scholarly journals Cockroach allergen induces atopic dermatitis and up regulates DCIR expression in mast cell

2018 ◽  
Vol 141 (2) ◽  
pp. AB93
Author(s):  
Huang Yang ◽  
Xiaoyan Luo ◽  
Danh C. Do ◽  
Pei-song Gao
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Cockroach Allergen

Mast Cell Density and Subtypes in the Skin of Dogs with Atopic Dermatitis

1999 ◽  
Vol 120 (2) ◽  
pp. 187-197 ◽  
Author(s):  
M.M. Welle ◽  
T. Olivry ◽  
S. Grimm ◽  
M. Suter
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Cell Density ◽  
Mast Cell Density

Mast Cell-Nerve Interactions

Physiology ◽  
2000 ◽  
Vol 15 (5) ◽  
pp. 213-218 ◽  
Author(s):  
Omri Bauer ◽  
Ehud Razin
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Irritable Bowel Syndrome ◽  
Mast Cells ◽  
Interstitial Cystitis ◽  
Recent Literature ◽  
Irritable Bowel

Mutual associations between nerves and mast cells have been observed in normal conditions and in pathological ones such as human irritable bowel syndrome, atopic dermatitis, interstitial cystitis, and more. Here we review the recent literature in this field, putting emphasis on the enteric, skin, and urinary systems, and the pathophysiological implications of this interaction in them.

scholarly journals Effects of the Fruit Extract of Tribulus terrestris on Skin Inflammation in Mice with Oxazolone-Induced Atopic Dermatitis through Regulation of Calcium Channels, Orai-1 and TRPV3, and Mast Cell Activation

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Seok Yong Kang ◽  
Hyo Won Jung ◽  
Joo Hyun Nam ◽  
Woo Kyung Kim ◽  
Jong-Seong Kang ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Calcium Channels ◽  
Cell Activation ◽  
Inflammatory Cells ◽  
Skin Inflammation ◽  
Mast Cell Activation ◽  
Tribulus Terrestris ◽  
Symptom Scores ◽  
Safe Approach

Ethnopharmacological Relevance. In this study, we investigated the effects of Tribulus terrestris fruit (Leguminosae, Tribuli Fructus, TF) extract on oxazolone-induced atopic dermatitis in mice. Materials and Methods. TF extract was prepared with 30% ethanol as solvent. The 1% TF extract with or without 0.1% HC was applied to the back skin daily for 24 days. Results. 1% TF extract with 0.1% HC improved AD symptoms and reduced TEWL and symptom scores in AD mice. 1% TF extract with 0.1% HC inhibited skin inflammation through decrease in inflammatory cells infiltration as well as inhibition of Orai-1 expression in skin tissues. TF extract inhibited Orai-1 activity in Orai-1-STIM1 cooverexpressing HEK293T cells but increased TRPV3 activity in TRPV3-overexpressing HEK293T cells. TF extract decreased β-hexosaminidase release in RBL-2H3 cells. Conclusions. The present study demonstrates that the topical application of TF extract improves skin inflammation in AD mice, and the mechanism for this effect appears to be related to the modulation of calcium channels and mast cell activation. This outcome suggests that the combination of TF and steroids could be a more effective and safe approach for AD treatment.

scholarly journals Selective Cannabinoid Receptor-1 Agonists Regulate Mast Cell Activation in an Oxazolone-Induced Atopic Dermatitis Model

2016 ◽  
Vol 28 (1) ◽  
pp. 22 ◽  
Author(s):  
Gaewon Nam ◽  
Se Kyoo Jeong ◽  
Bu Man Park ◽  
Sin Hee Lee ◽  
Hyun Jong Kim ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Cell Activation ◽  
Cannabinoid Receptor ◽  
Mast Cell Activation ◽  
Cannabinoid Receptor 1

scholarly journals Capsiate Inhibits DNFB-Induced Atopic Dermatitis in NC/Nga Mice through Mast Cell and CD4+ T-Cell Inactivation

2015 ◽  
Vol 135 (8) ◽  
pp. 1977-1985 ◽  
Author(s):  
Ji H. Lee ◽  
Yun S. Lee ◽  
Eun-Jung Lee ◽  
Ji H. Lee ◽  
Tae-Yoon Kim
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
T Cell ◽  
Cd4 T Cell ◽  
Cell Inactivation

Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: a dermal microdialysis study

2000 ◽  
Vol 142 (6) ◽  
pp. 1114-1120 ◽  
Author(s):  
R. Rukwied ◽  
G. Lischetzki ◽  
F. Mcglone ◽  
G. Heyer ◽  
M. Schmelz
Keyword(s):  
Atopic Dermatitis ◽  
Mast Cell ◽  
Microdialysis Study
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