Evaluation by the Bariatric Analysis and Reporting Outcome System Model of the Results of Patients with 1 Postoperative Year of Gastric Sleeve and Bypass for the Treatment of Obesity

Obesity is a complex and multifactorial disease. Its relationship with periodontal disease and other chronic diseases is well documented but the underlying mechanism is under investigation. It is quite difficult to say whether obesity predisposes an individual to periodontal disease or periodontal disease affects lipid metabolism, or both. The purpose of the study consists in evaluating the periodontal clinical parameters in obese patients diagnosed with chronic periodontitis, before and after surgical treatment of obesity through the procedure called gastric sleeve Our study consists of a group of 38 patients diagnosed with morbid obesity who were surgically treated by gastric sleeve surgery at the Surgery Department II of the County Emergency Clinical Hospital Targu Mures. Patients with pre-operative and psot-operative examination at 3 months and 6 months respectively in which either periodontal index were index of plaque, index of probing depth and index of bleeding on probing. Correlations between parondontal clinical indexes (PD, PI, BOP) were calculated before and after gastric sleeve at 3 and 6 months respectively. The bleeding on probing index (BOP) reveals a complete decrease in postoperative bleeding time. Patients at 3 months experience minor bleeding during testing and no longer showing bleeding at 6 months. The results provide evidence that there is a link between obesity and periodontitis, however the risk factors that aggravate these diseases should be clarified to elucidate the direction of this association.

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Functional characterization of human brown adipose tissue metabolism

Biochemical Journal ◽

10.1042/bcj20190464 ◽

2020 ◽

Vol 477 (7) ◽

pp. 1261-1286 ◽

Cited By ~ 3

Author(s):

Marie Anne Richard ◽

Hannah Pallubinsky ◽

Denis P. Blondin

Keyword(s):

Adipose Tissue ◽

Brown Adipose Tissue ◽

Functional Characterization ◽

Human Infants ◽

Positron Emission ◽

Brown Adipose ◽

Treatment Of Obesity ◽

And Function

Brown adipose tissue (BAT) has long been described according to its histological features as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the cold and found especially in hibernating mammals and human infants. Its presence in both hibernators and human infants, combined with its function as a heat-generating organ, raised many questions about its role in humans. Early characterizations of the tissue in humans focused on its progressive atrophy with age and its apparent importance for cold-exposed workers. However, the use of positron emission tomography (PET) with the glucose tracer [18F]fluorodeoxyglucose ([18F]FDG) made it possible to begin characterizing the possible function of BAT in adult humans, and whether it could play a role in the prevention or treatment of obesity and type 2 diabetes (T2D). This review focuses on the in vivo functional characterization of human BAT, the methodological approaches applied to examine these features and addresses critical gaps that remain in moving the field forward. Specifically, we describe the anatomical and biomolecular features of human BAT, the modalities and applications of non-invasive tools such as PET and magnetic resonance imaging coupled with spectroscopy (MRI/MRS) to study BAT morphology and function in vivo, and finally describe the functional characteristics of human BAT that have only been possible through the development and application of such tools.

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