scholarly journals Being physically active minimizes the effects of leg muscle fatigue on obstacle negotiation in people with Parkinson’s disease

2021 ◽  
pp. 110568
Author(s):  
Paulo Cezar Rocha dos Santos ◽  
Fabio Augusto Barbieri ◽  
Diego Orcioli-Silva ◽  
Victor Spiandor Beretta ◽  
Tibor Hortobágyi ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Fatigue ◽  
Physically Active ◽  
Leg Muscle

scholarly journals Daily physical function and frailty in persons with Parkinson's disease: a focus on females

2013 ◽  
Vol 38 (3) ◽  
pp. 358-358
Author(s):  
Kaitlyn P. Roland
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Physical Function ◽  
Muscle Fatigue ◽  
Muscle Activation ◽  
Functional Independence ◽  
Extensive Literature ◽  
Physically Active ◽  
Muscle Activation Patterns ◽  
Physiological Capacity

Persons with Parkinson's disease (PD) are often excluded from frailty studies, and thus little is known about how frailty influences decline in physiological capacity in persons with PD. Impaired physiological capacity impacts the ability to remain physically active, which reduces physical function that is necessary for independent living. The overall purpose of this dissertation was to examine physiological capacity (i.e., muscle activation patterns) and physical activity in males and females with PD during routine daily activities to determine whether they influence physical function and frailty. An extensive literature review of sex differences in PD highlighted that greater declines in gait speed, balance, and motor function occur in females compared with males. This dissertation demonstrated persons with PD, especially females with PD, were weaker and have less muscle quiescence, as measured with gaps in the electromyography, compared with controls and males with PD. These results provide insight into mechanisms (i.e., physiological capacity) that determine PD and sex-related declines in functional performance. In addition, greater muscle activity and less quiescence in females with PD may perpetuate frailty through increased muscle fatigue and slowness of movement. Females with PD are more vulnerable to prefrailty than males and factors that are associated with frailty are quality of life (QoL) and self-reported exhaustion. The neuromuscular changes associated with frailty exacerbate PD, which may create greater muscle fatigue that results in self-reported exhaustion. In conclusion, research presented within this dissertation demonstrates that addressing frailty in PD is important, especially in females who are at greater risk for functional decline. This research presents new knowledge by suggesting that frail females with PD remain physically active during daily life and that disease management may better reflect frailty than disease severity or duration. Understanding how frailty concurrently exists with PD and how these conditions progress within the aging adult may enhance identification and implementation of management strategies aimed at improving functional independence and QoL.

scholarly journals Effects of leg muscle fatigue on gait in patients with Parkinson's disease and controls with high and low levels of daily physical activity

2016 ◽  
Vol 47 ◽  
pp. 86-91 ◽  
Author(s):  
Paulo Cezar Rocha Santos ◽  
Lilian Teresa Bucken Gobbi ◽  
Diego Orcioli-Silva ◽  
Lucas Simieli ◽  
Jaap H. van Dieën ◽  
...  
Keyword(s):  
Physical Activity ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Fatigue ◽  
Daily Physical Activity ◽  
Leg Muscle ◽  
Low Levels

The Relative Contribution of Physical and Cognitive Fall Risk Factors in People With Parkinson’s Disease

2013 ◽  
Vol 28 (3) ◽  
pp. 282-290 ◽  
Author(s):  
Serene S. Paul ◽  
Catherine Sherrington ◽  
Colleen G. Canning ◽  
Victor S. C. Fung ◽  
Jacqueline C. T. Close ◽  
...  
Keyword(s):  
Risk Factors ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Strength ◽  
Fall Prevention ◽  
Fall Risk ◽  
Freezing Of Gait ◽  
Prevention Strategies ◽  
Relative Contribution ◽  
Leg Muscle

Background. In order to develop multifaceted fall prevention strategies for people with Parkinson’s disease (PD), greater understanding of the impact of physical and cognitive performance on falls is required. Objective. We aimed to identify the relative contribution of a comprehensive range of physical and cognitive risk factors to prospectively-measured falls in a large sample of people with PD and develop an explanatory multivariate fall risk model in this group. Methods. Measures of PD signs and symptoms, freezing of gait, balance, mobility, proprioception, leg muscle strength, and cognition were collected on 205 community-dwelling people with PD. Falls were monitored prospectively for 6 months using falls diaries. Results. A total of 120 participants (59%) fell during follow-up. Freezing of gait ( P < .001), dyskinesia ( P = .02), impaired anticipatory and reactive balance ( P < .001), impaired cognition ( P = .002), reduced leg muscle strength ( P = .006), and reduced proprioception ( P = .04) were significantly associated with future falls in univariate analyses. Freezing of gait (risk ratio [RR] = 1.03, 95% confidence interval [CI] = 1.00-1.05, P = .02), impaired anticipatory (RR = 1.01, 95% CI = 1.00-1.02, P = .03) and reactive (RR = 1.26, 95% CI = 1.01-1.58, P = .04) balance, and impaired orientation (RR = 1.28, 95% CI = 1.01-1.62, P = .04) maintained significant associations with falls in multivariate analysis. Conclusion. The study findings elucidate important physical and cognitive determinants of falls in people with PD and may assist in developing efficacious fall prevention strategies for this high-risk group.

scholarly journals Leg muscle strength is reduced in Parkinson's disease and relates to the ability to rise from a chair

2003 ◽  
Vol 18 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Lisa M. Inkster ◽  
Janice J. Eng ◽  
Donna L. MacIntyre ◽  
A. Jon Stoessl
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Strength ◽  
Leg Muscle

scholarly journals Muscle Fatigue Does Not Change the Effects on Lower Limbs Strength Caused by Aging and Parkinson’s Disease

2018 ◽  
Vol 9 (6) ◽  
pp. 988 ◽  
Author(s):  
Vinicius Alota Ignacio Pereira ◽  
Fabio Augusto Barbieri ◽  
Alessandro Moura Zagatto ◽  
Paulo Cezar Rocha dos Santos ◽  
Lucas Simieli ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Fatigue ◽  
Lower Limbs

Effect of Treadmill Walking on Leg Muscle Activation in Parkinson's Disease

2019 ◽  
Vol 22 (1) ◽  
pp. 71-78 ◽  
Author(s):  
Olalla Bello ◽  
Gonzalo Marquez ◽  
Miguel Fernandez-Del-Olmo
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Activation ◽  
Treadmill Walking ◽  
Leg Muscle

scholarly journals Antagonist muscle activity during reactive balance responses is elevated in Parkinson's disease and in balance impairment

2018 ◽  
Author(s):  
Kimberly Carol Lang ◽  
Madeleine Eve Hackney ◽  
Lena H Ting ◽  
Johnathan Lucas McKay
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Muscle Activity ◽  
Muscle Activation ◽  
Research Question ◽  
Support Surface ◽  
Antagonist Activity ◽  
Antagonist Muscle ◽  
Leg Muscle ◽  
Reactive Balance

BACKGROUND: Abnormal antagonist leg muscle activity could indicate increased muscle co-contraction and clarify mechanisms of balance impairments in Parkinson's disease (PD). Prior studies in carefully selected patients showed PD patients demonstrate earlier, longer, and larger antagonist muscle activation during reactive balance responses to perturbations. RESEARCH QUESTION: Here, we tested whether antagonist leg muscle activity was abnormal in a group of PD patients who were not selected for phenotype, and most of whom had volunteered for exercise-based rehabilitation. METHODS: We compared antagonist activation during reactive balance responses to multidirectional support-surface translation perturbations in 31 patients with mild-moderate PD (age 68±9; H&Y 1-3; UPDRS-III 32±10) and 13 matched individuals (age 65±9). We quantified modulation of muscle activity (i.e., the ability to activate and inhibit muscles appropriately according to the perturbation direction) using modulation indices (MI) derived from minimum and maximum EMG activation levels observed across perturbation directions. RESULTS: Antagonist leg muscle activity was abnormal in unselected PD patients compared to controls. Linear mixed models identified significant associations between impaired modulation and PD (P<0.05), PD severity (P<0.01), and balance ability (P<0.05), but not age (P=0.10). SIGNIFICANCE: Antagonist activity is increased during reactive balance responses in PD patients of varying phenotypes who are candidates for rehabilitation. Abnormal antagonist activity may contribute to balance impairments in PD and be a potential rehabilitation target or outcome measure.

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