scholarly journals Assessment of laser-induced thermal damage in fresh skin with ex vivo confocal microscopy

2021 ◽  
Vol 84 (1) ◽  
pp. e19-e21
Author(s):  
Vinzent Kevin Ortner ◽  
Aditi Sahu ◽  
Merete Haedersdal ◽  
Milind Rajadhyaksha ◽  
Anthony Mario Rossi
2021 ◽  
pp. 101564
Author(s):  
Mohamed Hisham Aref ◽  
Ibrahim H. Aboughaleb ◽  
Abou-Bakr M. Youssef ◽  
Yasser H. El-Sharkawy

Author(s):  
Veronika Shavlokhova ◽  
Christa Flechtenmacher ◽  
Sameena Sandhu ◽  
Michael Vollmer ◽  
Jürgen Hoffmann ◽  
...  

2022 ◽  
Vol 11 (2) ◽  
pp. 393
Author(s):  
Alvin Wei Jun Teo ◽  
Hassan Mansoor ◽  
Nigel Sim ◽  
Molly Tzu-Yu Lin ◽  
Yu-Chi Liu

Keratoconus is the most common primary corneal ectasia characterized by progressive focal thinning. Patients experience increased irregular astigmatism, decreased visual acuity and corneal sensitivity. Corneal collagen crosslinking (CXL), a minimally invasive procedure, is effective in halting disease progression. Historically, keratoconus research was confined to ex vivo settings. In vivo confocal microscopy (IVCM) has been used to examine the corneal microstructure clinically. In this review, we discuss keratoconus cellular changes evaluated by IVCM before and after CXL. Cellular changes before CXL include decreased keratocyte and nerve densities, disorganized subbasal nerves with thickening, increased nerve tortuosity and shortened nerve fibre length. Repopulation of keratocytes occurs up to 1 year post procedure. IVCM also correlates corneal nerve status to functional corneal sensitivity. Immediately after CXL, there is reduced nerve density and keratocyte absence due to mechanical removal of the epithelium and CXL effect. Nerve regeneration begins after 1 month, with nerve fibre densities recovering to pre-operative levels between 6 months to 1 year and remains stable up to 5 years. Nerves remain tortuous and nerve densities are reduced. Corneal sensitivity is reduced immediately postoperatively but recovers with nerve regeneration. Our article provides comprehensive review on the use of IVCM imaging in keratoconus patients.


2020 ◽  
pp. 155335062093786
Author(s):  
Khiem Tran Dang ◽  
Shigeyuki Naka ◽  
Atsushi Yamada ◽  
Ken-ichi Mukaisho ◽  
Tohru Tani

Background. Ultrasonically activated dissectors (UADs) and radiofrequency-based devices have been considered excellent surgical devices because of their reliability and flexibility. Meanwhile, microwave-based devices have demonstrated potential with their unique heating mechanism. This study aims to compare the sealing function of a newly invented forceps-like microwave sealer (MS) with that of currently available UADs. Materials and Methods. MS and 2 examples of UADs (Harmonic Focus+ [HF+] and Sonicision [SNC]) were employed to perform mesenterectomies (in vivo) and sealing sizable vessels (ex vivo). Vessel diameter, seal time, burst pressure (BP), sealing completion, and instrument sticking were recorded. The samples underwent histological investigation for thermal damage evaluation. Results. During mesenterectomies, MS required 3 seconds and 30 W to secure a complete seal. The BP achieved by the MS seal was higher than that of HF+ and SNC on arteries (851 ± 203.7 vs 682.4 ± 287.3, P < .05; vs 833.1 ± 251.2 mmHg, P = .4523, respectively) but was not statistically different on veins (324.9 ± 203.5 vs 460.1 ± 320.3 vs 508.3 ± 350.7 mmHg, P = .215). In all trials, MS caused less sticking but exhibited similar heat-induced alterations to UADs. MS’s thermal spread was not statistically more extended than that of UADs on either arteries or veins. Conclusions. MS was capable of not only sealing tiny vessels but also achieving high-pressure endurance on sizable vessels. Its forceful grasping and synchronous heating process helped create solid stumps with an acceptable thermal spread.


Pancreatology ◽  
2001 ◽  
Vol 1 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Tobias Keck ◽  
Vanessa Campo-Ruiz ◽  
Andrew L. Warshaw ◽  
R. Rox Anderson ◽  
Carlos Fernández-del Castillo ◽  
...  

Cornea ◽  
2008 ◽  
Vol 27 (4) ◽  
pp. 439-445 ◽  
Author(s):  
Akira Kobayashi ◽  
Yasuhisa Ishibashi ◽  
Yosaburo Oikawa ◽  
Hideaki Yokogawa ◽  
Kazuhisa Sugiyama

2014 ◽  
Vol 92 ◽  
pp. 0-0
Author(s):  
M HAOUAS ◽  
C GUILLEMOT ◽  
D GRIVET ◽  
E CINOTTI ◽  
JL PERROT ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document