scholarly journals Cathepsin Activity as a Biomarker for Early Human Colonic Dysplasia

2021 ◽  
Vol 233 (5) ◽  
pp. S244
Author(s):  
Dhavan Shah ◽  
Elias Gounaris ◽  
David J. Bentrem
Keyword(s):  
Cathepsin Activity ◽  
Early Human

THE ULTRASTRUCTURE OF THE HUMAN GRANULOSAL LUTEIN CELL OF THE FIRST TRIMESTER OF GESTATION

1968 ◽  
Vol 58 (3) ◽  
pp. 481-496 ◽  
Author(s):  
Poul Hjortkjær Pedersen ◽  
Jørgen Falck Larsen
Keyword(s):  
Endoplasmic Reticulum ◽  
Smooth Endoplasmic Reticulum ◽  
First Trimester ◽  
Corpora Lutea ◽  
Steroid Synthesis ◽  
Intracellular Location ◽  
Human Pregnancy ◽  
Subendothelial Space ◽  
Lutein Cell ◽  
Early Human

ABSTRACT The ultrastructure of granulosal lutein cells of 13 corpora lutea in early human pregnancy was studied. The predominant cytoplasmic element was the smooth endoplasmic reticulum. No convincing signs of degeneration of the lutein cells could be demonstrated within the first 14 weeks of pregnancy, as the mitochondria as well as the rough and smooth endoplasmic reticulum were well preserved. However, lysosomes may be slightly more numerous in older specimens and the subendothelial space increases with the age of gestation. A particular type of multilaminated structure one to five micron in diameter was observed, particularly in the earliest specimens. The possible intracellular location of steroid synthesis is discussed.

PROPRANOLOL-BLOCKADE OF VASOPRESSIN INDUCED INCREASE IN PLASMA PROGESTERONE IN EARLY HUMAN PREGNANCY

1971 ◽  
Vol 66 (2) ◽  
pp. 283-288 ◽  
Author(s):  
Petter Fylling
Keyword(s):  
Cyclic Amp ◽  
Uterine Cervix ◽  
Adenosine Monophosphate ◽  
First Trimester ◽  
Blocking Agent ◽  
Simultaneous Administration ◽  
Plasma Progesterone ◽  
Human Pregnancy ◽  
Peripheral Plasma ◽  
Early Human

ABSTRACT Following continuous dilation of the uterine cervix or intravenous infusion of vasopressin during the first trimester of human pregnancy, a marked increase in the peripheral plasma progesterone levels was observed. This effect was blocked by simultaneous administration of propranolol (Inderal®), a β-blocking agent. It is suggested that both these stimulating and inhibiting effects might be related to 3′, 5′-adenosine monophosphate (cyclic AMP). The results indicate the existence of β-receptors in steroid producing tissues.

Early human relations set the foundation for adult health and working life

2018 ◽  
Author(s):  
Alan Sinclair ◽  
Tam Baillie
Keyword(s):  
Well Being ◽  
Early Years ◽  
Adult Health ◽  
Human Relations ◽  
Rights Of The Child ◽  
Parents And Children ◽  
Evidence Analysis ◽  
Before School ◽  
Child Health Research ◽  
Early Human

Investing in early years is close to magic, without being magic. The United Nations has given greater prominence to the early years through a General Comment on the Convention on the Rights of the Child. Health research is gravitating to a view that adult physical and mental conditions have their origins in the womb and the earliest months and years of life. More than any other skills, employers want people who can talk, listen, and work with others: attributes that are largely picked up before school. Economists have demonstrated that the best return on investment in ‘education’ is in supporting parents and children, in the years before school. While evidence, analysis, and experience, which we review, points in one direction, it leads to three questions. Where are we now in child well-being and supporting parents and their very young children? Why are we not doing better? What can be done?

scholarly journals Fishing during the early human occupations of the Atacama Desert coast: what if we standardize the data?

2021 ◽  
Vol 13 (9) ◽  
Author(s):  
Sandra Rebolledo ◽  
Philippe Béarez ◽  
Débora Zurro
Keyword(s):  
Regional Analysis ◽  
Atacama Desert ◽  
Coastal Communities ◽  
Archaeological Sites ◽  
Common Component ◽  
Exploratory Approach ◽  
Data Heterogeneity ◽  
Terminal Pleistocene ◽  
Methodological Approaches ◽  
Early Human

Abstract The Atacama Desert coast (18–30° S) presents one of the earliest chronologies in the South America region, whose first occupations date from ~ 13,000 cal BP. Since that time, coastal and marine resources have been a common component at sites along the littoral zone. Fish species have been particularly important, as have the fishing technologies developed and used by the coastal communities. However, even though several archaeological sites have been studied, there is no systematic macro-regional analysis of early fisheries along the Atacama Desert coast. Furthermore, differences in theoretical and methodological approaches, as well as research objectives, hinder comparisons between ichthyoarchaeological assemblages. Here, we present a comparative analysis of the Atacama Desert fish data obtained from publications and gray literature from ten archaeological sites dating from the Terminal Pleistocene to the Early Holocene. Through the standardization of contextual and ichthyoarchaeological information, we compared data using NISP, MNI, and weight to calculate fish density, richness, and ubiquity, in order to identify similarities and differences between assemblages. This exploratory approach aims to contribute to studies of fish consumption in the area, as well as proposing new methodological questions and solutions regarding data heterogeneity in archaeozoology.

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