scholarly journals O3-08-05: Global and Local Interactions between Amyloid-B Pathology and Intrinsic Connectivity along the Spectrum of Alzheimer's Disease

2016 ◽  
Vol 12 ◽  
pp. P306-P306
Author(s):  
Lorenzo Pasquini ◽  
Gloria Benson ◽  
Martin Scherr ◽  
Igor Yakushev ◽  
Timo Grimmer ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Local Interactions ◽  
Intrinsic Connectivity ◽  
Global And Local

scholarly journals Intrinsic connectivity of the human brain provides scaffold for tau aggregation in clinical variants of Alzheimer's disease

2020 ◽  
Vol 16 (S1) ◽  
Author(s):  
Joseph Therriault ◽  
Tharick A. Pascoal ◽  
Melissa Savard ◽  
Sulantha Mathotaarachchi ◽  
Andréa Lessa Benedet ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Human Brain ◽  
Intrinsic Connectivity ◽  
Clinical Variants ◽  
Tau Aggregation

scholarly journals Global processing deficit in Alzheimer’s disease

2010 ◽  
Vol 3 (3) ◽  
pp. 22-26
Author(s):  
María J. Blanca ◽  
Teresa Rodrigo ◽  
Rebecca Bendayan
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Visual Information ◽  
Local Level ◽  
Global Processing ◽  
Attention Task ◽  
Visual Elements ◽  
Lower Accuracy ◽  
Divided Attention Task ◽  
Global And Local

Several studies of Alzheimer’s disease (AD) reveal an impaired capacity to integrate visual elements into global pictures, leading to a deficit in global processing of visual information. The aim of this paper was to explore global and local processing in people with AD at non-advanced stage. The Global and Local Attention Test (AGL; from the original Spanish: AGL-Atención global y local) was administered to a group of 100 participants with a mean age of 75.36 years. Fifty of them were AD patients at a mild or moderate stage, while the remainder comprised healthy elders. The AGL provides two scores that indicate speed and accuracy in analyzing global and local figures. Participants had to indicate the figures where the target appeared at either global or local levels in a divided attention task. The results showed lower accuracy in the AD group compared with controls. Also in the AD group, and in line with previous findings, accuracy in detecting the target was much lower at the global level than at the local level, thereby confirming the expected deficit in global processing associated with AD. This deficit did not vary according to sex or age.

scholarly journals Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain

2019 ◽  
Vol 23 ◽  
pp. 101848 ◽  
Author(s):  
Rik Ossenkoppele ◽  
Leonardo Iaccarino ◽  
Daniel R. Schonhaut ◽  
Jesse A. Brown ◽  
Renaud La Joie ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Intrinsic Connectivity ◽  
Intrinsic Connectivity Networks

scholarly journals Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk

2015 ◽  
Vol 12 (3) ◽  
pp. 233-243 ◽  
Author(s):  
Timothy J. Hohman ◽  
Jessica N. Cooke-Bailey ◽  
Christiane Reitz ◽  
Gyungah Jun ◽  
Adam Naj ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
African Americans ◽  
Disease Risk ◽  
Local Ancestry ◽  
Global And Local

Directed and divided attention in Alzheimer's disease: Impairment in shifting of attention to global and local stimuli

1992 ◽  
Vol 14 (6) ◽  
pp. 871-883 ◽  
Author(s):  
J. Vincent Filoteo ◽  
Dean C. Delis ◽  
Paul J. Massman ◽  
Theresa Demadura ◽  
Nelson Butters ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Divided Attention ◽  
Global And Local

O3-08-04: Tau Covariance Patterns in Alzheimer's Disease Patients Resemble Intrinsic Connectivity Networks in Young Adults

2016 ◽  
Vol 12 ◽  
pp. P305-P306
Author(s):  
Rik Ossenkoppele ◽  
Daniel R. Schonhaut ◽  
Jesse Brown ◽  
James P. O'Neil ◽  
Mustafa Janabi ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Young Adults ◽  
Intrinsic Connectivity ◽  
Intrinsic Connectivity Networks

scholarly journals Individual Correspondence of Amyloid-β and Intrinsic Connectivity in the Posterior Default Mode Network Across Stages of Alzheimer’s Disease

2017 ◽  
Vol 58 (3) ◽  
pp. 763-773 ◽  
Author(s):  
Lorenzo Pasquini ◽  
Gloria Benson ◽  
Michel J. Grothe ◽  
Lukas Utz ◽  
Nicholas E. Myers ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Default Mode Network ◽  
Amyloid Β ◽  
Default Mode ◽  
Intrinsic Connectivity

Global and local gray matter loss in mild cognitive impairment and Alzheimer's disease

NeuroImage ◽  
2004 ◽  
Vol 23 (2) ◽  
pp. 708-716 ◽  
Author(s):  
G.B. Karas ◽  
P. Scheltens ◽  
S.A.R.B. Rombouts ◽  
P.J. Visser ◽  
R.A. van Schijndel ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Gray Matter ◽  
Gray Matter Loss ◽  
Global And Local
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