Machine learning algorithms based on signals from a single wearable inertial sensor can detect surface- and age-related differences in walking

2018 ◽  
Vol 71 ◽  
pp. 37-42 ◽  
Author(s):  
B. Hu ◽  
P.C. Dixon ◽  
J.V. Jacobs ◽  
J.T. Dennerlein ◽  
J.M. Schiffman
2021 ◽  
Author(s):  
Mandana Modabbernia ◽  
Heather C Whalley ◽  
David Glahn ◽  
Paul M. Thompson ◽  
Rene S. Kahn ◽  
...  

Application of machine learning algorithms to structural magnetic resonance imaging (sMRI) data has yielded behaviorally meaningful estimates of the biological age of the brain (brain-age). The choice of the machine learning approach in estimating brain-age in children and adolescents is important because age-related brain changes in these age-groups are dynamic. However, the comparative performance of the multiple machine learning algorithms available has not been systematically appraised. To address this gap, the present study evaluated the accuracy (Mean Absolute Error; MAE) and computational efficiency of 21 machine learning algorithms using sMRI data from 2,105 typically developing individuals aged 5 to 22 years from five cohorts. The trained models were then tested in an independent holdout datasets, comprising 4,078 pre-adolescents (aged 9-10 years). The algorithms encompassed parametric and nonparametric, Bayesian, linear and nonlinear, tree-based, and kernel-based models. Sensitivity analyses were performed for parcellation scheme, number of neuroimaging input features, number of cross-validation folds, and sample size. The best performing algorithms were Extreme Gradient Boosting (MAE of 1.25 years for females and 1.57 years for males), Random Forest Regression (MAE of 1.23 years for females and 1.65 years for males) and Support Vector Regression with Radial Basis Function Kernel (MAE of 1.47 years for females and 1.72 years for males) which had acceptable and comparable computational efficiency. Findings of the present study could be used as a guide for optimizing methodology when quantifying age-related changes during development.


2017 ◽  
Vol 42 ◽  
pp. 186-192 ◽  
Author(s):  
Füsun Er ◽  
Pınar Iscen ◽  
Sevki Sahin ◽  
Nilgun Çinar ◽  
Sibel Karsidag ◽  
...  

2019 ◽  
Vol 16 (9) ◽  
pp. 3840-3848
Author(s):  
Neeraj Kumar ◽  
Jatinder Manhas ◽  
Vinod Sharma

Advancement in technology has helped people to live a long and better life. But the increased life expectancy has also elevated the risk of age related disorders, especially the neurodegenerative disorders. Alzheimer’s is one such neurodegenerative disorder, which is also the leading contributor towards dementia in elderly people. Despite of extensive research in this field, scientists have failed to find a cure for the disease till date. This makes early diagnosis of Alzheimer’s very crucial so as to delay its progression and improve the condition of the patient. Various techniques are being employed for diagnosing Alzheimer’s which include neuropsychological tests, medical imaging, blood based biomarkers, etc. Apart from this, various machine learning algorithms have been employed so far to diagnose Alzheimer’s in its early stages. In the current research, authors compared the performance of various machine learning techniques i.e., Linear Discriminant Analysis (LDA), K-Nearest Neighbour (KNN), Naïve Bayes (NB), Support Vector Machines (SVM), Decision Trees (DT), Random Forests (RF) and Multi Layer Perceptron (MLP) on Alzheimer’s dataset. This paper experimentally demonstrated that normalization exhibits a predominant role in enhancing the efficiency of some machine learning algorithms. Therefore it becomes imperative to choose the algorithms as per the available data. In this paper, the efficiency of the given machine learning methods was compared in terms of accuracy and f1-score. Naïve Bayes gave a better overall performance for both accuracy and f1-score and it also remained unaffected with the normalization of data along with LDA, DT and RF. Whereas KNN, SVM and MLP showed a drastic (17% to 86%) improvement in the performance when they are given normalized data as compared to un-normalized data from Alzheimer’s dataset.


Sensors ◽  
2019 ◽  
Vol 19 (6) ◽  
pp. 1461 ◽  
Author(s):  
Juri Taborri ◽  
Eduardo Palermo ◽  
Stefano Rossi

The validity of results in race walking is often questioned due to subjective decisions in the detection of faults. This study aims to compare machine-learning algorithms fed with data gathered from inertial sensors placed on lower-limb segments to define the best-performing classifiers for the automatic detection of illegal steps. Eight race walkers were enrolled and linear accelerations and angular velocities related to pelvis, thighs, shanks, and feet were acquired by seven inertial sensors. The experimental protocol consisted of two repetitions of three laps of 250 m, one performed with regular race walking, one with loss-of-contact faults, and one with knee-bent faults. The performance of 108 classifiers was evaluated in terms of accuracy, recall, precision, F1-score, and goodness index. Generally, linear accelerations revealed themselves as more characteristic with respect to the angular velocities. Among classifiers, those based on the support vector machine (SVM) were the most accurate. In particular, the quadratic SVM fed with shank linear accelerations was the best-performing classifier, with an F1-score and a goodness index equal to 0.89 and 0.11, respectively. The results open the possibility of using a wearable device for automatic detection of faults in race walking competition.


2019 ◽  
Author(s):  
Felix Günther ◽  
Caroline Brandl ◽  
Thomas W. Winkler ◽  
Veronika Wanner ◽  
Klaus Stark ◽  
...  

AbstractImaging technology and machine learning algorithms for disease classification set the stage for high-throughput phenotyping and promising new avenues for genome-wide association studies (GWAS). Despite emerging algorithms, there has been no successful application in GWAS so far. We established machine learning based disease classification in genetic association analysis as a misclassification problem. To evaluate chances and challenges, we performed a GWAS based on automated classification of age-related macular degeneration (AMD) in UK Biobank (images from 135,500 eyes; 68,400 persons). We quantified misclassification of automatically derived AMD in internal validation data (images from 4,001 eyes; 2,013 persons) and developed a maximum likelihood approach (MLA) to account for it when estimating genetic association. We demonstrate that our MLA guards against bias and artefacts in simulation studies. By combining a GWAS on automatically derived AMD classification and our MLA in UK Biobank data, we were able to dissect true association (ARMS2/HTRA1, CFH) from artefacts (near HERC2) and to identify eye color as relevant source of misclassification. On this example of AMD, we are able to provide a proof-of-concept that a GWAS using machine learning derived disease classification yields relevant results and that misclassification needs to be considered in the analysis. These findings generalize to other phenotypes and also emphasize the utility of genetic data for understanding misclassification structure of machine learning algorithms.


2020 ◽  
Vol 39 (5) ◽  
pp. 6579-6590
Author(s):  
Sandy Çağlıyor ◽  
Başar Öztayşi ◽  
Selime Sezgin

The motion picture industry is one of the largest industries worldwide and has significant importance in the global economy. Considering the high stakes and high risks in the industry, forecast models and decision support systems are gaining importance. Several attempts have been made to estimate the theatrical performance of a movie before or at the early stages of its release. Nevertheless, these models are mostly used for predicting domestic performances and the industry still struggles to predict box office performances in overseas markets. In this study, the aim is to design a forecast model using different machine learning algorithms to estimate the theatrical success of US movies in Turkey. From various sources, a dataset of 1559 movies is constructed. Firstly, independent variables are grouped as pre-release, distributor type, and international distribution based on their characteristic. The number of attendances is discretized into three classes. Four popular machine learning algorithms, artificial neural networks, decision tree regression and gradient boosting tree and random forest are employed, and the impact of each group is observed by compared by the performance models. Then the number of target classes is increased into five and eight and results are compared with the previously developed models in the literature.


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