Evaluation of the interaction of gold nanocages with macrophages in raw 264.7 cell line-HBsAg model in vitro

2017 ◽  
Vol 256 ◽  
pp. S34
Author(s):  
Emine Yavuz ◽  
Emin Umit Bagriacik
Keyword(s):  
Cell Line ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Gold Nanocages ◽  
Raw 264.7 Cell Line

Branched chain amino Acids as in vitro and in vivo Anti-Oxidation Compounds

2021 ◽  
pp. 3899-3904
Author(s):  
Moath Alqaraleh ◽  
Violet Kasabri ◽  
Ibrahim Al-Majali ◽  
Nihad Al-Othman ◽  
Nihad Al-Othman ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Amino Acids ◽  
Branched Chain Amino Acids ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Branched Chain ◽  
Raw 264.7 Cell Line

Background and aims: Branched chain amino acids (BCAAs) can be tightly connected to metabolism syndrome (MetS) which can be counted as a metabolic indicator in the case of insulin resistance (IR). The aim of this study was to assess the potential role of these acids under oxidative stress. Material and Methods: the in vitro antioxidant activity of BCAAs was assessed using free radical 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) scavenging assays. For further check, a qRT-PCR technique was madefor detection the extent of alterations in gene expression of antioxidative enzymes (catalase and glutathione peroxidase (Gpx)) in lipopolysaccharides (LPS(-induced macrophages RAW 264.7 cell line. Additionally, BCAAs antioxidant activity was evaluated based on plasma H2O2 levels and xanthine oxidase (XO) activity in prooxidative LPS-treated mice. Results: Different concentrations of BCAAs affected on DPPH radical scavenging activity but to lesser extent than the ascorbic acid. Besides, BCAAs obviously upregulated the gene expression levels of catalases and Gpx in LPS-modulated macrophage RAW 264.7 cell line. In vivo BCAAs significantly minimized the level of plasma H2O2 as well as the activity of XO activity under oxidative stress. Conclusion: our current findings suggest that BCAAs supplementation may potentially serve as a therapeutic target for treatment of oxidative stress occurs with atherosclerosis, IR-diabetes, MetS and tumorigenesis.

scholarly journals Exposure to particle debris generated from passenger and truck tires induces different genotoxicity and inflammatory responses in the RAW 264.7 cell line

PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0222044 ◽  
Author(s):  
Anna Poma ◽  
Giulia Vecchiotti ◽  
Sabrina Colafarina ◽  
Osvaldo Zarivi ◽  
Lorenzo Arrizza ◽  
...  
Keyword(s):  
Cell Line ◽  
Inflammatory Responses ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Truck Tires ◽  
Raw 264.7 Cell Line

Winter urban air particles from Rome (Italy): Effects on the monocytic–macrophagic RAW 264.7 cell line

2005 ◽  
Vol 99 (3) ◽  
pp. 344-354 ◽  
Author(s):  
Roberta Pozzi ◽  
Barbara De Berardis ◽  
Luigi Paoletti ◽  
Cecilia Guastadisegni
Keyword(s):  
Cell Line ◽  
Urban Air ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Raw 264.7 Cell Line

Exposure to radiation from single or combined radio frequencies provokes macrophage dysfunction in the RAW 264.7 cell line

2018 ◽  
Vol 94 (6) ◽  
pp. 607-618 ◽  
Author(s):  
Alberto López-Furelos ◽  
Aarón A. Salas-Sánchez ◽  
Francisco J. Ares-Pena ◽  
José M. Leiro-Vidal ◽  
Elena López-Martín
Keyword(s):  
Cell Line ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Macrophage Dysfunction ◽  
Radio Frequencies ◽  
Raw 264.7 Cell Line

scholarly journals A New Bithiophene from the Root of Echinops grijsii

2015 ◽  
Vol 10 (12) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Fang-Pin Chang ◽  
Chien-Chih Chen ◽  
Hui-Chi Huang ◽  
Sheng-Yang Wang ◽  
Jih-Jung Chen ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Cell Line ◽  
Natural Source ◽  
Inflammatory Activity ◽  
Raw 264.7 ◽  
Raw 264.7 Cell ◽  
Anti Inflammatory ◽  
First Time ◽  
Raw 264.7 Cell Line

A new bithiophene, 5-(4-hydroxy-3-methoxy-1-butyny)-2,2′-bithiophene (1), and sixteen known thiophenes: 2-(3,4-dihydroxybut-1-ynyl)-5-(penta-1,3-diynyl)thiophene (2), α-terthienyl (3), 5-(3,4-dihydroxybut-1-ynyl)-2,2′-bithiophene (4), 5-acetyl-2,2′-bithiophene (5), 5-formyl-2,2′-bithiophene (6), methyl 2,2′-bithiophene-5-carboxylate (7), 5-(but-3-en-1-ynyl)-2,2′-bithiophene (8), 5-(4-isovaleroyloxybut-1-ynyl)-2,2′-bithiophene (9), cardopatine (10), isocardopatine (11), 5-(3-hydroxy-4-isovaleroyloxybut-1-ynyl)-2,2′-bithiophene (12), 5-(3-hydroxymethyl-3-isovaleroyloxyprop-1-ynyl)-2,2′-bithiophene (13), 5-(4-hydroxy-1-butynyl)-2,2′-bithiophene (14), 5-(4-acetoxy-1-butynl)-2,2′-bithiophene (15), 2,2′-bithiophene-5-carboxylic acid (16) and 2-(4-hydroxybut-1-ynyl)-5-(penta-1,3-diynyl)thiophene (17) were isolated from the roots of Echinops grijisii Hance. Among them, compounds 6, 7 and 16 were isolated from a natural source for the first time. Compounds 2, 4 and 14 exhibited significant anti-inflammatory activity against nitrite of LPS-stimulated production in the RAW 264.7 cell line.

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