway

2003 ◽  
Vol 41 (6) ◽  
pp. 2330-2336 ◽  
Author(s):  
R. Jureen ◽  
J. Top ◽  
S. C. Mohn ◽  
S. Harthug ◽  
N. Langeland ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Enterococcus Faecium ◽  
Hospitalized Patients

scholarly journals Connecting Hospitalized Patients with Their Families: Case Series and Commentary

2011 ◽  
Vol 2011 ◽  
pp. 1-7
Author(s):  
Kourosh Parsapour ◽  
Alexander A. Kon ◽  
Madan Dharmar ◽  
Amy K. McCarthy ◽  
Hsuan-Hui Yang ◽  
...  
Keyword(s):  
Close Contact ◽  
Case Series ◽  
Retrospective Chart Review ◽  
Family Satisfaction ◽  
Hospital Length ◽  
Hospitalized Patients ◽  
Patient Centered ◽  
Family Presence ◽  
Telemedicine Service ◽  
Personal Cost

The overall aim of this project was to ascertain the utilization of a custom-designed telemedicine service for patients to maintain close contact (via videoconference) with family and friends during hospitalization. We conducted a retrospective chart review of hospitalized patients (primarily children) with extended hospital length of stays. Telecommunication equipment was used to provide videoconference links from the patient's bedside to friends and family in the community. Thirty-six cases were managed during a five-year period (2006 to 2010). The most common reasons for using Family-Link were related to the logistical challenges of traveling to and from the hospital—principally due to distance, time, family commitments, and/or personal cost. We conclude that videoconferencing provides a solution to some barriers that may limit family presence and participation in care for hospitalized patients, and as a patient-centered innovation is likely to enhance patient and family satisfaction.

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